Siobhan Botwright

ORCID: 0000-0002-8204-2065
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Vaccine Coverage and Hesitancy
  • Health Policy Implementation Science
  • Health Systems, Economic Evaluations, Quality of Life
  • Substance Abuse Treatment and Outcomes
  • Pharmaceutical Practices and Patient Outcomes
  • COVID-19 epidemiological studies
  • Innovation and Socioeconomic Development
  • SARS-CoV-2 and COVID-19 Research
  • Viral gastroenteritis research and epidemiology
  • Opioid Use Disorder Treatment
  • Healthcare cost, quality, practices
  • Global Maternal and Child Health
  • Viral Infections and Outbreaks Research
  • Immune responses and vaccinations
  • Clinical practice guidelines implementation
  • Public-Private Partnership Projects
  • COVID-19 Impact on Reproduction
  • Mechanical Circulatory Support Devices
  • Child Nutrition and Water Access
  • COVID-19 Clinical Research Studies
  • Vibrio bacteria research studies
  • Chronic Disease Management Strategies
  • Bacterial Infections and Vaccines
  • Hepatitis Viruses Studies and Epidemiology
  • Cervical Cancer and HPV Research

Health Intervention and Technology Assessment Program
2021-2024

University of Strathclyde
2024

Ministry of Public Health
2022-2024

World Health Organization
2020-2023

World Health Organization - Pakistan
2021

Gavi
2017

Several economic obstacles can deter the development and use of vaccines. This lead to limited product options for some diseases, delays in new development, inequitable access Although seemingly distinct, these are actually interrelated therefore need be addressed through a single over-arching strategy encompassing all stakeholders.To help overcome obstacles, we propose approach, Full Value Vaccines Assessments (FVVA) framework, guide assessment communication value vaccine. The FVVA...

10.1186/s12916-023-02929-0 article EN cc-by BMC Medicine 2023-07-04

From 2012 to 2016, Gavi, the Vaccine Alliance, provided support for countries conduct small-scale demonstration projects introduction of human papillomavirus vaccine, with aim determining which vaccine delivery strategies might be effective and sustainable upon national scale-up. This study reports on operational costs cost determinants different vaccination within these across twelve using a standardized micro-costing tool. The World Health Organization Cervical Cancer Prevention Control...

10.1371/journal.pone.0182663 article EN public-domain PLoS ONE 2017-10-10

Objectives: The optimal development, use and impact of vaccines can be hindered by a number seemingly distinct, but interrelated obstacles, which need to addressed with single over-arching strategy encompassing all stakeholders. Methods: We propose framework on the Full Value Vaccines Assessments (FVVA) guide assessment communication value vaccines, facilitate alignment among key stakeholders, improve decision-making around investment in vaccine policy, procurement, introduction, for...

10.2139/ssrn.3841999 article EN SSRN Electronic Journal 2021-01-01

Innovations in vaccine product attributes could play an important role addressing coverage and equity (C&E) gaps, but there is currently a poor understanding of the full system impact trade-offs associated with investing such technologies, both from perspective national immunisation programmes (NIPs) developers. Total Systems Effectiveness (TSE) was developed as approach to evaluate vaccines different systems perspective, order analyse compare value innovative products settings. The TSE has...

10.1016/j.jvacx.2020.100078 article EN cc-by Vaccine X 2020-10-06

Background: The World Health Organization (WHO) has developed the Total System Effectiveness (TSE) framework to assist national policy-makers in prioritizing vaccines. pilot was launched Thailand explore potential use of TSE a country with established governance structures and accountable decision-making processes for immunization policy. While existing literature informs vaccine adoption decisions GAVI-eligible countries, this study attempts address gap by examining policy process non-GAVI...

