H Wu

ORCID: 0000-0002-8335-7712
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About
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Research Areas
  • Wheat and Barley Genetics and Pathology
  • Genetics and Plant Breeding
  • Genetic Mapping and Diversity in Plants and Animals
  • Nanoplatforms for cancer theranostics
  • Plant nutrient uptake and metabolism
  • Seaweed-derived Bioactive Compounds
  • Functional Brain Connectivity Studies
  • Power Systems and Renewable Energy
  • Advanced Neuroimaging Techniques and Applications
  • Circular RNAs in diseases
  • Prenatal Screening and Diagnostics
  • Power Systems and Technologies
  • Date Palm Research Studies
  • Minimally Invasive Surgical Techniques
  • Endoplasmic Reticulum Stress and Disease
  • Catalysis for Biomass Conversion
  • Abdominal Surgery and Complications
  • Smart Grid and Power Systems
  • MicroRNA in disease regulation
  • Asymmetric Hydrogenation and Catalysis
  • Ureteral procedures and complications
  • Peroxisome Proliferator-Activated Receptors
  • Polysaccharides and Plant Cell Walls
  • Microbial Metabolites in Food Biotechnology
  • Ubiquitin and proteasome pathways

Zhejiang Chinese Medical University
2025

South China University of Technology
2025

University of Science and Technology of China
2024

Guangzhou Institute of Energy Conversion
2024

Chinese Academy of Sciences
1996-2024

Institute of Botany
2023

University of Chinese Academy of Sciences
2023

Qingdao Women and Children's Hospital
2022-2023

Yunnan Agricultural University
2023

Qingdao University
2022-2023

Abstract Hepatocellular carcinoma (HCC) is one of the leading cause cancer death in world. Fructose-1,6-biphosphatase (FBP1), a rate-limiting enzyme gluconeogenesis, has been identified recently as tumor suppressor HCC and other types. In this study, we demonstrated that tripartite motif-containing protein 28 (TRIM28) binds directly to promotes FBP1 for ubiquitination degradation. MAGE-A3 MAGE-C2, which are known be overexpressed HCC, can enhance TRIM28-dependent degradation by forming...

10.1038/oncsis.2017.21 article EN cc-by Oncogenesis 2017-04-10

Abstract Background Plant architecture associated with increased grain yield and adaptation to the local environments is selected during wheat ( Triticum aestivum ) breeding. The internode length of individual stems tiller plants are important for determination plant architecture. However, few studies have explored genetic basis these traits. Results Here, we conduct a genome-wide association study (GWAS) dissect geographical differentiation traits in 306 worldwide accessions including both...

10.1186/s13059-023-02932-x article EN cc-by Genome biology 2023-05-12

Previous studies have shown that echinocystic acid (EA) can reduce arthritis and skin damage, but the role of EA in psoriatic is unclear. This study aims to prove arthritis, which was induced by intraperitoneal injection mannan C57BL/6J mice. The mice were divided into a control group, + (low-dose) (high dose) group. Joint tissue damage scored, pathological changes joint ear examined HE staining. Pathway enrichment drug targets performed through target website, mRNA protein expression levels...

10.15586/aei.v53i2.1283 article EN Allergologia et Immunopathologia 2025-03-01

Abstract SARS-CoV-2 can encode circular RNAs (circRNAs); however, the potential effects of exogenous circRNAs on cardiovascular sequelae remain unknown. Three derived from nucleocapsid (N) gene SARS-CoV-2, namely, circSARS-CV2-Ns, were identified for functional studies. In particular, circSARS-CV2-N1368 was shown to enhance platelet adhesiveness endothelial cells (ECs) and inhibit EC-dependent vascular relaxation. Moreover, expression suppressed EC proliferation migration decreased...

10.1038/s41401-025-01516-8 article EN cc-by Acta Pharmacologica Sinica 2025-03-11

Some haplotypes of the sucrose synthase gene TaSus1 are associated with thousand-grain weight (TGW) in wheat (Triticum aestivum L.). However, no mutations have been identified within to test this association. The effects on grain number per spike (GNS) also largely unknown. Our previous genome-wide association study TaSus-A1 as a candidate controlling fertile spikelet (FSN). In present study, we generated two independent mutants for three homoeologs by CRISPR/Cas9-mediated genome editing....

10.1016/j.cj.2023.11.007 article EN cc-by-nc-nd The Crop Journal 2023-12-17

Palm kernel cake is a very important agro-industrial by-product from the production of palm oil.It contains lot nutrients needed by chicken for growth and productivity but this potential hindered because presence mannan other anti-nutritional factors.Mannans are made up simple sugar D-mannose.Mannans comprise linear backbone mannose residues joined β-1, 4-mannosidic linkages comprising glucomannan, galactomannan galactoglucomannan depending on carbohydrates or acid substitutions in...

10.36899/japs.2020.3.0061 article EN cc-by-nc The Journal of Animal and Plant Sciences 2020-03-25

耳蜗血管纹中的血-迷路屏障(blood-labyrinth barrier,BLB)是一种特殊分化的毛细血管网,可控制物质从毛细血管进入内淋巴。本文详述了BLB的组织学结构、维持内淋巴成分稳定的机制,及其在部分感音神经性聋发病机制中的作用,概述了BLB在内耳药物递送研究方面的进展,以期为感音神经性聋的发病机制与防治提供新的思路。.

10.3760/cma.j.cn115330-20210710-00448 article EN PubMed 2022-06-07

过敏反应和过敏性疾病与分泌性中耳炎(otitis media with effusion,OME)的发生密切相关。OME患者的中耳黏膜和中耳积液中存在过敏反应相关的细胞及炎性介质,抗过敏治疗也已被证实可使部分OME患者获益。但OME本身是否是一种过敏性疾病目前仍有较大争议。本文详细阐述了过敏反应在OME发病机制中的作用,概述了抗过敏及免疫治疗在OME治疗中的现状和前景,以期能够为OME的发病机制及防治提供新的认识。.

10.3760/cma.j.cn115330-20210611-00346 article ZH-CN PubMed 2022-08-07

Abstract Background Prader-Willi syndrome (PWS) is a genetic disorder involving multiple systems, with an incidence of about 1/10000–25000. Ovarian torsion (OT) not commonly found in children. cyst acts as one the primary factors resulting OT. While ovarian Syndrome has been reported before. Case presentation A 12-years old female was admitted to Emergency Department our hospital chief complaint abdominal pain. The outcomes physical examination revealed height 150 cm, weight 103 kg, BMI...

10.1186/s12887-023-04223-7 article EN cc-by BMC Pediatrics 2023-08-08

In the present study, we report a retrospective analysis of 23 cases conjunctival congestion after laparoscopic operation in children and try to explore causes intervention measures.This is retrospective, single-centre observational all patients with admitted our institution between August 2021 December were included this study. Records including 16 male 7 female retrospectively analysed. These age group 2-12 years. Their primary symptom was different degrees congestion, onset 2 days...

10.4103/jmas.jmas_97_22 article EN cc-by-nc-sa Journal of Minimal Access Surgery 2022-07-06
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