A5034596398- Traumatic Brain Injury Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Automotive and Human Injury Biomechanics
- Cardiac Arrest and Resuscitation
- Traumatic Ocular and Foreign Body Injuries
- Genetic Neurodegenerative Diseases
Virginia Tech
2022-2024
University of California, San Diego
2024
This is a protocol to describe the materials and methods utilized perform splash test for assessment of grooming behaviors as measure self-care in adult rats. The uses an atomized spray bottle coat animal’s back fur 10% sucrose solution before being placed into small testing box observation behaviors. Alterations total time spent grooming, frequency bouts, or latency begin may suggest depression-like behavior compulsive-like behavior, depending on directionality behavioral alterations....
This is a protocol to describe the materials and methods utilized perform preclinical traumatic brain injury (TBI) using closed-head controlled impact model in adult rats. The utilizes an electromagnetic actuator deliver intact scalp has been optimized for use A skull template used mark site parameters can be adjusted according desired severity of control box. posting this part mission PREClinical Interagency reSearch resourcE-TBI (PRECISE-TBI, precise-tbi.org) improve clinical translation...
Free-field blast exposure imparts a complex, dynamic response within brain tissue that can trigger cascade of lasting neurological deficits. Full body mechanical and physiological factors are known to influence the body's adaptation this seemingly instantaneous insult, making it difficult accurately pinpoint injury mechanisms. This study examined intracranial pressure (ICP) profile characteristics in rat model as function overpressure magnitude location. Metrics such peak rate change...