- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Policy and Management
- Delphi Technique in Research
- Health Policy Implementation Science
- Economic and Environmental Valuation
- Global Health Care Issues
- Health disparities and outcomes
- Childhood Cancer Survivors' Quality of Life
- Pharmaceutical Economics and Policy
- Economic and Financial Impacts of Cancer
- Adolescent and Pediatric Healthcare
- Cancer survivorship and care
- Urinary Bladder and Prostate Research
- Workplace Health and Well-being
- Meta-analysis and systematic reviews
- Pelvic floor disorders treatments
- Pharmaceutical studies and practices
- Liver Disease and Transplantation
- Vaccine Coverage and Hesitancy
- Asthma and respiratory diseases
- Health and Wellbeing Research
- School Health and Nursing Education
- Clinical practice guidelines implementation
- Control Systems in Engineering
- Algal biology and biofuel production
Office Of Health Economics
2016-2025
National University of Singapore
2020-2025
National University Health System
2020-2025
KK Women's and Children's Hospital
2024
Eticas Research & Consulting (Spain)
2013-2016
Gavekal Intelligence Software (France)
2012-2013
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2007-2010
Municipal Institute for Medical Research
2008-2009
University Hospitals Coventry and Warwickshire NHS Trust
2006
GlaxoSmithKline (Canada)
2006
This article introduces the new 5-level EQ-5D (EQ-5D-5L) health status measure.EQ-5D currently measures using three levels of severity in five dimensions. A EuroQol Group task force was established to find ways improving instrument's sensitivity and reducing ceiling effects by increasing number levels. The study performed United Kingdom Spain. Severity labels for 5 each dimension were identified response scaling. Focus groups used investigate face content validity versions, including...
To develop a self-report version of the EQ-5D for younger respondents, named EQ-5D-Y (Youth); to test its comprehensibility children and adolescents compare results obtained using standard adult EQ-5D-Y.An international task force revised content wording ensure relevance clarity young respondents. Children's adolescents' understanding was tested in cognitive interviews after instrument translated into German, Italian, Spanish Swedish. Differences between regarding frequencies reported...
To examine the feasibility, reliability, and validity of newly developed EQ-5D-Y.The EQ-5D-Y was administered in population samples children adolescents Germany, Italy, South Africa, Spain, Sweden. Percentages missing values reported problems were calculated. Test-retest reliability determined. Spearman's rank correlation coefficients with other generic measures HRQOL Known groups' examined by comparing groups a priori expected differences HRQOL.Between 91 100% respondents provided valid...
Few studies have compared preference values for health states obtained in different countries. The present study Spanish and United Kingdom (UK) time trade-off EuroQol-5D states. same elicitation protocol was followed both Differences 43 rated directly were analyzed using t tests, regression coefficients generated by random effects modeling aggregating the 2 value sets dummy variables to analyze country effect dimension level of severity. For milder states, UK assignation similar;...
There is a lack of consensus as to the best way monitoring psoriasis severity in clinical trials. The Psoriasis Area and Severity Index (PASI) most frequently used system Physician's Global Assessment (PGA) also often used. However, both instruments have some drawbacks neither has been fully evaluated terms 'validity' 'reliability' rating scale. Lattice System (LS-PGA) scale recently developed address disadvantages PASI PGA.To evaluate inter-rater intrarater reliability PASI, PGA LS-PGA.On...
To develop a Chinese version of the new, 5-level EQ-5D descriptive system (EQ-5D-5L) from existing EQ-5D-3L by identifying label wording suitable for constructing EQ-5D-5L's 5-point response scales.In face-to-face interviews, perceived severity selected labels when they were used to describe health problems was measured 50 native speakers using 0 (no problems) 100 (the worst visual analog scale. Selection based on scores and semantic similarity with in English Spanish EQ-5D-5L.The supported...
EQ-5D-Y is a generic measure of health status for children and adolescents aged 8-15 years. Originally, it has three levels severity in each dimension (3L). This study aimed to develop descriptive system with an increased number test comprehensibility feasibility.
For nearly a decade, value sets for the EQ-5D-Y were not available, reflecting challenges in valuing child HRQoL. A methodological research programme led to publication of valuation protocol 2020, which was rapidly taken up by local study teams. By end 2022, between 11 and 17 will be more than any other HRQoL measure. It is timely review experience those using identify early learnings remaining issues where needed.
The three-level and five-level child-friendly versions (EQ-5D-Y) are widely employed for assessing health-related quality of life (HRQoL) in children. However, their effectiveness asthma remains understudied. We aimed to assess psychometric properties asthmatic Seventy-six dyads patients parents completed EQ-5D-Y-5L EQ-5D-Y-3L, respectively, at two visits. Test-retest reliability patient-caregiver agreement were assessed using intraclass correlation coefficient (ICC). Known-groups validity...
Abstract Background In 2019, the EuroQol Group developed a ‘beta’ 5-level version of EQ-5D-Y (Y-5L) by increasing number descriptive levels to five for each health dimension, as compared standard 3-level (Y-3L). Objective To assess patient-caregiver agreement and test–retest reliability Y-5L Y-3L in paediatric patients with haematological malignancies. Methods Paediatric inpatients aged 8–17 years were interviewed questionnaires twice, while their caregivers at same time using proxy versions...
Background. "Feeling thermometers" and category rating scales (CRS) can be used to measure self-rated health, though the interpretation of scores on feeling thermometer may problematic. Objectives. To analyze correspondence between health EuroQol-5D "feeling thermometer" a five-Point CRS. determine influence sociodemographic variables correspondence. Research Design. Correspondence EQ-5D "thermometer" CRS categories was determined in within-subjects design using data from large-scale survey....
Background: We compared the psychometric properties of ESPRINT‐15, short form a new Spanish instrument to measure health‐related quality life in allergic rhinitis (AR) patients, with those Mini‐Rhinoconjunctivitis Quality Life Questionnaire (MiniRQLQ). Methods: The questionnaires were patients intermittent (IAR) or persistent AR prospective, observational study. Floor and ceiling effects, internal consistency (Cronbach’s alpha), test–retest reliability (intraclass correlation coefficient;...