Surinder K. Batra
A5085256777- Pancreatic and Hepatic Oncology Research
- Glycosylation and Glycoproteins Research
- Cancer Cells and Metastasis
- Helicobacter pylori-related gastroenterology studies
- Monoclonal and Polyclonal Antibodies Research
- Cancer Research and Treatments
- Cancer, Hypoxia, and Metabolism
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- Galectins and Cancer Biology
- Eosinophilic Esophagitis
- Pancreatic function and diabetes
- Cancer Genomics and Diagnostics
- Microtubule and mitosis dynamics
- Prostate Cancer Treatment and Research
- Lung Cancer Research Studies
- Cancer Immunotherapy and Biomarkers
- Caveolin-1 and cellular processes
- MicroRNA in disease regulation
- Ubiquitin and proteasome pathways
- Pancreatitis Pathology and Treatment
- IL-33, ST2, and ILC Pathways
- Peptidase Inhibition and Analysis
- HER2/EGFR in Cancer Research
- Angiogenesis and VEGF in Cancer
University of Nebraska Medical Center
2016-2025
Nebraska Medical Center
2015-2024
Indian Institute of Science Bangalore
2024
Universidad del Noreste
2024
Fred and Pamela Buffett Cancer Center
2013-2022
Susan Thompson Buffett Foundation
2013-2022
Iowa State University
2020-2022
City Of Hope National Medical Center
2022
Translational Genomics Research Institute
2021
The University of Texas MD Anderson Cancer Center
2015-2021
Conditional knockout mice and transgenic expressing recombinases, reporters, inducible transcriptional activators are key for many genetic studies comprise over 90% of mouse models created. generated using labor-intensive methods homologous recombination in embryonic stem cells available only ~25% all genes. Transgenic by random genomic insertion approaches pose problems unreliable expression, thus there is a need targeted-insertion models. Although CRISPR-based strategies were reported to...
A monospecific polyclonal antiserum against deglycosylated human pancreatic tumor mucin was used to select cDNA clones from a lambda gt11 expression library developed cell line. The full-length 4.4-kilobase sequence included 72-base pair 5‘-untranslated region and 307-base 3‘-untranslated region. predicted amino acid for this revealed protein of 122,071 daltons containing 1,255 residues which greater than 60% were serine, threonine, proline, alanine, glycine. Approximately two-thirds the...
Accumulating lines of experimental evidence have revealed that hypoxia-inducible factors, HIF-1α and HIF-2α, are key regulators the adaptation cancer- metastasis-initiating cells their differentiated progenies to oxygen nutrient deprivation during cancer progression under normoxic hypoxic conditions. Particularly, sustained stimulation epidermal growth factor receptor (EGFR), insulin-like factor-1 (IGF-1R), stem cell (SCF) KIT, transforming factor-β receptors (TGF-βRs) Notch downstream...
Pancreatic cancer (PC) is one of the most lethal malignancies. It has a 5-year survival rate only 6%, owing in part to lack reliable tumor marker for early diagnosis. Recent research shown that mucin protein MUC4 aberrantly expressed pancreatic adenocarcinoma cell lines and tissues but undetectable normal pancreas chronic pancreatitis. Thus, level patient sera potential function as diagnostic prognostic PC. However, measurement using conventional test platforms (e.g., enzyme linked...