Jennifer Chang

ORCID: 0000-0002-8381-3765
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About
Contact & Profiles
Research Areas
  • Influenza Virus Research Studies
  • Animal Disease Management and Epidemiology
  • Viral gastroenteritis research and epidemiology
  • Animal Virus Infections Studies
  • Respiratory viral infections research
  • CRISPR and Genetic Engineering
  • Insect Resistance and Genetics
  • Salivary Gland Tumors Diagnosis and Treatment
  • Plant Virus Research Studies
  • Orthopaedic implants and arthroplasty
  • Total Knee Arthroplasty Outcomes
  • Genomics and Phylogenetic Studies
  • Radiology practices and education
  • Impact of Technology on Adolescents
  • Ear and Head Tumors
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Bioinformatics and Genomic Networks
  • Interprofessional Education and Collaboration
  • Poetry Analysis and Criticism
  • Innovations in Medical Education
  • Radiation Dose and Imaging
  • Neurosurgical Procedures and Complications
  • Intracranial Aneurysms: Treatment and Complications
  • Nerve Injury and Rehabilitation
  • Vascular Malformations Diagnosis and Treatment

Agricultural Research Service
2022-2025

National Animal Disease Center
2018-2025

University of California, San Diego
2024-2025

Fred Hutch Cancer Center
2024

University of Washington
2024

Mississippi Delta Community College
2022-2023

Oak Ridge Associated Universities
2022-2023

Oak Ridge Institute for Science and Education
2022-2023

Iowa State University
2009-2023

Delta Air Lines (United States)
2022-2023

The Net Generation has adopted textisms as shortcuts in electronic communication. Two studies investigated whether the reported use of daily communication is related to quality writing. Seven hundred and eighteen young adults were queried about how often they used linguistic contextual textisms, instant messaging, monthly cell minutes, text messaging. In Study 1 wrote a formal letter company 2 asked write both provide an informal writing sample on happiness. Textism was quite low, finding...

10.1177/0093650210362465 article EN Communication Research 2010-04-07

Porcine reproductive and respiratory syndrome virus (PRRSV) continues to be a global challenge for swine health. Yim-Im et al. 2023 provides standard genetic nomenclature, extending previously published works better characterize PRRSV-2 ORF5-based lineages on scale. To facilitate the use of this scaffold sequences, including historical contemporary vaccines, were synthesized into dataset designed Nextclade v3.0. Metadata from sequences representing year, country, RFLP typing sequence...

10.3389/fvets.2024.1419340 article EN cc-by Frontiers in Veterinary Science 2024-09-13

The diversity of the 8 genes influenza A viruses (IAV) in swine reflects introductions from nonswine hosts and subsequent antigenic drift shift. Here, we curated a data set present pipeline that assigns evolutionary lineage genetic clade to query gene segments.

10.1128/mra.00673-19 article EN Microbiology Resource Announcements 2019-08-07

Background: Magnetic resonance imaging (MRI) has not been routinely used for infants with brachial plexus birth injury (BPBI); instead, the decision to operate is based on trajectory of clinical recovery by 6 months age. The aim this study was develop an MRI protocol that can be performed without sedation or contrast in order identify who would benefit from surgery at earlier age than which could made clinically. Methods: This prospective multicenter NAPTIME (Non-Anesthetized Plexus...

10.2106/jbjs.24.00561 article EN Journal of Bone and Joint Surgery 2025-01-29

ABSTRACT Influenza A virus (IAV) in swine the U.S. is surveilled to monitor genetic evolution inform intervention efforts and aid pandemic preparedness. We describe data from Department of Agriculture National Surveillance Plan for Virus Pigs 2009 2022. Clinical respiratory cases were subtyped followed by sequencing hemagglutinin (HA) neuraminidase (NA), a subset viruses whole genome sequenced. Phylogenetic analysis identified geographic temporal IAV reassortment hotspots. Regions acting as...

10.1101/2025.03.04.641516 preprint EN public-domain bioRxiv (Cold Spring Harbor Laboratory) 2025-03-05

Highly cross-linked formulations of ultrahigh-molecular-weight polyethylene (XLPE) offer exceptional wear resistance for total joint arthroplasty but are offset with a reduction in postyield and fatigue fracture properties comparison to conventional (UHMWPE). Oxidation is also an important property the longevity replacements (TJRs) as UHMWPE or XLPE utilizing radiation methods susceptible free radical generation subsequent embrittlement. The balance oxidation, wear, enduring concern...

10.1002/jbm.b.32887 article EN Journal of Biomedical Materials Research Part B Applied Biomaterials 2013-02-22

Abstract The neuraminidase (NA) and hemagglutinin (HA) are essential surface glycoproteins of influenza A virus (IAV). In this study, the evolution subtype N2 NA paired with H1 H3 HA in swine was evaluated to understand if genetic diversity were linked. Using time-scaled Bayesian phylodynamic analyses, relationships or from 2009 2018 evaluated. These data demonstrated increased relative within major clades circulating USA (N2.1998 between 2014 2017 N2.2002 2010 2016). Preferential pairing...

10.1093/ve/veab090 article EN cc-by Virus Evolution 2021-10-08

The first pandemic of the 21st century was caused by an H1N1 influenza A virus (IAV) introduced from pigs into humans, highlighting importance swine as reservoirs for viruses. Two major lineages H1 circulate in North America: 1A classical lineage (including that 2009 pandemic) and 1B human seasonal-like lineage. Here, we investigated evolution these IAV American their potential risk. We assessed antigenic distance between HA representative seasonal vaccine strains (1978 to 2015)...

