A5103192130- COVID-19 and healthcare impacts
- Cystic Fibrosis Research Advances
- COVID-19 Clinical Research Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory viral infections research
- Asthma and respiratory diseases
- Climate Change and Health Impacts
- Urticaria and Related Conditions
- Tracheal and airway disorders
- Drug-Induced Adverse Reactions
- Neonatal Respiratory Health Research
- Contact Dermatitis and Allergies
- Plant Virus Research Studies
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- Nematode management and characterization studies
- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Plant and Fungal Interactions Research
- Viral Infections and Immunology Research
- Olfactory and Sensory Function Studies
- Autoimmune Bullous Skin Diseases
- Healthcare cost, quality, practices
- Viral gastroenteritis research and epidemiology
- Pneumonia and Respiratory Infections
HM Hospitales
2023-2025
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2022-2025
Instituto de Salud Carlos III
2022-2025
Spanish National Centre for Cardiovascular Research
2025
Camilo José Cela University
2023-2025
Universidad Politécnica de Madrid
2020-2024
Centre for Plant Biotechnology and Genomics
2020-2024
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria
2020-2024
Universidad Autónoma de Madrid
2022-2023
Hospital Universitario de La Princesa
2022-2023
Sleep is impaired in allergic rhinitis (AR) patients, with subsequent effects on daytime performance and health-related quality of life (QOL). AR has rarely been considered through validated tools consensus classifications.To evaluate sleep somnolence to estimate its relationship disease severity according Allergic Rhinitis Its Impact Asthma (ARIA) conventional modified classifications, as well terms QOL comorbidities.Allergic adult patients were evaluated a prospective, observational,...
ABSTRACT Background Commissural misalignment (CMA) has demonstrated to difficult future coronary access in self‐expandable prosthesis and been related with subclinical leaflet thrombosis a potential increase valve gradients aortic regurgitation at follow‐up. Aims The aim of our study was assess the commissural alignment balloon expandable SAPIEN 3 (Edwards Lifesciences) evaluate its impact on transvalvular gradient mortality 5 years Methods Consecutive patients treated guided intraprocedural...
Background/Objectives: Respiratory syncytial virus (RSV) represents a significant cause of acute respiratory infections (ARIs) in adults aged 60 years and older, often leading to severe clinical outcomes high healthcare costs. This study aimed evaluate the economic burden RSV compared other ARIs, focusing on specific age groups, comorbidities, demographic factors. Methods: A retrospective observational was conducted using electronic medical records ≥60 hospitalized for including RSV, Spain....
<title>Abstract</title> <bold>Purpose: </bold>Cystic fibrosis (CF) is a genetic disease caused by mutations in the CFTR gene, leading to multisystemic complications, particularly lungs. dysfunction results altered ion transport, chronic inflammation, and progressive lung damage. The triple therapy elexacaftor/tezacaftor/ivacaftor (ETI) has demonstrated significant improvements pulmonary function quality of life. This study aimed evaluate anti-inflammatory effects ETI analysing systemic...
Introducción. Describir el patrón epidemiológico de la pandemia COVID-19 durante todo Estado Alarma en España. Métodos. Estudio retrospectivo, observacional, cohorte y multicéntrico. Criterios inclusión: edad ≥18 años, ingreso por neumonía cualquiera los centros del Grupo Hospitales HM. exclusión: alta voluntaria, fallecimiento servicio urgencias, traslado a fuera grupo HM o datos incompletos. Alarma: 31/01/2020 al 05/07/2023. Se definió como variante predominante aquella que superó 50%...
Abstract Background This study aimed to assess how Elexacaftor/Tezacaftor/Ivacaftor (ETI) influences lung function, Body Mass Index (BMI), Sweat Test (ST) and mental health of Cystic Fibrosis (CF) patients, emphasizing on depression anxiety. Methods We conducted an observational, prospective, multicentre including 108 patients over 18 years old who initiated ETI therapy between December 2019 2023. Patients underwent regular evaluations, clinical, functional, microbiological assessments,...
