Elena García Castillo
A5028112682- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Asthma and respiratory diseases
- Cystic Fibrosis Research Advances
- COVID-19 Clinical Research Studies
- Tracheal and airway disorders
- Air Quality and Health Impacts
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- SARS-CoV-2 and COVID-19 Research
- Respiratory and Cough-Related Research
- Inhalation and Respiratory Drug Delivery
- Long-Term Effects of COVID-19
- Smoking Behavior and Cessation
- Obstructive Sleep Apnea Research
- Renal function and acid-base balance
- Pleural and Pulmonary Diseases
- Chronic Disease Management Strategies
- Infectious Disease Case Reports and Treatments
- Actinomycetales infections and treatment
- Patient-Provider Communication in Healthcare
- Pulmonary Hypertension Research and Treatments
- Eosinophilic Esophagitis
- Neuroscience of respiration and sleep
- SARS-CoV-2 detection and testing
- Dysphagia Assessment and Management
Hospital Universitario de La Princesa
2015-2024
Universidad Autónoma de Madrid
2018-2023
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2022-2023
Instituto de Salud Carlos III
2022-2023
Intensive Care Society
2020
Early kinetics of SARS-CoV-2 viral load (VL) in plasma determined by quantitative reverse-transcription polymerase chain reaction (RT-PCR) was evaluated as a predictor poor clinical outcome prospective study and assessed retrospective validation cohort. Prospective observational single-center including consecutive adult patients hospitalized with COVID-19 between November 2020 January 2021. Serial samples were obtained until discharge. Quantitative RT-PCR performed to assess VL. The main...
Smoke-free policies are effective in preventing secondhand smoke (SHS) exposure, but their adoption at home remains largely voluntary. This study aimed to quantify SHS exposure homes with residents who Europe according households' characteristics, tobacco consumption habits, and national contextual factors. Cross-sectional (March 2017–September 2018) based on measurements of air nicotine inside 162 from nine European countries. We installed passive samplers for seven consecutive days monitor...
Abstract Some patients with COVID-19 pneumonia develop an associated cytokine storm syndrome that aggravates the pulmonary disease. These may benefit of anti-inflammatory treatment. The role colchicine in hospitalized and established hyperinflammation remains unexplored. In a prospective, randomized controlled, observer-blinded endpoint, investigator-initiated trial, 240 were randomly allocated to receive oral or not. primary efficacy outcome measure was composite non-invasive mechanical...
Background An association of ABO blood group and COVID-19 remains controversial. Methods Following STROBE guidance for observational research, we explored the distribution in patients hospitalized acute those with Long COVID. Contingency tables were made risk factors using crude adjusted Mantle-Haentzel odds ratios (OR 95% CI). Results Up to September 2022, there a total 5,832 hospitalizations our hospital, corresponding 5,503 individual patients, whom determination was available 1,513...
This study aimed to estimate airborne nicotine concentrations and nicotine, cotinine, tobacco-specific nitrosamines (TSNAs) in settled dust from private cars Spain the UK.
In 2019, The Global Initiative for Chronic Obstructive Lung Disease (GOLD) modified the grading system patients with COPD, creating 16 subgroups (1A–4D). As part of COPD Cohorts Collaborative International Assessment (3CIA) initiative, we aim to compare mortality prediction 2015 and 2019 GOLD staging systems. We studied 17 139 from 3CIA study, selecting those complete data. Patients were classified by ABCD systems, compared predictive ability 5-year both classifications. total, enrolled in...
Background: Interleukin 6 (IL6) levels and SARS-CoV-2 viremia have been correlated with COVID-19 severity. The association over time between them has not assessed in a prospective cohort. Our aim was to evaluate the relationship evolution of IL6 Methods: Secondary analysis from cohort including hospitalized patients Hospital Universitario La Princesa November 2020 January 2021. Serial plasma samples were collected admission until discharge. Viral load quantified by Real-Time Polymerase Chain...
<h3>BACKGROUND:</h3> Nocturnal desaturation in cystic fibrosis (CF) may have prognostic implications because a significant and maintained nocturnal can contribute to the development progression of pulmonary hypertension with cor pulmonale. Its relation exercise has not been sufficiently studied. We aimed determine whether during 6MWT be an indicator adult subjects CF. <h3>METHODS:</h3> 57 were included: 50.9% male, 27.5 ± 7.7 y old, mean FEV<sub>1</sub> = 2.37 0.74 L, %FEV<sub>1</sub> 67...
The patient experience is defined as all the interactions that occur between patients and healthcare system. of with respiratory disease home treatments (HRT) not captured in currently available Patient-Reported Outcome Measures (PROM). We present psychometric validation Experience Measure (PREM) 'HowRwe' Spanish for HRT.
<h3>Background</h3> Atypical femoral fractures (AFF) are an infrequent side-effect of the antiosteoporotic treatment with bisphosphonates (around 5/10,000 patients/year). AFF usually occur at sites suffering tensional stress, such as subtrochanteric or diaphyseal femur. The pathogenic mechanism is not well known. Bisphosphonates (BPs) inhibit osteoclast activity and reduce bone remodelling, leading to a loss auto-repair tissue capacity causing effects that can contribute AFF. Denosumab...
Purpose: The prevalence of Chronic obstructive pulmonary disease (COPD) in Spain has been evaluated the last ten years by EPISCAN 2007 and II 2017. This study describes changes COPD an urban region 10 years, its risk factors underdiagnosis. Patients Methods: Participants from Autonomous Community Madrid (Spain) were selected both studies up to age 80 years. A descriptive analysis their sociodemographic clinical characteristics, as well gender, was conducted. defined a post-bronchodilator...