A5070935610- Advanced X-ray Imaging Techniques
- Advanced Electron Microscopy Techniques and Applications
- Crystallography and Radiation Phenomena
- X-ray Spectroscopy and Fluorescence Analysis
- Particle Accelerators and Free-Electron Lasers
- Metal and Thin Film Mechanics
- Medical Imaging Techniques and Applications
- Laser-Plasma Interactions and Diagnostics
- Advanced Surface Polishing Techniques
- Diamond and Carbon-based Materials Research
- Semiconductor materials and devices
- Advancements in Photolithography Techniques
- Electron and X-Ray Spectroscopy Techniques
- Nuclear Physics and Applications
- Integrated Circuits and Semiconductor Failure Analysis
- Radiomics and Machine Learning in Medical Imaging
- Astronomical Observations and Instrumentation
- X-ray Diffraction in Crystallography
- Advanced Cellulose Research Studies
- Nanowire Synthesis and Applications
- Geological Modeling and Analysis
- Advanced ceramic materials synthesis
- Ion-surface interactions and analysis
- GaN-based semiconductor devices and materials
- Wood Treatment and Properties
MAX IV Laboratory
2017-2025
Lund University
2018-2025
Bhabha Atomic Research Centre
2021
Elkhorn Slough Foundation
2021
Université Grenoble Alpes
2021
Brookhaven National Laboratory
2014-2016
University of Göttingen
2005-2015
Helmholtz-Zentrum Berlin für Materialien und Energie
2010
Recent advances in coherent x-ray diffractive imaging have paved the way to reliable and quantitative of noncompact specimens at nanometer scale. Introduced a year ago, an advanced implementation ptychographic has removed much previous limitations regarding sample preparation illumination conditions. Here, we apply this recent approach toward structure determination nanoscale biological microscopy. We show that projected electron density unstained unsliced freeze-dried cells bacterium...
A compound optical system for coherent focusing and imaging at the nanoscale is reported, realised by high-gain fixed-curvature elliptical mirrors in combination with X-ray waveguide optics or different cleaning apertures. The key concepts are illustrated, as implemented Göttingen Instrument Nano-Imaging X-rays (GINIX), installed P10 coherence beamline of PETRA III storage ring DESY, Hamburg, examples typical applications biological given. Characteristic beam configurations recently achieved...
The propagation of hard X-ray synchrotron beams in waveguides with guiding layer diameters the 9–35 nm thickness range has been studied. planar waveguide structures consist an optimized two-component cladding. presented fabrication method is suitable for short and leak-proof slices lengths (along optical axis) sub-500 µm range, adapted transmission at photon energies 11.5–18 keV. A detailed comparison between finite-difference simulations optics experimental results presented, concerning...
Hard X-ray microscopy is a prominent tool suitable for nanoscale-resolution non-destructive imaging of various materials used in different areas science and technology. With an ongoing effort to push the 2D/3D resolution down 10 nm hard regime, both fabrication nano-focusing optics stability microscope using those become extremely challenging. In this work system designed constructed accommodate multilayer Laue lenses as nanofocusing presented. The developed apparatus has been thoroughly...
The NanoMAX hard X-ray nanoprobe is the first beamline to take full advantage of diffraction-limited storage ring at MAX IV synchrotron and delivers a high coherent photon flux for applications in diffraction imaging. Here, we characterize its focused beam using ptychographic analysis. We derive profiles energy range 6-22 keV estimate based on probe mode decomposition approach.
NanoMAX is the first hard X-ray nanoprobe beamline at MAX IV laboratory. It utilizes unique properties of world's operational multi-bend achromat storage ring to provide an intense and coherent focused beam for experiments with several methods. In this paper we present optics design in detail, show performance figures, give overview surrounding infrastructure diffraction endstation.
We have used x-ray waveguides as highly confining optical elements for nanoscale imaging of unstained biological cells using the simple geometry in-line holography. The well-known twin-image problem is effectively circumvented by a and fast iterative reconstruction. algorithm which combines classical Gerchberg-Saxton scheme hybrid-input-output optimized phase-contrast samples, well-justified at multi-keV photon energies. experimental allows quantitative phase reconstruction from single...
We developed a scanning hard x-ray microscope using new class of nano-focusing optic called multilayer Laue lens and imaged chromosome with nanoscale spatial resolution. The combination the x-ray's superior penetration power, high sensitivity to elemental composition, spatial-resolution quantitative analysis creates unique tool capabilities that other microscopy techniques cannot provide. Using this microscope, we simultaneously obtained absorption-, phase-, fluorescence-contrast images...
The diffraction endstation of the NanoMAX beamline is designed to provide high-flux coherent X-ray nano-beams for experiments requiring many degrees freedom sample and detector. equipped with high-efficiency Kirkpatrick-Baez mirror focusing optics a two-circle goniometer supporting positioning scanning device, carry compact environment. A robot used as detector arm. endstation, in continued development, has been user operation since summer 2017.
We have combined two high transmission planar x-ray waveguides glued onto each other in a crossed geometry to form an effective quasi-point source. From measurements of the far-field diffraction pattern, phase and amplitude near-field distribution is retrieved using error-reduction algorithm. In agreement with finite difference field simulations (forward calculation), reconstructed exit wave intensity (inverse calculation) exhibits full width at half maximum (FWHM) below 15 nm both...
