- Health and Lifestyle Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Obesity, Physical Activity, Diet
- Cardiovascular Function and Risk Factors
- Influenza Virus Research Studies
- Respiratory viral infections research
- Tuberculosis Research and Epidemiology
- Heart Failure Treatment and Management
- HIV/AIDS Research and Interventions
- Adolescent and Pediatric Healthcare
- HIV Research and Treatment
- COVID-19 epidemiological studies
- Immunodeficiency and Autoimmune Disorders
- Cardiac pacing and defibrillation studies
- Nursing Roles and Practices
- Clostridium difficile and Clostridium perfringens research
- HIV, Drug Use, Sexual Risk
- Immune Cell Function and Interaction
- HIV/AIDS drug development and treatment
- Cardiovascular Disease and Adiposity
- Virology and Viral Diseases
- Athletic Training and Education
- Congenital Heart Disease Studies
- Vaccine Coverage and Hesitancy
- HIV-related health complications and treatments
National Coalition of STD Directors
2024
Cambridge Quantum Computing (United Kingdom)
2024
Lung Institute
2023
The Ohio State University
2023
Veterans Health Administration
2016-2019
National Institute of Allergy and Infectious Diseases
2018
National Institutes of Health
2018
BackgroundSince the 1918 influenza pandemic, non-randomised studies and small clinical trials have suggested that convalescent plasma or anti-influenza hyperimmune intravenous immunoglobulin (hIVIG) might benefit for patients with infection, but definitive data do not exist. We aimed to evaluate safety efficacy of hIVIG in a randomised controlled trial.MethodsThis randomised, double-blind, placebo-controlled trial was planned 45 hospitals Argentina, Australia, Denmark, Greece, Mexico, Spain,...
To compare disease progression and mortality between women men infected with human immunodeficiency virus (HIV).Multicenter cohort.Seventeen community-based centers participating in the Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA).A total of 768 3779 enrolled one or more 11 protocols September 7, 1990, 30, 1993.Survival opportunistic events.The median CD4+ cell count at enrollment into cohort was 0.240 x 10(9)/L (240/microL) 0.137 (P < .001). Compared men, were...
Background: Evidence from prospectively designed studies to guide on-site monitoring practices for randomized trials is limited. A cluster study, nested within the Strategic Timing of AntiRetroviral Treatment (START) trial, was conducted evaluate monitoring. Methods: Sites were either annual or no All sites centrally monitored, and local carried out twice each year. Randomization stratified by country projected enrollment in START. The primary outcome a participant-level composite including...
Abstract Background Both human immunodeficiency virus (HIV) infection and antiretroviral therapy (ART) may increase cardiovascular disease (CVD) risk. Vascular function assessments can be used to study CVD pathogenesis. We compared the effect of immediate versus deferred ART initiation at CD4 counts &gt;500 cells/mm3 on small arterial elasticity (SAE) large artery (LAE). Methods Radial blood pressure waveforms were recorded noninvasively. Small LAE derived from analysis diastolic pulse...
Early clinical severity assessments during the 2009 influenza A H1N1 pandemic (pH1N1) overestimated due to selection bias and other factors. We retrospectively investigated how use data from International Network for Strategic Initiatives in Global HIV Trials, a global research network, make more accurate case fatality ratio (CFR) estimates early future pandemic, an essential part of response. estimated CFR medically attended (CFRMA) as product probability hospitalization given confirmed...
OBJECTIVE: To assess the prevalence of tuberculosis (TB) or a positive skin test in healthcare workers (HCWs) providing services to human immunodeficiency virus (HIV)-infected individuals and determine prospectively incidence new infections this population.DESIGN: This prospective cohort study enrolled 1,014 HCWs working with HIV-infected populations from 10 metropolitan areas.Purified protein derivative (PPD) tuberculin tests were placed at baseline every 6 months afterwards on those...
Abstract OBJECTIVE: To assess the prevalence of tuberculosis (TB) or a positive skin test in healthcare workers (HCWs) providing services to human immunodeficiency virus (HIV)-infected individuals and determine prospectively incidence new infections this population. DESIGN: This prospective cohort study enrolled 1,014 HCWs working with HIV-infected populations from 10 metropolitan areas. Purified protein derivative (PPD) tuberculin tests were placed at baseline every 6 months afterwards on...
The Humberside Enhanced Resettlement Service (HERS) was a psychologically informed, supported accommodation service for people on probation whose presentation is consistent with personality disorder. An evaluation, utilising semi-structured interviews, identified four themes of experience and their practitioners who worked HERS: (1) relationships; (2) practical support; (3) expectations, (4) risk. This suggested that providing led enhances therapeutic relationships between professionals...
Abstract Background The 2022 mpox outbreak disproportionately affected gay, bisexual, and other men who have sex with (GBMSM). Mpox cases continue to be reported nationally. Vaccination is a tool prevent the spread of serious disease from mpox. To understand vaccine uptake hesitancy, virtual focus group unvaccinated GBMSM was conducted. Methods In November 2022, 60-minute, conducted within an artificial intelligence (AI) platform that engages participants in chat-based conversation. AI...
To develop a digital platform to conduct family-based, dilated cardiomyopathy (DCM) genetic research.
To develop a digital platform to conduct family-based, dilated cardiomyopathy (DCM) genetic research.