Muhammad Siyab Panhwar

ORCID: 0000-0002-8338-7524
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About
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Research Areas
  • Cardiac Valve Diseases and Treatments
  • Mechanical Circulatory Support Devices
  • Transplantation: Methods and Outcomes
  • Cardiovascular Function and Risk Factors
  • Renal Transplantation Outcomes and Treatments
  • Cardiac Structural Anomalies and Repair
  • Infective Endocarditis Diagnosis and Management
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac Arrest and Resuscitation
  • Heart Failure Treatment and Management
  • Venous Thromboembolism Diagnosis and Management
  • Hospital Admissions and Outcomes
  • Influenza Virus Research Studies
  • Gastroesophageal reflux and treatments
  • Healthcare Operations and Scheduling Optimization
  • Organ Transplantation Techniques and Outcomes
  • Healthcare Policy and Management
  • Emergency and Acute Care Studies
  • Inflammatory Bowel Disease
  • Microscopic Colitis
  • Appendicitis Diagnosis and Management
  • Aortic Disease and Treatment Approaches
  • Neuroendocrine Tumor Research Advances
  • Pneumocystis jirovecii pneumonia detection and treatment

New York University
2023

Tulane University
2019-2022

University Medical Center
2022

University Hospital and Clinics
2022

University Hospitals of Cleveland
2017-2020

Case Western Reserve University
2017-2020

Southeast Louisiana Veterans Health Care System
2020

University Medical Center New Orleans
2020

University School
2019

Weill Cornell Medical College in Qatar
2014-2015

Chronic inflammation is linked to increased cardiovascular risk. Inflammatory bowel disease (IBD) characterized by chronic of the gastrointestinal tract and elevated pro-inflammatory markers. The association between IBD myocardial infarction (MI) not well understood. We sought elucidate this risk using a large database.We reviewed data from commercial database (Explorys, IBM Watson) that aggregates electronic medical records 26 nationwide health care systems. Using systemized nomenclature...

10.1093/ibd/izy354 article EN Inflammatory Bowel Diseases 2018-11-30

Glucose-dependent insulinotropic polypeptide (GIP), an incretin hormone secreted from gastrointestinal K cells in response to food intake, has important role the control of whole-body metabolism.GIP signals through activation GIP receptor (GIPR), a G-protein-coupled (GPCR).Dysregulation this pathway been implicated development metabolic disease.Here we demonstrate that GIPR is constitutively trafficked between plasma membrane and intracellular compartments both GIP-stimulated unstimulated...

10.1128/mcb.00256-14 article EN Molecular and Cellular Biology 2014-07-22

Abstract Objectives To understand the prevalence of malnutrition and its association with chronic limb‐threatening ischemia (CLTI) outcomes; to clarify differential impact revascularization methods on assess ability CLTI Frailty Risk Score (CLTI‐FRS) predict adverse events in patients hospitalized CLTI. Background Despite advances management CLTI, a majority still undergo major amputation, minority heal within 6 months. There is lack validated assessment tools for identification frailty...

10.1002/ccd.30113 article EN Catheterization and Cardiovascular Interventions 2022-02-03

R eports from countries struck by the coronavi- rus disease-2019 (COVID-19) pandemic have consistently highlighted physician shortages and utilization of physicians not specifically trained in critical care to for patients with COVID-19.Given significant overlap between cardiology care, cardiologists may be among first asked step fill this shortage.If when occurs, a basic framework recognition acute respiratory failure, distress syndrome (ARDS), initial ventilator management is...

10.1016/j.jaccas.2020.03.007 article EN cc-by-nc-nd JACC Case Reports 2020-03-27

Abstract Importance The impact of pre‐existing cognitive dysfunction on outcomes after transcatheter aortic valve replacement (TAVR) remains unclear. Objective To study the association between dementia and post‐TAVR outcomes. Design Cohort with propensity‐score matching was conducted using Nationwide Inpatient Sample. Exposures History at time undergoing TAVR. Main All‐cause in‐hospital mortality, stroke, bleeding requiring transfusion, acute kidney injury, post‐procedural vascular...

10.1111/jgs.17048 article EN Journal of the American Geriatrics Society 2021-02-11

Crohn's disease (CD) and ulcerative colitis (UC) involve an inflammatory state where sleep dysregulation is common. Little known about implications, if any, of bowel (IBD) on the development obstructive apnea (OSA). This study aims to investigate IBD patients are at higher risk for OSA.This retrospective multivariate analysis utilized a commercial database named Explorys (IBM Watson). We identified from 1/2015 1/2020 with UC CD. Cohorts these without OSA were then created prevalence values...

