A5101850193- Quantum Information and Cryptography
- Quantum Computing Algorithms and Architecture
- Influenza Virus Research Studies
- COVID-19 epidemiological studies
- Quantum and electron transport phenomena
- SARS-CoV-2 and COVID-19 Research
- Graphene research and applications
- Animal Disease Management and Epidemiology
- Data-Driven Disease Surveillance
- Topological Materials and Phenomena
- vaccines and immunoinformatics approaches
- Quantum many-body systems
- Receptor Mechanisms and Signaling
- Immune Response and Inflammation
- Estrogen and related hormone effects
- Immunotherapy and Immune Responses
- Advanced Thermodynamics and Statistical Mechanics
- Biometric Identification and Security
- Blood donation and transfusion practices
- Cancer, Lipids, and Metabolism
- Animal Virus Infections Studies
- Neural Networks and Reservoir Computing
- Menopause: Health Impacts and Treatments
- Quantum Mechanics and Non-Hermitian Physics
- Poxvirus research and outbreaks
Sun Yat-sen University
2020-2024
Beijing Academy of Quantum Information Sciences
2023-2024
Shenzhen Blood Center
2023
University of Hong Kong
2021
Hong Kong University of Science and Technology
2021
Institute of Physics
2019
University of Chinese Academy of Sciences
2019
National Laboratory for Superconductivity
2019
Chinese Academy of Sciences
2019
Yanshan University
2017
Quantum mechanics is inherently probabilistic in light of Born's rule. Using quantum circuits as generative models for classical data exploits their superior expressibility and efficient direct sampling ability. However, training can be more challenging compared to neural networks due the lack an differentiable learning algorithm. We devise adversarial quantum-classical hybrid scheme via coupling a circuit generator network discriminator together. After training, model infer missing with...
A range of strict nonpharmaceutical interventions (NPIs) were implemented in many countries to combat the coronavirus 2019 (COVID-19) pandemic. These NPIs may also be effective at controlling seasonal influenza virus infections, as viruses have same transmission path severe acute respiratory syndrome 2. The aim this study was evaluate effects different on control influenza.Data for 14 33 and corresponding virological surveillance data collected. suppression index calculated difference...
Head and neck squamous cell carcinomas (HNSCCs) are a type of cancer originating in the mucosal epithelium mouth, pharynx, larynx, sixth most common world. However, there is no effective treatment for HNSCCs. More than 90% HNSCCs overexpress epidermal growth factor receptors (EGFRs). Although small molecule inhibitors monoclonal antibodies have been developed to target EGFRs, few EGFR-targeted therapeutics approved clinical use. Ferroptosis new kind programmed death induced by iron catalyzed...
We study the vortex bound states in three dimensional (3D) superconducting Dirac semimetals with time reversal symmetry. Assuming two points on kz-axis and bulk s-wave superconductivity, a quantum line parallel to z-direction, we find that has robust quasi-1D nodal phase. The phase stems from symmetry protected normal state bands, it can be characterized by topological index (\nu; n) at kz = 0 \pi, where \nu is Z2 invariant for 0D class-D system n Z class-A according Altland- Zirnbauer...
Abstract SpinQ Gemini is a commercial desktop quantum computing platform designed and manufactured by Technology. It an integrated hardware-software system. The first generation product with two qubits was launched in January 2020. hardware based on NMR spectrometer, permanent magnets providing ∼1 T magnetic field. operates under room temperature (0–30°C), highlighting its lightweight (55 kg volume of $70\times 40 \times 80\text{ cm}^{3}$ <mml:math...
Coronavirus disease 2019 is an infectious caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Influential variants and mutants of this virus continue to emerge, more effective virus-related information urgently required for identifying predicting new mutants. According earlier reports, synonymous substitutions were considered phenotypically silent; thus, such mutations frequently ignored in studies viral because they did not directly cause amino acid changes. However,...
With the rapid global spread of Coronavirus Disease 2019 (COVID-19) pandemic, a safe and effective vaccine against human coronaviruses (HCoVs) is believed to be top priority in field public health. Due frequent outbreaks different HCoVs, development pan-HCoVs great value biomedical science. The antigen design key prerequisite for efficacy, we therefore developed novel with broad coverage based on genetic algorithm mosaic strategy. designed has potentially conserved cytotoxic T lymphocyte...
Hamiltonian diagonalization is at the heart of understanding physical properties and practical applications quantum systems. It highly desired to design algorithms that can speedup diagonalization, especially those be implemented on near-term devices. In this work, we propose a variational algorithm for Hamiltonians (VQHD) systems, which explores important properties, such as temperature, locality correlation, system. The key idea thermal states system encode information eigenvalues...
Circulation of seasonal influenza is the product complex interplay among multiple drivers, yet characterizing underlying mechanism remains challenging. Leveraging diverse seasonality A(H3N2) virus and abundant climatic space across regions in China, we quantitatively investigated relative importance population susceptibility, factors, antigenic change on dynamics through an integrative modelling framework. Specifically, absolute humidity driven multiscale transmission model was constructed...
