A5068955137- Radiation Dose and Imaging
- Prostate Cancer Treatment and Research
- Radioactive element chemistry and processing
- Cancer, Lipids, and Metabolism
- Radioactive contamination and transfer
- Advanced Radiotherapy Techniques
- Cytokine Signaling Pathways and Interactions
- Phosphodiesterase function and regulation
- Ferroptosis and cancer prognosis
- Ethnobotanical and Medicinal Plants Studies
- Cancer-related Molecular Pathways
- Sexual function and dysfunction studies
- Nuclear reactor physics and engineering
- HER2/EGFR in Cancer Research
- Cancer, Hypoxia, and Metabolism
- Pancreatic and Hepatic Oncology Research
- Nuclear Materials and Properties
- Essential Oils and Antimicrobial Activity
- RNA Research and Splicing
- Radiation Therapy and Dosimetry
- Radioactivity and Radon Measurements
- Neuroendocrine Tumor Research Advances
- interferon and immune responses
- Bee Products Chemical Analysis
- Hedgehog Signaling Pathway Studies
University of Nebraska Medical Center
2020-2025
Bhabha Atomic Research Centre
2023-2024
Nebraska Medical Center
2023-2024
University of Dhaka
2018
Docetaxel plays an indispensable role in the management of advanced prostate cancer. However, more than half patients do not respond to docetaxel, and those good responders frequently experience significant cumulative toxicity, which limits its dose duration intensity. Hence, a second agent that could increase initial efficacy docetaxel maintain tolerability at biologically effective doses may improve outcomes for patients.We determined phosphodiesterase 5 (PDE5) expression levels human...
In routine monitoring of radiation workers to detect internal contamination due Pu/Am, it is assumed that intake has occurred at the midpoint interval. Radiation worker normally monitored end annual interval, within a span ±1 month under in vivo program. An uncertainty introduced estimation as time can vary over entire this work, uncertainties Type M and S compounds Pu/Am are evaluated unknown for biennial frequency.
The objective of the study was to evaluate antinociceptive and anthelmintic activities crude methanol extract leaves Leea aequata its fractions. fractions at 200- 400-mg/kg bw were subjected assay for their activity using acetic acid induced writhing radiant heat tail flicking methods. ethyl acetate soluble fraction 400 mg/kg 40.97% inhibition in mice while carbon tetrachloride chloroform same dose displayed with 40.28% as compared standard diclofenac sodium. elongated reaction time by...
Abstract The aberrant activation of the hedgehog (Hh) signaling pathway causes progression therapy-resistant castration-resistant prostate cancer (CRPC). In this study, we aimed to unravel biological significance Gli-family proteins and their functional involvement Gsk3β-mediated regulatory mechanism(s) in CRPC. We have discovered a novel function truncated form Gli (t-Gli3) advancing This was accomplished through silico analysis, vitro experiments, PCa patient clinical data, vivo MYC...
Chronic inhalation intake of radionuclides is possible for radiation workers in the nuclear industry. The International Commission on Radiological Protection (ICRP) provides organ retention fractions as well daily urinary and fecal excretion chronic various radionuclides. In this study, were estimated constant (CCI) realistic (RCI) scenarios. CCI a 1 Bq, RCI an 1.4 Bq five working days followed by two gap. Radiologically important such 239Pu, 60Co, 137Cs, 131I, 3H having long, moderate,...
Abstract Background: Docetaxel has been the most effective chemotherapeutic option after emergence of Castration-resistant prostate cancer (CRPC). However, more than 50% patients develop Resistance (DoceR) within three years treatment. It also shows severe adverse effects that lead to dose reduction and treatment failure. Thus, targeting underlying mechanism DoceR could improve survival benefits for CRPC patients. In this study, we identified leukemia inhibitory factor receptor (LIFR) as a...