10.1093/crocol/otac026 article EN cc-by Crohn s & Colitis 360 2022-07-01

Tolosa-Hunt syndrome, an idiopathic granulomatous inflammation of the cavernous sinus, is primarily a diagnosis exclusion. The majority patients present with unilateral orbital pain and features suggestive paralysis one or more cranial nerves passing through sinus and/or superior fissure. MRI head may show enhancement apex. Treatment high-dose intravenous steroids followed by tapering oral steroids. Rapid amelioration within 24–48 h supports this rare diagnosis. Resolution neuropathies take...

10.1136/bcr-2015-210646 article EN BMJ Case Reports 2015-08-20

10.1016/j.jacc.2020.05.010 article EN publisher-specific-oa Journal of the American College of Cardiology 2020-06-01

Objectives Studies on the incidence of venous thromboembolism (VTE) in acute pancreatitis (AP) are scarce. We conducted a large database study to evaluate this relationship. Methods Data were extracted from electronic health record (Explorys; IBM Watson Health, Armonk, NY). identified patients with AP 2018 and 2019, analyzing VTE at 30 days after diagnosis AP. Univariate multivariate analyses performed identify risk factors associated VTE. Results A total 25,620 cases necrotizing (ANP)...

10.1097/mpa.0000000000001714 article EN Pancreas 2020-12-16

Background While venous thromboembolism (VTE) prophylaxis is a strong recommendation after most surgeries, it controversial in cardiac surgeries such as coronary artery bypass grafting (CABG), because of perceived low VTE incidence and increased bleeding risk. Prior studies may not have been adequately powered to study outcomes this population. We sought investigate the postoperative CABG patients using large national inpatient database. Methods Results utilized 2013 2014 National Inpatient...

10.1161/jaha.119.013246 article EN cc-by-nc-nd Journal of the American Heart Association 2019-09-19

The incidence of acute diverticulitis is increasing, and previous studies showed a wide range prevalence colorectal cancer after diverticulitis. There lack high-quality evidence to support performing colonoscopy diverticulitis.We aimed describe the first-ever postdiverticulitis in United States.This retrospective cohort study.We queried national database that contains data from 26 major integrated healthcare systems States.We identified an aggregated patient aged ≥18 years with diagnosis...

10.1097/dcr.0000000000001837 article EN Diseases of the Colon & Rectum 2020-08-10

10.1093/eurheartj/ehz264 article EN European Heart Journal 2019-05-14

BackgroundWe aimed to study the use patterns of short-term mechanical circulatory support (MCS) for cardiogenic shock and associated in-hospital outcomes.MethodsWe queried National Inpatient Sample from 2012 2015 identify patients with a diagnosis CS, stratified by presence acute myocardial infarction (AMI-CS or non-AMI-CS). We then studied trends in MCS. Our primary outcome was mortality.ResultsOf 422,575 patients, 44.7% had AMI-CS. From 2015, we observed decrease overall MCS (23.9% 20.5%,...

10.1080/24748706.2019.1669234 article EN cc-by-nc-nd Structural Heart 2019-09-27

Data on next-day discharge (NDD) after transcatheter aortic valve replacement (TAVR) are limited. This study investigated the feasibility and safety of NDD as a first-line option (the very-early [VED] strategy) compared with early-discharge (ED) strategy (2-3 days option) TAVR. We reviewed 611 consecutive patients who had minimalist TAVR (transfemoral approach under conscious sedation) no in-hospital mortality; total 418 underwent ED (since December 2013) 193 VED (as part hospital initiative...

10.25270/jic/18.00300 article EN Deleted Journal 2019-03-01

Takotsubo cardiomyopathy (TCM), colloquially known as “broken heart syndrome,” is a relatively uncommon transient condition that characterized by left ventricular apical ballooning [1]. It purported to be triggered exorbitant physical or emotional stressors. The clinical picture elicited TCM closely mimics of acute coronary syndrome (ACS), with most patients presenting substernal chest pain and ECG changes akin those observed in patient myocardial infarction Interestingly, cases TCM,...

10.1016/j.amsu.2021.102291 article EN Annals of Medicine and Surgery 2021-04-16
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