10.1128/spectrum.01781-22 article EN cc-by Microbiology Spectrum 2022-11-01

In 2012, swine influenza surveillance detected a novel reassorted A virus (IAV) strain containing human-seasonal hemagglutinin (HA) and neuraminidase (NA). Subsequently, these viruses reassorted, maintaining only the human-origin H3, which resulted in new lineage of that became most frequently H3 clade US (2010.1 HA clade). Here, we assessed antigenic phenotype, virulence, transmission characteristics this following its introduction to swine. Relative 2010.1 from 2012 2014, recent...

10.1016/j.virol.2020.11.006 article EN cc-by-nc-nd Virology 2020-11-21

Influenza A virus (IAV) is passively surveilled in swine the United States through a U.S. Department of Agriculture administered surveillance system. We present an interactive Web tool to visualize and explore trends genetic geographic diversity IAV derived from

10.1128/mra.01081-21 article EN Microbiology Resource Announcements 2021-12-16

On September 17, 2017, the Maryland Department of Agriculture (MDA) was notified by fair and 4-H officials ill swine at agricultural A, held 14-17. That day, investigation 107 A revealed five with fever signs upper respiratory tract illness. All specimens collected from these tested positive for influenza virus MDA Animal Health Laboratory, A(H3N2) confirmed in all U.S. National Veterinary Services Laboratory (NVSL). 18, that exhibitors were also ill. alerted (MDH). joint MDH local health...

10.15585/mmwr.mm6742a1 article EN MMWR Morbidity and Mortality Weekly Report 2018-10-25

Influenza A viruses (IAV) sporadically transmit from swine to humans, typically associated with agricultural fairs in the United States. human seasonal H3 virus 2010-2011 IAV season was introduced into U.S. population and termed H3.2010.1 differentiate it previous virus. This H3N2 lineage became widespread commercial population, subsequently spilling over exhibition swine, caused a majority of variant (H3N2v) cases humans 2016 2017. cluster H3N2v were reported at an fair 2017 Ohio, where...

10.1128/jvi.01009-20 article EN Journal of Virology 2020-06-09

Abstract Helicoverpa zea (Lepidoptera: Noctuidae) is an insect pest of major cultivated crops in North and South America. The species has adapted to different host plants developed resistance several insecticidal agents, including Bacillus thuringiensis (Bt) proteins transgenic cotton maize. populations persist year-round tropical subtropical regions, but seasonal migrations into temperate zones increase the geographic range associated crop damage. To better understand genetic basis these...

10.1093/gbe/evac131 article EN cc-by-nc Genome Biology and Evolution 2022-08-12

Two separate introductions of human seasonal N2 neuraminidase genes were sustained in U.S. swine since 1998 (N2-98) and 2002 (N2-02). Herein, we characterized the antigenic evolution influenza A virus (IAV) across 2 decades following each introduction. The N2-98 N2-02 expanded genetic diversity, with two statistically supported monophyletic clades within lineage. To assess drift human-to-swine spillover events, generated a panel antisera against representative quantified distance between...

10.1128/jvi.00632-21 article EN Journal of Virology 2021-08-11

Introduction Cavernous sinus hemangiomas (CSHs) are rare, vascular, extra-axial tumors that diagnosed with a combination of imaging and biopsy. We describe the clinical presentations, findings, management two male patients CSHs. Case Report 1 describes 57-year-old man who presented vision changes cranial nerve palsies. Initial surgical biopsy were nondiagnostic. Follow-up Tc-99m tagged red blood cell (RBC) supported CSH diagnosis. He was treated resection radiotherapy. 2 chronic headache....

10.1055/s-0038-1641731 article EN cc-by-nc-nd Journal of Neurological Surgery Reports 2018-04-01

Human-to-swine transmission of influenza A virus (IAV) repeatedly occurs, leading to sustained and increased diversity in swine; human seasonal H3N2 introductions occurred the 1990s 2010s were maintained North American swine. Swine strains subsequently associated with zoonotic infections, highlighting need understand risk endemic swine IAV humans. We quantified antigenic distances between vaccine from 1973 2014 using a panel monovalent antisera raised pigs hemagglutination inhibition (HI)...

10.1128/jvi.01374-21 article EN Journal of Virology 2021-11-10

Long-read sequencing has revolutionized genome assembly, yielding highly contiguous, chromosome-level contigs. However, assemblies from some third generation long read technologies, such as Pacific Biosciences (PacBio) continuous reads (CLR), have a high error rate. Such errors can be corrected with short through process called polishing. Although best practices for polishing non-model de novo were recently described by the Vertebrate Genome Project (VGP) Assembly community, there is need...

10.1093/gbe/evad020 article EN cc-by Genome Biology and Evolution 2023-02-15

We present magnetic resonance imaging findings of an 11-year-old girl with a mammary analogue secretory carcinoma (MASC) the parotid gland. MASC is recently described tumor salivary glands that genetically and histologically similar to breast carcinoma. To date, few cases have been reported in pediatric population, limited information its characteristics. suggest decreased T2 signal solid component representing cellular components associated complex cystic parts may be helpful finding can...

10.1016/j.radcr.2020.05.035 article EN cc-by-nc-nd Radiology Case Reports 2020-07-03
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