- Obesity, Physical Activity, Diet
- Birth, Development, and Health
- Diabetes Management and Research
- Maternal Mental Health During Pregnancy and Postpartum
- Prenatal Substance Exposure Effects
- Physical Activity and Health
- Cardiovascular Health and Risk Factors
- Homelessness and Social Issues
- Gestational Diabetes Research and Management
- Urban Transport and Accessibility
- Health, Environment, Cognitive Aging
- Health and Lifestyle Studies
- Mental Health and Patient Involvement
- Total Knee Arthroplasty Outcomes
- Diabetes and associated disorders
- Cardiovascular and exercise physiology
- Orthopaedic implants and arthroplasty
- Diabetes Management and Education
- Heart Rate Variability and Autonomic Control
- Substance Abuse Treatment and Outcomes
- Hip and Femur Fractures
- Streptococcal Infections and Treatments
- Behavioral Health and Interventions
- Ethics in medical practice
- Nutritional Studies and Diet
University of Manitoba
2019-2024
Children's Hospital Research Institute of Manitoba
2019-2024
University of British Columbia
2023
Skeletal muscle atrophy, dysfunction, and fatigue are important complications of chronic obstructive pulmonary disease (COPD). Greater reliance on glycolytic metabolism increased type III/IV afferent activity increase ventilatory drive, promote constraint, amplify exertional dyspnea, limit exercise tolerance. To investigate whether muscular adaptation with resistance training (RT) could improve tolerance, intrinsic neuromuscular fatigability in individuals COPD (n = 14, FEV1 62 ± 21%...
Abstract Objective To determine if expansion of multi-use physical activity trails in an urban centre is associated with reduced rates cardiovascular disease (CVD). Methods This was a natural experiment difference differences analysis using administrative health records and trail-based cycling data Winnipeg, Canada. Prior to the intervention, each year, 314,595 (IQR: 309,044 319,860) persons over 30 years without CVD were comparison group 37,901 residents 37,213 38,488) intervention group....
Background: Very few experimental studies exist describing the effect of changes to built environment and opportunities for physical activity (PA). We examined impact an urban trail created on a frozen waterway visitor counts PA levels. Methods: studied natural experiment in Winnipeg, Manitoba, Canada that included 374,204 237,362 users during 2017/2018 2018/2019 winter seasons. The intervention was 10 km lasting 8–10 weeks. comparator conditions were time periods immediately before after...
Introduction: There is little information describing rates of gestational diabetes (GDM) over the last two decades among population sub-groups, particularly within an urban context. Hypotheses: Rates GDM will increase time, rural dwelling women and those living in low socio-economic neighbourhoods. Research Design Methods: We performed a registry-based administrative cohort study that delivered child between 2000 and-2019 (n = 293 514) entire province Manitoba, Canada. was defined as...
Aspects of the built environment that support physical activity are associated with better population health outcomes. Few experimental data exist to these observations. This protocol describes study creation urban trials on cardiovascular disease (CVD)-related morbidity and mortality in a large centre. Between 2008 2010, city Winnipeg, Canada, four, paved, multiuse (eg, cycling, walking running), two-lane trails 5-8 km long span ~60 neighbourhoods. Linking population-based census...
Objectives: Examine the relationship between maternal pre-pregnancy body mass index (BMI) and offspring systolic blood pressure (SBP) at 18 yrs old. Methods: We performed multivariate regression causal mediation analysis within 3700 mother - pairs from a prospective birth cohort. The main exposure was BMI categorized as healthy weight, overweight, or obese according to international criteria. outcomes were high-normal BP hypertension defined SBP 90-95 th centile >95 for height sex years,...
ABSTRACT Importance Hypertension is the second most common pediatric chronic disease in Westernized countries. Understanding natural history of hypertension key to identifying prevention strategies. Objective Examine relationship between maternal pre-pregnancy body mass index (BMI) and offspring blood pressure at 18 years mediating role growth throughout childhood adolescence. Design, Setting, Participants We performed multivariable regression causal mediation analyses within 3217 mother -...
To understand the postoperative acute-care physiotherapy course for First Nations people returning after total hip replacement (THR) to remote communities with limited rehabilitation services and evaluate length of stay attainment functional milestones THR determine what extent an urban-based clinical pathway is transferrable effective patients in a rural setting.Data were collected retrospectively by reviewing charts who underwent Northwest Ontario catchment area from 2007 through 2012.For...
Objective: We previously found that exposure to adverse childhood experiences (ACEs) is associated adolescent obesity. This study was designed identify mediators of this association. hypothesized before 9 yrs would be with an increased risk obesity at 18 yrs, and behavioural emotional factors mediate Methods: In 2007/2008, 8568 nine-year-olds were randomly sampled, enrolled in the Growing up Ireland cohort followed yrs. The main exposures 14 including four traditional ACEs years age,...
Background: Hypertension is the second most common pediatric chronic disease in Westernized countries. Understanding natural history of hypertension key to identifying prevention strategies. The present study will examine relationship between maternal pre-pregnancy body mass index (BMI) and possible mediating role growth throughout childhood adolescence on offspring blood pressure at 18 years.Methods: We performed multivariable regression causal mediation analyses within 3217 mother - pairs...
Introduction: There is little experimental evidence of the impact multi-use recreational trails that support physical activity on cardiovascular disease (CVD). Hypothesis: Neighbourhoods added would experience a greater decline in CVD events and risk factors compared to neighbourhoods did not. Methods: We used difference differences design study addition four 4-7km length CVD-related outcomes using administrative health, census built environment data available for all citizens 30 years age...