A5082944655- Silk-based biomaterials and applications
- Invertebrate Immune Response Mechanisms
- Biochemical and Structural Characterization
- Genomics and Phylogenetic Studies
- Insect symbiosis and bacterial influences
- Genetic Mapping and Diversity in Plants and Animals
- Chromosomal and Genetic Variations
- Silkworms and Sericulture Research
- Olfactory and Sensory Function Studies
- Insect Resistance and Genetics
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Genetics, Aging, and Longevity in Model Organisms
- Biochemical Analysis and Sensing Techniques
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Venomous Animal Envenomation and Studies
- Advanced Chemical Sensor Technologies
- Animal Behavior and Reproduction
South China Normal University
2020-2025
Sun Yat-sen University
2024
Eye & ENT Hospital of Fudan University
2024
Key Laboratory of Guangdong Province
2022
Sichuan Agricultural University
2015
Our recent investigations on the function of Drosophila CG11700 and CG32744 (Ubi-p5E) genes using CRISPR/Cas9 deletion technology could not repeat or confirm results shown in our previous study which was based P-element excision assay (Zhan et al. 2012). Here by editing, we generated mutants with whole gene body fully deleted from genome, truncated N-terminal 103 aa out its total 301 peptide sequence. We carefully conducted male fecundity found that offsprings mutant were significantly more...
Abstract Background The black widow spider has both extraordinarily neurotoxic venom and three-dimensional cobwebs composed of diverse types silk. However, a high-quality reference genome for the was still unavailable, which hindered deep understanding application valuable biomass. Findings We assembled Latrodectus elegans genome, including size 1.57 Gb with contig N50 4.34 Mb scaffold 114.31 Mb. Hi-C scaffolding assigned 98.08% to 14 pseudo-chromosomes, BUSCO, completeness analysis revealed...
Early domestication and the following improvement are two important processes in cocoon silk evolution of silkworms. In contrast to early domestication, understanding process is still fuzzy. By systematically comparing larval gland transcriptomes wild, domestic, improved silkworms, we highlighted a novel landscape transcriptome glands ones. We first clarified that protein genes were up-regulated modern breeding but not domestication. Furthermore, found differentially expressed (DEGs) between...