We have imaged the three-dimensional density distribution of unstained and unsliced, freeze-dried cells gram-positive bacterium Deinococcus radiodurans by tomographic x-ray propagation microscopy, i.e. projection tomography with phase contrast formation free space propagation. The work extends previous imaging biological in simple in-line holography geometry to full reconstruction, based on a fast iterative reconstruction algorithm which circumvents usual twin-image problem. sample is...
We report on lensless nanoscale imaging using x-ray waveguides as ultra-small sources for quasi-point-like illumination. first give a brief account of the basic optical setup, an overview progress in waveguide fabrication and characterization, well basics image formation. then compare one-step holographic iterative ptychographic reconstruction, both simulated experimental data collected samples illuminated by waveguided beams. demonstrate that scanning sample with partial overlap can...
We report the commissioning of novel holography endstation for P10 coherence beamline at PETRA III DESY. The experimental imaging scheme is based on a highly coherent and divergent (cone) beam illumination, achieved by fixed‐curvature focusing mirrors with additional spatial filtering x‐ray waveguides. optical elements along path instrument in are described. First results shown.
We have studied the spatial coherence properties of a nano-focused x-ray beam by grating (Talbot) interferometry in projection geometry. The is focused fixed curvature mirror system optimized for high flux density under conditions partial coherence. divergent exit wave emitted from focus measured Talbot results are compared to numerical calculations propagation. In view imaging applications, magnified in-line image test pattern formed analyzed quantitatively. Finally, additional filtering...
We report on the fabrication and characterization of a wedged multilayer Laue lens for x-ray nanofocusing. The was fabricated using sputtering deposition technique, in which specially designed mask employed to introduce thickness gradient lateral direction multilayer. X-ray shows an efficiency 27% focus size 26 nm at 14.6 keV, good agreement with theoretical calculations. These results indicate that desired wedging is achieved structure. anticipate continuous development MLLs will advance...
This study employs computational algorithms to automatically identify and classify features in X‐Ray fluorescence (XRF) microscopy images. Principal component analysis (PCA) unsupervised machine learning algorithms, such as Gaussian mixture (GM) clustering, are implemented label on a collection of XRF maps human atherosclerotic plaque samples. The investigation involves the hard nanoprobe (NanoMAX) at MAX IV synchrotron radiation facility, utilizing scanning transmission (STXM) techniques....
We report on the fabrication and characterization of hard x-ray waveguide channels manufactured by e-beam lithography, reactive ion etching wafer bonding. The guiding layer consists air or vacuum cladding material silicon, which is favorable in view minimizing absorption losses. specifications for have to be met range achieve a suitable beam confinement two orthogonal directions are extremely demanding. First, high aspect ratios up 106 achieved between lateral structure size length guides....
We present results of a coherent x-ray diffractive imaging experiment performed on single colloidal crystal grain. The full three-dimensional (3D) reciprocal space map measured by an azimuthal rotational scan contained several orders Bragg reflections together with the interference signal between them. Applying iterative phase retrieval approach, 3D structure grain was reconstructed and positions individual particles were resolved. As result, exact stacking sequence hexagonal close-packed...
We present the design and instrumentation of a novel holography endstation for P10 coherence beamline at PETRA III DESY. The experimental imaging scheme is based on highly coherent divergent (cone) beam illumination, achieved by fixed curvature focusing mirrors with additional spatial filtering x‐ray waveguides. optical elements along path instrument under construction are described. Preliminary results obtained in similar setting comparable parameters given as benchmark, first simulations...
In this work, regenerated cellulose textile fibers, Ioncell-F, dry-wet spun with different draw ratios, have been investigated by scanning wide-angle X-ray scattering (WAXS) using a mesoscopic beam. The fibers were found to be homogeneous on the 500 nm length scale. Analysis of azimuthal angular dependence crystalline Bragg spot intensity revealed radial degree orientation crystallites that was increase distance from center fiber. We attribute velocity gradients during extrusion spin dope...
In the past decade Kirkpatrick-Baez (KB) mirrors have been established as powerful focusing systems in hard X-ray microscopy applications. Here a ptychographic characterization of KB focus dedicated nano-imaging setup GINIX (Göttingen Instrument for Nano-Imaging with X-rays) at P10 coherence beamline PETRA III synchrotron HASLYLAB/DESY, Germany, is reported. More specifically, it shown how aberrations beam, caused by imperfections height profile mirrors, can be eliminated using pinhole...
Abstract Axially heterostructured nanowires are a promising platform for next generation electronic and optoelectronic devices. Reports based on theoretical modeling have predicted more complex strain distributions increased critical layer thicknesses than in thin films, due to lateral relaxation at the surface, but understanding of growth these structures is hampered by lack high-resolution characterization techniques. Here, we demonstrate mapping an axially segmented GaInP-InP 190 nm...
The focusing and coherence properties of the NanoMAX Kirkpatrick–Baez mirror system at fourth-generation MAX IV synchrotron in Lund have been characterized. direct measurement nano-focused X-ray beams is possible by scanning an waveguide, serving basically as ultra-thin slit. In quasi-coherent operation, beam sizes down to 56 nm (FWHM, horizontal direction) can be achieved. Comparing measured Airy-like fringe patterns with simulations, degree |μ| has quantified a function secondary source...