A5090715178- Cytokine Signaling Pathways and Interactions
- Dermatology and Skin Diseases
- Rheumatoid Arthritis Research and Therapies
- Vasculitis and related conditions
- Systemic Lupus Erythematosus Research
- Immune Cell Function and Interaction
First Affiliated Hospital of Kunming Medical University
2021
Kunming Medical University
2021
Wuhan University
2021
Renmin Hospital of Wuhan University
2021
Background. Osteoarthritis (OA) and rheumatoid arthritis (RA) are well-known cause of joint disability. Although they have shown the analogous clinical features involving chronic synovitis that progresses to cartilage bone destruction, pathogenesis initiates perpetuates synovial lesions between RA OA remains elusive. Objective. This study is aimed at identifying disease-specific hub genes, exploring immune cell infiltration, elucidating underlying mechanisms associated with lesion. Methods....
Immunoglobulin A vasculitis (IgAV), previously known as Henoch-Schönlein purpura, is the most common that has a classical skin manifestation of palpable purpuric rash. Factors pertinent to IgAV remain inadequately understood. Here, we aimed examine gut microbiome shifts associated with and its recovery.Stool samples were collected from 10 children (6-14 years old) before after multi-drug therapy, along 9 age-matched healthy children. The subjected metagenomic analyses investigate taxonomic...