- Ocular Diseases and Behçet’s Syndrome
- Ocular Infections and Treatments
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Cerebral Venous Sinus Thrombosis
- Ophthalmology and Eye Disorders
- Retinal and Optic Conditions
- Retinal Diseases and Treatments
- Chronic Lymphocytic Leukemia Research
- Traumatic Ocular and Foreign Body Injuries
- Actinomycetales infections and treatment
- Peripheral Neuropathies and Disorders
- Drug-Induced Ocular Toxicity
- Retinal Development and Disorders
- Porphyrin Metabolism and Disorders
- Central Venous Catheters and Hemodialysis
- Ocular Surface and Contact Lens
- Gastroesophageal reflux and treatments
- Nasolacrimal Duct Obstruction Treatments
- Pediatric health and respiratory diseases
- Cell Adhesion Molecules Research
- Bacterial Identification and Susceptibility Testing
- Retinoids in leukemia and cellular processes
- Lanthanide and Transition Metal Complexes
- Obstructive Sleep Apnea Research
University Hospital Southampton NHS Foundation Trust
2021-2024
Salisbury University
2024
NIHR Southampton Biomedical Research Centre
2022-2024
Salisbury NHS Foundation Trust
2024
Salisbury District Hospital
2024
National Health Service
2023
University Hospitals Dorset NHS Foundation Trust
2022
Queen Alexandra Hospital
2022
Royal Bournemouth Hospital
2020
University Hospitals Plymouth NHS Trust
2018
An 82-year-old man with a history of herpes simplex keratitis 40 years previously presented recurrence, 1 day following vaccination for novel COVID-19. His condition worsened despite topical treatment ganciclovir gel. A diagnosis herpetic stromal was made, requiring systemic aciclovir, prednisolone, moxifloxacin and atropine, oral doxycycline. He improved clinically on treatment, some residual corneal scarring. Visual acuity from 6/36 corrected at presentation, to 6/24 treatment. Clearly,...
Drug-induced uveitis is a rare but important subgroup of particularly among newer drugs in the market. Establishing diagnosis can be challenging and requires physician to have high index suspicion holistic approach with consideration being afforded history, clinical examination, investigations. In this case report, we describe hypopyon 64-year-old male background myelofibrosis for which he was started on fedratinib. A thorough negative investigation panel, temporal association between start...
A 71-year-old woman presented 2 weeks after vaccination with the first dose of Vaxzevria (AstraZeneca, Oxford) for COVID-19 a left lower motor neuron facial nerve palsy, which progressed to bilateral involvement. This was accompanied by proximal leg weakness. She diagnosed 'facial diplegia paraesthesia' variant Guillain-Barré syndrome. Seven post she developed painless loss vision in right eye. The visual acuity that eye light perception only relative afferent pupillary defect and optic disc...
Background Acute acquired concomitant esotropia (AACE) is usually a benign form of strabismus that infrequently associated with intracranial pathology. Clinicians have noted an increase in its incidence and theorize it may be related to public health "lockdown" measures taken response the COVID-19 pandemic. With increased AACE clinicians must firstly differentiate from common accommodative secondly recognize as possible sign serious neuropathology.Diffuse Intrinsic Pontine Glioma (DIPG)...
Background Deep sclerectomy (DS) is a non-penetrating surgical procedure for glaucoma, reducing the resistance to aqueous outflow and lowering intraocular pressure while maintaining physiological barrier between anterior chamber sub-scleral space. This offers lower complication profile than penetrating procedures, though with less (IOP) reduction. Methods We retrospectively reviewed electronic record all DS undertaken at our hospital (a tertiary care center) over 14 years, collecting data on...
Abiotrophia defectiva is a fastidious organism that has been implicated in severe infections such as endocarditis immunocompetent patients. Modern tools are available to aid identification, but the main challenge remains clinical suspicion of A. .An otherwise fit and well 65-year-old female presented with reduced vision, red eye discomfort 2 days following routine left cataract surgery. She had visual acuity light perception only, significant anterior chamber inflammation (including...
Purple urine bag syndrome is an unusual condition that heralds underlying urinary tract infection, in which certain bacteria produce a purple discolouration within the catheter of affected cases. It most often seen elderly women with constipation. While alarming, it can be resolved by treating infection causing it. This report presents patient who developed while inpatient, and discusses pathogenesis behind condition.
The OMNI surgical system allows for 360° canaloplasty and trabeculotomy patients with glaucoma, either as a standalone procedure or in combination cataract surgery. There is currently limited evidence on its use forms of angle-closure though other microinvasive glaucoma surgeries have been used. We present three angle closure who underwent the procedure.
Alport syndrome, a rare genetic condition, can manifest various ocular abnormalities. This case report presents unique instance of syndrome where bilateral reduced visual acuity led to cataract surgery and subsequent central serous chorioretinopathy due steroid treatment. By utilizing multiple imaging modalities, we aim illustrate classical atypical findings, addressing literature gap sharing our experience for educational purposes.
Leukaemic optic neuropathy is an uncommon cause of visual loss which represents a neuro-oncological emergency with the potential irreversible blindness if untreated. It can be difficult to diagnose, often presenting normal neuroradiological and cerebrospinal fluid findings. We present case 26-year-old woman T-cell acute lymphoblastic leukaemia secondary leukaemic infiltration, who demonstrated features on optical coherence tomography that aided diagnosis this condition. This included...
A female patient with previous vitrectomy for epiretinal membrane in the left eye underwent bilateral selective laser trabeculoplasty (SLT) pigmentary glaucoma and subsequently developed cystoid macular oedema (CMO) vitrectomised eye. This resolved fully treatment topical steroids non-steroidal anti-inflammatory drug (NSAID) drops. complication has been very rarely reported literature, a subsequent internal audit found low rate of CMO temporally related to SLT 0.07%. We suggest close...
A woman aged 69 years presented with a 2-week history of left-sided neck swelling, dysphagia and night sweats. CT revealed an internal jugular venous thrombosis, multiple pulmonary emboli gastric thickening. Endoscopy found haemorrhagic fundal polypoidal tumour; biopsies diagnosed adenocarcinoma, Lauren's intestinal type. She was managed radiotherapy low molecular weight heparin.
Necrotising scleritis is a rare, inflammatory condition with potentially devastating visual consequences. It can be associated and infectious causes, has been linked to several different ocular procedures. We present difficult case of patient surgically-induced necrotising following routine phacoemulsification cataract surgery, who developed secondary Nocardia bacterial infection. He required number surgical interventions prolonged antibiotic therapy, suffering recurrent scleral abscesses. A...
Background Neodymium-doped yttrium aluminium garnet (Nd:YAG) posterior capsulotomy is a common treatment for capsular opacification. Practice varies regarding routine follow-up. In this study, we reviewed follow-up rates and treatment-related complications from district general hospital's ophthalmology unit to assess areas improvement cost-effectiveness. Methodology We conducted retrospective review of electronic patient records all patients treated with Nd:YAG in 2019 at our hospital....
Bacterial endophthalmitis describes inflammation of the vitreous secondary to bacterial colonisation. It is an ophthalmic emergency requiring prompt treatment increase chance preserving sight and saving eye. categorised as exogenous or endogenous in origin. Endogenous rare, resulting from haematogenous spread bacteria systemic infection. Exogenous endophthalmitis, however, results introduction ocular surface external source into This can occur post-operatively, following a penetrating...