A5087920669- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Nerve injury and regeneration
- Angiogenesis and VEGF in Cancer
- Parkinson's Disease Mechanisms and Treatments
- Neurological Disease Mechanisms and Treatments
- Neurogenesis and neuroplasticity mechanisms
- Orthopedic Surgery and Rehabilitation
- MicroRNA in disease regulation
- Mitochondrial Function and Pathology
- Alzheimer's disease research and treatments
- Connective tissue disorders research
- Urinary Bladder and Prostate Research
- Neuroscience of respiration and sleep
- Genetics and Neurodevelopmental Disorders
- Aortic Disease and Treatment Approaches
- Osteoarthritis Treatment and Mechanisms
- Circular RNAs in diseases
- Mesenchymal stem cell research
- Vagus Nerve Stimulation Research
- Peptidase Inhibition and Analysis
- NF-κB Signaling Pathways
- Neuroscience and Neuropharmacology Research
- Bone Tissue Engineering Materials
- Crop Yield and Soil Fertility
Army Medical University
2008-2023
Southwest Hospital
2023
Hunan Agricultural University
2023
Chongqing University
2016
Nanchang University
2014
MicroRNA-206 (miR-206) is known to regulate cell proliferation and migration involved in various types of cancer. However, the role miR-206 human hepatocellular carcinoma (HHC) has not been previously reported. In present study, expression Notch3 HCC adjacent non-neoplastic tissue was immunohistochemically assessed on formalin-fixed, paraffin-embedded sections. mimics were transiently transfected into HepG2 cells using Lipofectamine™ 2000. Subsequently, we evaluated proliferation, apoptosis,...
Rice yields can only be achieved by selecting a high-quality population. Nitrogen rates and transplanting density play significant role in determining population quality yield. Field experiments were conducted Heshan District, Hunan Province, China, to explore suitable nitrogen appropriate densities for rice production 2021 2022. In this study, three levels of nitrogen, e.g., N1, N2, N3 (0, 150, 210) kg ha−1, densities, B1, B2, B3 (1, 2, 3) seedlings per hill used study their individual or...
Synthetic small-diameter vascular grafts are of limited use mainly due to the lack endothelial cells (ECs), which inhibit intraluminal thrombosis and intimal hyperplasia. Grafts loaded with homing factors for circulating progenitor (EPCs) have potential achieve in situ endothelialization. In view important role that EPCs play construction artificial blood vessels, antioxidant therapy aiming oxidative stress-induced EPC apoptosis should be focus clinical interest. this study, polyethylene...
A tissue-engineered blood vessel (TEBV) modified with CS/β-CD nanoparticles is constructed, effectively controling the release of adenosine, and this type TEBV can keep open for over 6 months. This study also demonstrates first time that adenosine promotes endothelial progenitor cell (EPC) mobilization homing via energy conversion, achieving rapid endothelialization TEBV. As a service to our authors readers, journal provides supporting information supplied by authors. Such materials are peer...
Recent studies from environmental toxicology and molecular genetics demonstrate that midbrain dopamine (DA) neurons are particularly vulnerable to microtubule depolymerizing agents, indicating the involvement of dysfunction in pathogenesis Parkinson's disease. Here we show intrastriatal injection colchicine (COL), a well-known disruptor, induced degeneration striatonigral pathway. Microtubule disruption caused by unilateral COL blocked retrograde axonal transport fluorogold previously...
Properties of the cell-material interface are determining factors in successful function cells for cartilage tissue engineering. Currently, cell adhesion is commonly promoted through use polypeptides; however, due to their lack complementary or modulatory domains, polypeptides must be modified improve ability promote adhesion. In this study, we utilized principle matrix-based biomimetic modification and a recombinant protein, which spans fragments 7–10 fibronectin module III (heterophilic...
Small-diameter tissue-engineered blood vessels (TEBVs) have been associated with low, long-term patency rates primarily because of acute thrombosis in early stages and an inability to achieve endothelialization. Platelets endothelial progenitor cells (EPCs) play a key role these processes. A nano delayed-release 5-aminoimidazole-4-carboxamide 1-β-D-ribofuranoside (AICAR)-bound TEBV was implanted rat carotid arteries for 3 months. AICAR-bound TEBVs had high rate compared control after We...
To determine if A20, a zinc finger protein that mediates the inflammatory response, affects monocyte-endothelial cell-cell interactions induced by low shear flow.Primary cultured endothelial cells (EC) were transfected with an A20 expression vector, and VCAM-1, ICAM-1 IL-8 mRNA, levels in A20-transfected EC lysates checked PCR array ELISA, respectively. CD14-positive monocyte migration toward adhesion to measured using parallel plate flow chamber.Low stress, defined as 0.2 Pa for 6 h,...
When tying knots, some surgeons do not pay particular attention to the direction in which they pull lay down throws. We examine what extent does pulling influence on knot security.