A5100458222- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Cell Adhesion Molecules Research
- COVID-19 and Mental Health
- Asthma and respiratory diseases
- Viral Infections and Immunology Research
- Food Allergy and Anaphylaxis Research
- Intraperitoneal and Appendiceal Malignancies
- Pituitary Gland Disorders and Treatments
- Monoclonal and Polyclonal Antibodies Research
- Pelvic floor disorders treatments
- Urinary Bladder and Prostate Research
- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Platelet Disorders and Treatments
- Appendicitis Diagnosis and Management
- Allergic Rhinitis and Sensitization
- Evolution and Genetic Dynamics
- Facial Rejuvenation and Surgery Techniques
- Meta-analysis and systematic reviews
- Geographic Information Systems Studies
- Child and Adolescent Psychosocial and Emotional Development
- Time Series Analysis and Forecasting
- Abdominal Trauma and Injuries
- SARS-CoV-2 detection and testing
University of Oslo
2018-2025
Guangxi Medical University
2024
Norwegian Institute of Public Health
2022-2024
Zhejiang Gongshang University
2023
Sichuan University
2020-2023
Sun Yat-sen University
2021-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2017-2023
Affiliated Hospital of Southwest Medical University
2022-2023
Advanced Medical Research Institute
2023
Qilu Hospital of Shandong University
2023
There are four human coronaviruses (HCoVs), distributed worldwide, that associated with a range of respiratory symptoms. The discovery severe acute syndrome (SARS)-CoV and Middle East (MERS)-CoV shows HCoVs pose significant threat to health. Our work aims develop sensitive method (mCoV-MS) which can not only identify known accurately, but also have the ability provide clues for emerging HCoVs. was performed using MassARRAY matrix-assisted laser desorption/ionization time-of-flight mass...
Abstract Background Improved quality of life (QoL) after oral immunotherapy (OIT) in peanut allergic children is often reported by their parents, while the child's perspective less clear. Objective We aimed to explore whether 2 years OIT improved QoL with allergy and identify factors influencing change QoL. Methods In open‐labeled TAKE‐AWAY trial including anaphylaxis peanuts, 57 were randomized 20 observation. The Pediatric Quality Life Inventory Version 4.0 was completed parents at...
Human coronaviruses (HCoVs) HCoV-NL63, HCoV-229E, HCoV-HKU1 and HCoV-OC43 have been circulated in the human population worldwide, they are associated with a broad range of respiratory diseases varying severity. However, there neither effective therapeutic drugs nor licensed vaccines available for treatment prevention infections by four HCoVs. In this study, we collected nasopharyngeal aspirates children hospitalized tract infection China during 2014-2018 conducted next-generation sequencing....
Objectives We aimed to estimate the prevalence of chronic bronchitis (CB), examine its association with occupational exposure irritants assessed by self-reporting or Nordic job matrix (N-JEM) stratified smoking status and population-attributable fraction (PAF) CB from exposure. Methods A two-phased, cross-sectional design was used analyse a random sample collected in 2013 2018 population aged 16–55 years Telemark County, Norway. defined as cough sputum production for ≥3 months over 2...
Background: Traumatic spinal injury (TSI) is associated with significant fatality and social burden; however, the epidemiology treatment of patients TSI in US remain unclear. Materials methods: An adult population was selected from National Inpatient Sample database 2016 to 2019. incidence calculated TSI-related hospitalizations were divided into operative nonoperative groups according treatments received. TSIs classified as fracture, dislocation, internal organ injury, nerve root or sprain...
The aim was to estimate the prevalence of harmful alcohol use in relation socio-demographic characteristics among acutely ill medical patients, and examine identification measures use, including biomarker phosphatidylethanol 16:0/18:1 (PEth).A cross-sectional study, lasting one year at hospital Oslo, Norway Moscow, Russia recruiting acute medically patients (≥ 18 years), able give informed consent. Self-reported data on socio-demographics, mental distress (Symptom Check List-5), (Alcohol Use...
Coronavirus disease 2019 is an infectious caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Influential variants and mutants of this virus continue to emerge, more effective virus-related information urgently required for identifying predicting new mutants. According earlier reports, synonymous substitutions were considered phenotypically silent; thus, such mutations frequently ignored in studies viral because they did not directly cause amino acid changes. However,...
Describe patient transfer patterns within a large Norwegian hospital. Identify risk factors associated with high number of transfers. Develop methods to monitor intrahospital flows support capacity management and infection control. Retrospective observational study linked clinical data from electronic health records. Tertiary care university hospital in the Greater Oslo Region, Norway. All adult (≥18 years old) admissions gastroenterology, gastrointestinal surgery, neurology orthopaedics...
To assess total antibody levels against Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS CoV-2) spike protein up to 12 months after Coronavirus Disease (COVID-19) infection in non-vaccinated individuals and the possible predictors of persistence.This is first part a prospective multi-centre cohort study.The study included SARS-CoV-2 real-time polymerase chain reaction (RT-PCR) positive negative participants South-Eastern Norway from February December 2020. Possible persistence was...
Background: Our previous studies showed that tetraspanin CD151 was implicated in the progression of hepatocellular carcinoma (HCC), mainly depending on formation functional complexes with molecular partners, including Mortalin. In this study, we investigate role mortalin CD151-depedent HCCs. Methods: Immunofluorescent staining, western blot and quantitative real-time polymerase chain reaction (qRT-PCR) were used to expression location Mortalin four HCC cell lines different metastatic...
Coronavirus disease 2019, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), poses a considerable threat to global public health. This study developed and evaluated rapid, low-cost, expandable, sequencing-free high-resolution melting (HRM) assay for direct detection of SARS-CoV-2 variants. A panel 64 common bacterial viral pathogens that can cause tract infections was employed evaluate our method's specificity. Serial dilutions isolates determined sensitivity method....
Abstract The 2019 novel coronavirus (SARS-CoV-2) has spread rapidly worldwide and was declared a pandemic by the WHO in March 2020. evolution of SARS-CoV-2, either its natural reservoir or human population, is still unclear, but this knowledge essential for effective prevention control. We propose new framework to systematically identify recombination events, excluding those due noise convergent evolution. found that several events occurred SARS-CoV-2 before transfer humans, including more...
EDSM, an endostatin-derived synthetic polypeptide, contains the amino acids 6-48 of endostatin from its N-terminus, which could inhibit human umbilical vein endothelial cell (HUVEC) migration and tumor growth. To increase targeted delivery EDSM to tumors further enhance antiangiogenic activity, RGD sequence (Arg-Gly-Asp) was introduced into two peptides were obtained: EDSM-X with on N-terminus EDSM-Y C-terminus. Both modified showed a significant activity in HUVEC assay, tube formation...
Surgery is the primary treatment of choice for all symptomatic pituitary adenomas except prolactinomas. Common postoperative complications include endocrinopathies, vision impairment and cerebrospinal fluid leak. The present study assessed 153 continuous microscopic surgeries performed by an author between 2010 to 2014. Patients underwent either transphenoidal or transcranial surgery depending on their individual tumor characteristics. Five typical cases are presented in intraoperative...
This study aims to assess risk factors for SARS-CoV-2 infection by combined design; first comparing positive cases negative controls as determined PCR testing and then these two groups an additional prepandemic population control group.