- Nanoparticle-Based Drug Delivery
- RNA modifications and cancer
- Glycosylation and Glycoproteins Research
- Cancer-related molecular mechanisms research
- Macrophage Migration Inhibitory Factor
- Epigenetics and DNA Methylation
- Prostate Cancer Treatment and Research
- Cancer-related gene regulation
- Advanced Nanomaterials in Catalysis
- Ubiquitin and proteasome pathways
- Monoclonal and Polyclonal Antibodies Research
- Hepatocellular Carcinoma Treatment and Prognosis
- MicroRNA in disease regulation
- Protein purification and stability
- Nanoplatforms for cancer theranostics
Ningbo No. 2 Hospital
2024
Zhengzhou People's Hospital
2016
The aim of the present study was to construct a single-chain bispecific antibody (scBsAb) against cervical carcinoma and investigate its biological activities. scBsAb constructed using genetic cloning technique antigen binding activities were detected by ELISA. iodogen method used analyze pharmacokinetics. Rosette formation test detect ability between peripheral blood lymphocytes (PBLs) Cs1213 cancer cells. In addition, MTT performed killing effect PBLs. molecular weight ~60 kDa. scBsAbs...
Background and Objectives Tripartite motif-containing protein 50 (TRIM50) is a recently discovered E3 ubiquitin ligase that participates in tumor progression. TRIM50 overexpressed many cancers, although few studies focused on TRIM50's role breast cancer.