A5010849191- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Contact Dermatitis and Allergies
- Food Allergy and Anaphylaxis Research
- Olfactory and Sensory Function Studies
- Respiratory and Cough-Related Research
- Sinusitis and nasal conditions
- Drug-Induced Adverse Reactions
- Lichen and fungal ecology
- Nasal Surgery and Airway Studies
- Urticaria and Related Conditions
- Dermatology and Skin Diseases
- Synthesis and properties of polymers
- Ocular Surface and Contact Lens
- Antiplatelet Therapy and Cardiovascular Diseases
- Mast cells and histamine
- Advanced Chemical Sensor Technologies
- Pediatric health and respiratory diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Pharmaceutical studies and practices
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Occupational exposure and asthma
- Insect and Pesticide Research
- Respiratory viral infections research
- Respiratory Support and Mechanisms
Hôpital Beaujon
2025
Hospital Clínico Universitario Lozano Blesa
2013-2024
Instituto de Investigación Sanitaria Aragón
2012-2024
Universidad de Zaragoza
2021-2024
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2019-2021
Instituto de Salud Carlos III
2019-2021
Universitat de Barcelona
2021
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2021
Servicio Aragonés de Salud
2009
Triangle
1996
Summary Background Allergy diagnosis needs to be improved in patients suffering from pollen polysensitization due the existence of possible confounding factors this type patients. Objective To evaluate new diagnostic strategies by comparing skin responses pan‐allergens and conventional allergenic extracts with specific IgE (sIgE) purified allergen molecules. Methods One thousand three hundred twenty‐nine pollen‐allergic were diagnosed a combination an vitro method panel 13 allergens,...
Background Allergic rhinitis (AR) is a highly prevalent allergic disease and also counts among the 10 most frequent reasons for medical consultation. Its impact on quality of life (QoL) work productivity has been established but comparisons with other diseases are rare in literature. The aim this study was to evaluate AR health-related QoL (HRQoL) primary care patients, compared such as hypertension, diabetes mellitus (DM) type II, symptomatic depression. Methods Six hundred sixteen patients...
Despite the socioeconomic importance of allergic rhinitis (AR), very few prospective studies have been performed under conditions clinical practice and with a sufficiently long observation period outside trial scenario. We prospectively estimated direct indirect costs AR in patients attending specialized clinics Spain.Patients were recruited at random from allergy outpatient 101 health centers throughout Spain over 12 months. multicenter, observational, study practice. analyzed funder...
Sleep is impaired in allergic rhinitis (AR) patients, with subsequent effects on daytime performance and health-related quality of life (QOL). AR has rarely been considered through validated tools consensus classifications.To evaluate sleep somnolence to estimate its relationship disease severity according Allergic Rhinitis Its Impact Asthma (ARIA) conventional modified classifications, as well terms QOL comorbidities.Allergic adult patients were evaluated a prospective, observational,...
Abstract Background In corticosteroid-resistant acute severe ulcerative colitis (ASUC), second-line treatment involves infliximab or cyclosporine (CYCLO). With increasing antiTNFα exposed patients, CYCLO is often chosen to prevent emergency colectomy but limited the induction phase due tolerability, serving as a bridge until effective maintenance therapy. this setting, data on vedolizumab (VDZ) and ustekinumab (UST) make choice of an optimal strategy challenging. This study aimed compare...
Background: We compared the psychometric properties of ESPRINT‐15, short form a new Spanish instrument to measure health‐related quality life in allergic rhinitis (AR) patients, with those Mini‐Rhinoconjunctivitis Quality Life Questionnaire (MiniRQLQ). Methods: The questionnaires were patients intermittent (IAR) or persistent AR prospective, observational study. Floor and ceiling effects, internal consistency (Cronbach’s alpha), test–retest reliability (intraclass correlation coefficient;...
Summary Background Chenopodiaceae pollen is considered the main cause of allergy in desert countries and its incidence world‐wide increasing by desertization extensive zones. Although correlation between sensitization to Chenopodium album Salsola kali pollens patients suffering from high, a significant number exhibited IgE sensitivity exclusively towards S. . Objective To analyse this differential reactivity purify, clone characterize putative responsible allergen. Methods Immunoblotting was...
Allergic rhinitis (AR) is a common disease with major socioeconomic burden and significant impact on quality of life. The aim this study was to discriminate between moderate severe AR patients whether receiving treatment or not, using modified criterion allergic its asthma (ARIA) classification.The ARIA severity classification (J Allergy Clin Immunol, 120, 2007, 359) categorizes as mild (no items affected), (1-3 (all four affected). We applied these criteria 1666 treated 1058 untreated...
<i>Background:</i> The objective of this study was to evaluate the effects omalizumab on bronchoconstriction induced by methacholine and adenosine 5′-monophosphate (AMP). <i>Methods:</i> Thirty-four subjects with mild moderate allergic asthma were randomized receive placebo (n = 16) or 18) subcutaneously during 12 weeks. Airway responsiveness AMP measured at baseline after 4 weeks treatment, whereas response treatment. <i>Results:</i> After increase in...
Background Nasal polyposis (NP) is a chronic inflammatory disease of unknown etiology that impairs quality life (QoL). The role atopy in NP not established. aim this study was to describe the clinical characteristics and QoL broad sample patients with evaluate influence allergy on disease. Methods A multicenter, observational, cross-sectional conducted 67 units Spain. nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity were diagnosed following EP 3 OS guidelines. Rhinitis asthma...
Introduction: Allergic rhinitis (AR) is a common disease with major socieconomic burden and significant impact on quality of life. Objective: The objective the study was to assess AR severity, using modified ARIA (m-ARIA) severity criterion in order discriminate among moderate severe AR, symptoms life assessed questionnaire ESPRINT-15. Methods: specific (ESPRINT-15) applied over thousand untreated RA patients. Severity evaluated by m-ARIA classification, which categorizes as mild, moderate,...