10.15171/ijhpm.2020.01 article EN cc-by International Journal of Health Policy and Management 2020-01-20

Background Despite a growing global commitment to universal health coverage, considerable vaccine coverage and uptake gaps persist in resource-constrained settings. One way of addressing the is by ensuring product innovation relevant responsive needs these contexts. Total Systems Effectiveness (TSE) framework has been developed characterize preferred attributes from perspective country decision-makers inform research development (R&D) products. A proof concept pilot study took place Thailand...

10.1371/journal.pone.0233950 article EN cc-by PLoS ONE 2020-06-10

Background The durability of heterologous COVID-19 vaccine effectiveness (VE) has been primarily studied in high-income countries, while evaluation policies low- and middle-income countries remains limited. Objective We aimed to evaluate the duration during which VE regimens mitigating serious outcomes, specifically severe death following hospitalization with COVID-19, over 50%. Methods formed a dynamic cohort by linking records Thai citizens aged ≥18 years from citizen vital, vaccine, cases...

10.2196/48255 article EN cc-by JMIR Public Health and Surveillance 2024-03-05

Abstract Objectives Health technology assessment (HTA) guidelines are intended to support the successful implementation of HTA by enhancing consistency and transparency in concepts, methods, processes, use, thereby legitimacy decision-making process. This report lays out good practices practical recommendations for developing or updating ensure implementation. Methods The task force was established 2022 comprised experts academics from various geographical regions, each with substantial...

10.1017/s0266462324004719 article EN International Journal of Technology Assessment in Health Care 2024-01-01

Abstract Background Alcohol use is one of the leading risk factors for premature death and disability. Screening, brief interventions referral to treatment, as well evidence-based psychosocial pharmacological interventions, are important in reducing burden harmful alcohol use. While many reviews summarise evidence specific or populations, there has yet be a comprehensive comparison interventions. As such, this umbrella review aims identify effective prevention treatment use, with...

10.21203/rs.3.rs-1233643/v1 preprint EN cc-by-nc-sa Research Square (Research Square) 2022-06-02

This study aimed to assess the cost-effectiveness of introducing universal maternal pertussis immunisation under national vaccine programme in Thailand. We conducted a cost-utility analysis from societal perspective compare vaccination with (1) TdaP vaccine, (2) Td and aP (3) only. constructed two decision-tree models Markov elements, each following different clinical pathway, allow us examine structural uncertainty. Costs were converted 2021 Thai Baht (THB) discount rate 3% was applied...

10.1007/s40273-022-01207-w article EN cc-by-nc PharmacoEconomics 2022-11-09

<sec> <title>BACKGROUND</title> The durability of heterologous COVID-19 vaccine effectiveness (VE) has been primarily studied in high-income countries, while evaluation policies low- and middle-income countries remains limited. </sec> <title>OBJECTIVE</title> We aimed to evaluate the duration during which VE regimens mitigating serious outcomes, specifically severe death following hospitalization with COVID-19, over 50%. <title>METHODS</title> formed a dynamic cohort by linking records Thai...

10.2196/preprints.48255 preprint EN 2023-04-17

<h3>Objectives</h3> Immunization programs in low-income and middle-income countries (LMICs) are faced with an ever-growing number of vaccines public health importance recommended by the World Health Organization, while also financing a greater proportion program through domestic resources. More than ever, national immunization must be equipped to contextualize global guidance make choices that best suited their setting. The CAPACITI decision support tool has been developed collaboration...

10.1136/bmjgh-2022-isph.79 article EN cc-by-nc Abstracts 2022-04-01

Abstract Background This study aimed to identify targeted interventions for the prevention and treatment of harmful alcohol use. Umbrella review methodology was used summarise effectiveness across a broad range interventions, in order which should be considered inclusion within universal health coverage schemes low- middle-income countries. Methods findings We included systematic reviews with meta-analysis randomised controlled trials (RCTs) on addressing use drinkers or individuals...

10.21203/rs.3.rs-2031752/v1 preprint EN cc-by-nc-sa Research Square (Research Square) 2022-09-22
Coming Soon ...