Deep learning for face identification-verification application has been proven to be fruitful. Human faces constituted the main information human identification besides gait, body silhouette, etc. forensic could provide quantitative indexes similarity measurement between questioned and known in cases, which had advantage of result objectivity without expert experience influences. We studied deep based representation verification images. Its strategies technical limitations were discussed....
New HIV (Human immune deficiency virus) infections are continuously increasing in China and it remains a huge challenge to blood donation. As access health services has affected by COVID-19 (Corona virus disease 2019) pandemic, drop new diagnoses (especially HIV) was observed worldwide.During 2013-2021, 735,247 specimens from unpaid donors collected Shenzhen Blood Center underwent ELISA (Enzyme -linked immunosorbent assay) NAT (Nucleic acid test). Samples with reactivity results were sent...
With the rapid advancement of quantum computing, hybrid quantum–classical machine learning has shown numerous potential applications at current stage, with expectations being achievable in noisy intermediate-scale (NISQ) era. Quantum reinforcement learning, as an indispensable study, recently demonstrated its ability to solve standard benchmark environments formally provable theoretical advantages over classical counterparts. However, despite progress processors and emergence computing...
Abstract The 2019 novel coronavirus (SARS-CoV-2) has spread rapidly worldwide and was declared a pandemic by the WHO in March 2020. evolution of SARS-CoV-2, either its natural reservoir or human population, is still unclear, but this knowledge essential for effective prevention control. We propose new framework to systematically identify recombination events, excluding those due noise convergent evolution. found that several events occurred SARS-CoV-2 before transfer humans, including more...
Characterizing the spatial transmission pattern is critical for better surveillance and control of human influenza. Here, we propose a mutation network framework that utilizes theory to study influenza H3N2. On basis network, analysis captured circulation from global simulation Furthermore, this method was applied explore, in detail, patterns within Europe, United States, China, revealing regional spread The proposed here could facilitate understanding, surveillance, other infectious diseases.
The immune system is highly networked and complex, which continuously changing as encountering old new pathogens. However, reductionism-based researches do not give a systematic understanding of the molecular mechanism response viral pathogenesis. Here, we present HUMPPI-2022, high-quality human protein-protein interaction (PPI) network, containing &gt; 11,000 protein-coding genes with 78,000 interactions. network topology functional characteristics analyses immune-related (IRGs) reveal...
SpinQ Gemini is a commercial desktop quantum computer designed and manufactured by Technology. It an integrated hardware-software system. The first generation product with two qubits was launched in January 2020. hardware based on NMR spectrometer, permanent magnets providing $\sim 1$ T magnetic field. operates under room temperature ($0$-$30^{\circ}$C), highlighting its lightweight (55 kg volume of $70\times 40 \times 80$ cm$^3$), cost-effective (under $50$k USD), maintenance-free. aims to...
Abstract Inferring a quantum system from incomplete information is common problem in many aspects of science and applications, where the principle maximum entropy (MaxEnt) plays an important role. The state compatibility asks whether there exists density matrix compatible with some given measurement results. Such can be naturally formulated as semidefinite programming (SDP), which searches directly for existence . However, large dimensions, it hard to represent directly, since requires too...
Introduction Influenza susceptibility difference is a widely existing trait that has great practical significance for the accurate prevention and control of influenza. Methods Here, we focused on human to seasonal influenza A/H3N2 healthy adults at baseline level. Whole blood expression data from GEO were collected firstly (30 symptomatic 19 asymptomatic). Then explore differences baseline, suite systems biology approaches - differential analysis, co-expression network immune cell...
Variational quantum eigensolver (VQE) is promising to show advantage on near-term noisy-intermediate-scale (NISQ) computers. One central problem of VQE the effect noise, especially physical noise realistic We study systematically for algorithm, by performing numerical simulations with various local models, including amplitude damping, dephasing, and depolarizing noise. that ground state energy will deviate from exact value as probability increase normally accumulate circuit depth increase....
Abstract Background: A range of strict nonpharmaceutical interventions (NPIs) had been implemented in many countries to combat the COVID-19 pandemic. These NPIs might also be effective controlling seasonal influenza virus, which share same transmission path with SARS-CoV-2. The aim this study is evaluate effect different for control influenza. Methods: Data on 14 33 and corresponding data virologic surveillance were collected. suppression index was calculated as difference between...
The anomalous non-Hermitian dynamical phenomenon with the skin effect (NHSE) attracts wide attention due to its novel physics and promising applications. Here, we propose a new type of non-unitary discrete-time quantum walk system demonstrating NHSE phenomena, including chiral phenomenon, funneling on domain wall, reflection phase impurity. Furthermore, design circuit experiments these systems numerically simulate them noises verify robustness noisy intermediate-scale (NISQ) devices. Our...