A5019387928- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Prenatal Screening and Diagnostics
- Preterm Birth and Chorioamnionitis
- Neonatal Respiratory Health Research
- Simulation-Based Education in Healthcare
- Maternal and fetal healthcare
- Health Education and Validation
- Pregnancy-related medical research
- Tracheal and airway disorders
- COVID-19 Impact on Reproduction
- Congenital Heart Disease Studies
- Nursing Diagnosis and Documentation
- Pregnancy and Medication Impact
- Bone and Joint Diseases
- Nutrition and Health in Aging
- Ethics in medical practice
- Cardiovascular Issues in Pregnancy
- Disaster Response and Management
- Fibroblast Growth Factor Research
- Neonatal and fetal brain pathology
- Bone health and treatments
- Reproductive System and Pregnancy
- Frailty in Older Adults
Imperial College Healthcare NHS Trust
2021-2024
St Mary's Hospital
2023-2024
St. Mary's Hospital
2023-2024
King's College Hospital
2016-2024
Singapore General Hospital
2023-2024
Harris Birthright Research Centre for Fetal Medicine
2015-2022
St Mary's Hospital
2021
University of Exeter
2019
King's College London
2018
University Hospital Lewisham
2018
To examine the performance of screening for early, preterm and term pre-eclampsia (PE) at 11-13 weeks' gestation by maternal factors combinations mean arterial pressure (MAP), uterine artery (UtA) pulsatility index (PI), serum placental growth factor (PlGF) pregnancy-associated plasma protein-A (PAPP-A).The data this study were derived from three previously reported prospective non-intervention studies 11 + 0 to 13 6 in a combined total 61 174 singleton pregnancies, including 1770 (2.9%)...
ABSTRACT Objective To test the hypothesis that performance of first‐trimester screening for pre‐eclampsia (PE) by a method uses Bayes' theorem to combine maternal factors with biomarkers is superior defined current National Institute Health and Care Excellence (NICE) guidelines. Methods This was prospective multicenter study (screening program (SPREE)) in seven Service maternity hospitals England, women recruited between April December 2016. Singleton pregnancies at 11–13 weeks' gestation...
To establish a normal range of birth weights for gestational age at delivery and to compare the proportion live births stillbirths that are classified as small-for-gestational (SGA) according our vs INTERGROWTH-21st standard.The study population comprised 113 019 437 (0.4%) stillbirths. The inclusion criterion establishing was phenotypically neonate ≥ 24 weeks' gestation exclusion criteria were smoking prepregnancy hypertension, diabetes mellitus, systemic lupus erythematosus or...
ABSTRACT Objectives To examine the effect of first‐trimester screening for pre‐eclampsia (PE) on prediction delivering a small‐for‐gestational‐age (SGA) neonate and prophylactic use aspirin prevention SGA. Methods The data this study were derived from two multicenter studies. In SPREE, we investigated performance PE by combination maternal characteristics biomarkers at 11–13 weeks' gestation. ASPRE, women with singleton pregnancy identified combined as being high risk preterm (> 1 in 100)...
ABSTRACT Objective To report the incidence of preterm pre‐eclampsia (PE) in women who are screen positive according to criteria National Institute for Health and Care Excellence (NICE) American College Obstetricians Gynecologists (ACOG), compare with that those or negative by The Fetal Medicine Foundation (FMF) algorithm. Methods This was a secondary analysis data from ASPRE study. study population consisted singleton pregnancy underwent prospective screening PE means FMF algorithm, which...
Abstract Objective To compare the predictive performance for preterm‐pre‐eclampsia (PE) in first‐trimester screening by serum placental growth factor (PlGF) versus pregnancy associated plasma protein‐A (PAPP‐A), combination with maternal risk factors, mean arterial pressure (MAP) and uterine artery pulsatility index (UtA‐PI), after adjustment effect of aspirin women receiving this treatment. Design Non‐intervention multicentre studies PE singleton pregnancies. Setting Maternity hospitals....
To estimate the patient-specific risk of pre-eclampsia (PE) at 31-34 weeks' gestation by a combination maternal characteristics and medical history with multiples median (MoM) values serum placental growth factor (PlGF) soluble fms-like tyrosine kinase-1 (sFlt-1) to compare performance screening that achieved sFlt-1/PlGF ratio.This was prospective observational study in women attending third-trimester ultrasound scan weeks as part routine pregnancy care. We estimated for PE delivery within 4...
Abstract Background Euglycaemic ketoacidosis (EKA) is an infrequent but serious condition which usually follows a period of starvation, severe vomiting or illness in individuals with without diabetes. Ketoacidosis associated materno-fetal morbidity and mortality necessitating prompt diagnosis management. Physiological increases insulin resistance render pregnancy diabetogenic state increased susceptibility to ketosis. COVID-19 worse clinical outcomes patients diabetes independent risk factor...
