Edgar Fischer

ORCID: 0000-0002-8238-3134
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About
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Research Areas
  • Optical Wireless Communication Technologies
  • Semiconductor Lasers and Optical Devices
  • Advanced Measurement and Metrology Techniques
  • Adaptive optics and wavefront sensing
  • Advanced Optical Sensing Technologies
  • Satellite Communication Systems
  • Optical measurement and interference techniques
  • Ovarian cancer diagnosis and treatment
  • Renal Diseases and Glomerulopathies
  • Optical Systems and Laser Technology
  • Cell Adhesion Molecules Research
  • Metastasis and carcinoma case studies
  • Advanced Fiber Optic Sensors
  • Endometrial and Cervical Cancer Treatments
  • Infectious Disease Case Reports and Treatments
  • Sarcoma Diagnosis and Treatment
  • Renal cell carcinoma treatment
  • Lymphoma Diagnosis and Treatment
  • Spacecraft Design and Technology
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Cancer and Skin Lesions
  • Optical Network Technologies
  • Abdominal vascular conditions and treatments
  • Blood Coagulation and Thrombosis Mechanisms
  • Advanced MEMS and NEMS Technologies

University of New Mexico
2014-2024

University of Iowa
2014

Pennsylvania State University
2014

Gynecologic Oncology Group
2014

University of Oklahoma
2014

University of Iowa Hospitals and Clinics
2014

Fox Chase Cancer Center
2014

Case Western Reserve University
2014

Massachusetts General Hospital
2014

Penn State Milton S. Hershey Medical Center
2014

10.1007/bf00626630 article DE The Science of Nature 1948-01-01

Tissue factor (TF), the protease receptor initiating coagulation system, functions in vascular development, angiogenesis, and tumor cell metastasis by poorly defined molecular mechanisms. We demonstrate that immobilized ligands for TF specifically support adhesion, migration, spreading, intracellular signaling, which are not inhibited RGD peptides. Two-hybrid screening identified actin-binding protein 280 (ABP-280) as ligand cytoplasmic domain. Extracellular ligation of is necessary ABP-280...

10.1083/jcb.140.5.1241 article EN The Journal of Cell Biology 1998-03-09

ABSTRACT Two biocontrol agents, a yeast (Pichia guilermondii) and bacterium (Bacillus mycoides), were tested separately together for suppression of Botrytis cinerea on strawberry leaves plants. Scanning electron microscopy revealed significant inhibition conidial germination in the presence Pichia guilermondii, whereas Bacillus mycoides caused breakage destruction conidia. When both agents applied mixture, was more severe. The modes action each elucidated relative quantitative contribution...

10.1094/phyto.2002.92.9.976 article EN other-oa Phytopathology 2002-09-01

Anti-glomerular basement membrane (anti-GBM) glomerulonephritis is a rare disease caused by IgG autoantibodies against the glomerular membrane. We describe clinical and pathologic findings in series of renal biopsy specimens from 80 patients. The patients ranged age 16 to 87 years. distribution was bimodal, with one peak at young predominated males second sixth eighth decades females predominating. Most (70 [88%]) had severe necrotizing crescents more that 50% glomeruli. fraction crescentic...

10.1309/nptp4ukv7ju3elmq article EN American Journal of Clinical Pathology 2006-03-01

10.1038/modpathol.3800634 article EN publisher-specific-oa Modern Pathology 2006-01-01

Tesat together with Synopta have built a Transportable Adaptive Optical Ground Station (TAOGS) under contract of German Aerospace Center DLR for communication the 1<sup>st</sup> and 2<sup>nd</sup> generation Tesat's spaceborne Laser Communication Terminals (LCTs), which employ coherent homodyne optical 1064 nm binary phase shift keying (BPSK) modulation. The TAOGS is able to communicate space segments on low earth orbit (LEO, high pointing tracking dynamics, 5.625 Gbps), geostationary (GEO,...

10.1117/12.2218275 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2016-03-15

Progestins have been used in the treatment of recurrent endometrial adenocarcinoma for almost 50 yr. Some carcinomas respond to hormonal therapy, but mechanism action remains incompletely known. We wished determine efficacy progestins induce a histologic response endometrioid and explore its effects on immunohistochemical measures growth cell death. The Gynecologic Oncology Group initiated study 75 women with adenocarcinoma, 59 whom received progestin, medroxyprogesterone acetate 21 24 d...

10.1097/pgp.0000000000000177 article EN International Journal of Gynecological Pathology 2014-10-01

Two-wavelength double heterodyne interferometry is applied for topographic measurements on optically rough target surfaces. A two-wavelength He–Ne laser and a matched grating technique are used to improve system stability simplify frequency generation.

10.1364/ao.30.003139 article EN Applied Optics 1991-08-01

Prostate field cancerization denotes molecular alterations in histologically normal tissues adjacent to tumors. Such include deregulated protein expression, as we have previously shown for the key transcription factor early growth response 1 (EGR-1) and lipogenic enzyme fatty acid synthase (FAS). Here add two secreted factors macrophage inhibitory cytokine (MIC-1) platelet derived A (PDGF-A) growing list of markers prostate cancerization. Expression MIC-1 PDGF-A was measured quantitatively...

10.1371/journal.pone.0119314 article EN cc-by PLoS ONE 2015-03-13

In this paper we present the setup including optics and components, reconstruction scheme performance measurements of adaptive (AO) system implemented at 26 cm transportable optical ground station (TAOGS) which is presently located Observatorio del Teide, Tenerife. The used to improve signal-to-noise ratio satellite laser communications. It operates with coherent communication systems 1064nm. wavefront sensor an 96-element Shack-Hartmann-sensor (11 sub-apertures across pupil), matched a...

10.1109/icsos.2015.7425071 article EN 2015-10-01

Primary ovarian small cell carcinomas are rare tumors that subclassified into the hypercalcemic (HT) and pulmonary type (PT), each tumor has different clinicopathologic characteristics. However, overlapping morphologic features can make distinction between these lesions difficult. The PT carcinoma is very rare, with only one series a few case reports published. authors report two additional cases of this entity also for first time immunohistochemical finding perinuclear dot-like staining...

10.1097/01.pai.0000155796.49278.62 article EN Applied immunohistochemistry & molecular morphology 2006-06-01

Telomere attrition occurs early in the development of prostatic adenocarcinoma. However, little is known about either telomere status benign hyperplasia (BPH), or spatial and organ-wide distribution potential aberrations throughout all areas glands affected by cancer BPH.Slot blot titration assay was used to determine DNA content (TC), a proxy for length, macrodissected tissue consisting 54 normal samples from 5 disease-free prostates, 128 BPH 4 non-cancerous 45 tumor, 73 BPH,...

10.1002/pros.21182 article EN The Prostate 2010-04-29

10.1007/bf01377808 article DE The European Physical Journal A 1961-04-01

We present a case of rapidly progressive pseudomembranous tracheobronchitis and pneumonia in 52-year-old woman with severe aplastic anemia. Bacillus cereus was isolated from bronchoalveolar lavage fluids, blood cultures, pseudomembrane biopsy specimens; despite intensive antibiotic treatment, the patient's condition deteriorated rapidly. To our knowledge, this is first report B. infection that has caused tracheobronchitis, possibly because production bacterial toxins.

10.1086/322674 article EN Clinical Infectious Diseases 2001-09-01
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