Seventeen patients with aspirin-induced asthma were studied, the majority being intolerant to more than one analgesic. In addition asthma, eleven had sinusitis and eight nasal polyps. Serum IgE levels normal a mean of 295 iu/ml. However, some positive cutaneous PK tests against inhalants non-analgesic drugs. Spirometry showed bronchial obstruction be mild. all hyper-reactive acetylcholine. Oral provocation aspirin alone also prior administration sodium cromoglycate (SCG) by inhalation...
We previously reported an increase in respiratory mortality 2020 Spain after COVID-19. It is unclear if this rise sustained the longer-term. aimed to determine whether 2021 returned pre-pandemic levels.In observational, large study using official National Institute of Statistics data, we explored deaths due diseases, that is, all causes death by standard WHO list diseases system plus COVID-19, tuberculosis and lung cancer. Using latest available data Spain, analyzed changes pattern from...
Background/Objectives: Respiratory syncytial virus (RSV) is a major cause of hospitalization in infants. Nirsevimab has demonstrated to be promising tool for preventing severe RSV disease. Although clinical trials have the efficacy disease, evidence regarding its performance real-world settings still limited due recent introduction. This study aims fill this knowledge gap by evaluating impact cohort infants and determining effectiveness reducing burden Methods: A retrospective...
Abstract The emergence of viral diseases results from novel transmission dynamics between wild and crop plant communities. bias studies towards pathogenic viruses crops has distracted knowledge non-antagonistic symbioses in plants. Here, we implemented a high-throughput approach to compare the viromes melon (Cucumis melo) plants (Crop) adjacent boundaries (Edge). Each 41-plant species examined was infected by at least one virus. interactions 104 virus operational taxonomic units (OTUs) with...
The evolution and diversification of ssRNA plant viruses are often examined under reductionist conditions that ignore potentially much wider biotic interactions. host range a virus is central to interactions at higher levels organized by both fitness ecological criteria. Here we employ strategy minimize sampling biases across distinct communities combine it with high-throughput sequencing approach examine the influence four habitats on Watermelon mosaic (WMV). Local, regional global genetic...
Infection by SARS-CoV-2 has unquestionably had an impact on the health of patients with chronic respiratory airway diseases, such as COPD and asthma, but little information is available about its bronchiectasis. The objective present study was to analyze effect pandemic state health, characteristics, clinical severity (including number exacerbations) non-cystic fibrosis bronchiectasis.This multicenter, observational, ambispective (with data collected before during pandemic), included 150...
Introduction: Malnutrition has always been a problem in CF (cystic fibrosis) patients; however, new treatments with CFTR fibrosis transmembrane conductance regulator protein) modulators have led to weight gain, some patients at risk of overweight and obesity. Objective: Our study aimed analyze the evolution BMI (body mass index) after one year treatment triple therapy factors associated gain undergoing protein (ETI) (elexacaftor/tezacaftor/ivacaftor). Methods: We conducted prospective,...
Background An association of ABO blood group and COVID-19 remains controversial. Methods Following STROBE guidance for observational research, we explored the distribution in patients hospitalized acute those with Long COVID. Contingency tables were made risk factors using crude adjusted Mantle-Haentzel odds ratios (OR 95% CI). Results Up to September 2022, there a total 5,832 hospitalizations our hospital, corresponding 5,503 individual patients, whom determination was available 1,513...
Serum samples from eighty-one patients with suspected penicillin allergy were investigated Phadebas RAST using the derivatives Benzylpenicilloyl-human serum albumin (PBO-HSA) and Phenoxymethylpenicilloyl-human (PMPO-HSA) results compared skin test clinical data. Of sixty-one who had anaphylactic shock and/or urticaria as a possible consequence of administration, reagins against PBO-HAS PMPO-HSA could be detected in thirty-four cases (56%). Five per cent these patients, positive results,...