Abstract Background Artificial intelligence (AI) has shown potential in improving the performance of screening fetal anomaly ultrasound scans. We aimed to assess effect AI on scanning, terms diagnostic performance, biometry, scan duration, and sonographer cognitive load. Methods This was a randomised, single centre, open label trial large teaching hospital. Pregnant participants with congenital heart disease (CHD) healthy fetuses were recruited scanned both methods. Screening sonographers...
Pre-eclampsia (PE), which affects about 2% of pregnancies, is a major cause maternal and perinatal morbidity mortality. Early detection PE can improve pregnancy outcome by providing timely intervention closer monitoring. The current guideline from the UK National Institute for Health Care Excellence (NICE) recommends that, at booking visit, women identified with one risk factor or more than moderate should be advised to take low-dose aspirin daily 12 weeks until delivery. However,...
Abstract Objective To report the predictive performance for preterm birth (PTB) of Fetal Medicine Foundation (FMF) triple test and National Institute health Care Excellence (NICE) guidelines used to screen pre‐eclampsia examine impact aspirin in prevention PTB. Design Secondary analysis data from SPREE study ASPRE trial. Setting Multicentre studies. Population In SPREE, women with singleton pregnancies had screening at 11–13 weeks gestation by FMF method NICE guidelines. There were 16 451...
( Am J Obstet Gynecol . 2018;218:612.e1–e6) Preeclampsia is a major cause of maternal and perinatal death other adverse outcomes for mothers babies, has important health care cost implications. Previous studies have found reduction the risk preeclampsia with use aspirin. This study aimed to examine effect aspirin on length stay in neonatal intensive unit (NICU), as well evaluate impact screening treatment high-risk patients costs.
To explore the experience of second victim symptoms and adverse outcomes among nurses working in public healthcare institutions; understand preferred components a structured support programme; barriers to accessing existing strategies.
(Abstracted from BJOG 2024;131:483–492) Preeclampsia is a serious complication of pregnancy, and efforts have been made to increase the ability predict when an individual will develop condition. Guidelines National Institute for Health Care Excellence (NICE) are based on risk factor scoring, with high-risk women having either 1 major or 2 moderate factors.
Objective: To compare pre-eclampsia (PE) risk strategies among Black vs. White ethnicity women. Design: Prospective non-intervention cohort studies. Setting: Maternity hospitals, United Kingdom and Europe. Population: Singleton pregnancies delivering at ≥24 weeks, without major anomalies. Methods: PE was determined by National Institute for Health Care Excellence (NICE) guidance, NICE guidance modified adding as a moderate-risk factor, the Fetal Medicine Foundation (FMF) competing-risks...
(Abstracted from Ultrasound Obstet Gynecol 2018;51:738–742) The current approach to screening for preeclampsia (PE) is identify risk factors maternal demographic characteristics and medical history (maternal factors). According the National Institute Health Care Excellence (NICE), in United Kingdom, women are considered be at high of developing PE if they have any one high-risk factor (hypertensive disease previous pregnancy, chronic hypertension, renal disease, diabetes mellitus, or...
Background: Blood transfusion is a life-saving treatment that requires comprehensive knowledge and compliance to safety, administration, management of blood process. It core competency for registered nurse. Competency assessments are annually conducted as regulatory requirement quality assurance within our institution. Prior using serious games, assessment involved an online learning module followed by face-to-face assessment. This had limitations such limited opportunities, potential lack...
To describe the use of laser, endoscopic balloon dilatation with jet ventilation anaesthesia in treatment pregnant women idiopathic subglottic stenosis.This is a case review stenosis, presenting to tertiary referral centre worsening breathlessness. Data were extracted from patient notes.Four underwent surgical management stenosis pregnancy. One required two procedures during course their pregnancy due restenosis. All had improvement symptoms post-operatively and went on deliver healthy...
Background: Geriatric syndromes affect the quality of life older adults and pose a heavy burden on society families. Comprehensive geriatric assessment (CGA) is multi-dimensional diagnotic process including medical assessment, physical function cognitive psychological social/environmental factors assessment. Objective: This study investigated ten common by CGA in hospitalized patients aimed to provide guidance for comprehensive management senile patients. Methods: A cross-sectional was...
Nasogastric tubes are widely used in clinical practice for enteral nutrition, medication administration, and gastric decompression. Common complications of their use-such as tube blockage, displacement, accidental removal-are well described the literature. However, knotting-a complication that occurs when a knot forms nasogastric situ-is rare. This report presents case became knotted, causing difficulty its removal. Key takeaways from this discussed, among them more emphasis should be placed...