A5029081388- Extracellular vesicles in disease
- MicroRNA in disease regulation
- Tissue Engineering and Regenerative Medicine
- Circular RNAs in diseases
- Electrospun Nanofibers in Biomedical Applications
- Inflammatory Biomarkers in Disease Prognosis
- Infectious Aortic and Vascular Conditions
Universidade Nova de Lisboa
2023-2024
Instituto de Biologia Experimental e Tecnológica
2023-2024
The short shelf life of platelet concentrates (PC) up to 5-7 days leads higher wastage due expiry. To address this massive financial burden on the healthcare system, alternative applications for expired PC have emerged in recent years. Engineered nanocarriers functionalized with membranes shown excellent targeting abilities tumor cells owing their membrane proteins. Nevertheless, synthetic drug delivery strategies significant drawbacks that platelet-derived extracellular vesicles (pEV) can...
Abstract The “QuantitatEVs: multiscale analyses, from bulk to single vesicle” workshop aimed discuss quantitative strategies and harmonized wet computational approaches toward the comprehensive analysis of extracellular vesicles (EVs) vesicle analyses with a special focus on emerging technologies. covered key issues in different EV‐associated molecular components EV biophysical features, which are considered core biomarker discovery validation for their clinical translation. in‐person‐only...
Extracellular vesicle (EV)-based approaches for promoting angiogenesis have shown promising results. Yet, further development is needed in vehicles that prolong EV exposure to target organs. Here, we hypothesized microfiber-reinforced gelatin methacryloyl (GelMA) hydrogels could serve as sustained delivery platforms human induced pluripotent stem cell (hiPSC)-derived EV. with 50-200 nm size and typical morphology were isolated from hiPSC-conditioned culture media tested negative common...