A5003159043- Uterine Myomas and Treatments
- Cancer-related molecular mechanisms research
- Endometriosis Research and Treatment
- Ovarian cancer diagnosis and treatment
- Pregnancy and preeclampsia studies
- TGF-β signaling in diseases
- Circular RNAs in diseases
- Endometrial and Cervical Cancer Treatments
- Nanoplatforms for cancer theranostics
- Cervical Cancer and HPV Research
- RNA modifications and cancer
- Cancer Cells and Metastasis
- MicroRNA in disease regulation
- Neonatal Respiratory Health Research
- Cancer-related gene regulation
- Ion Transport and Channel Regulation
- Cancer Mechanisms and Therapy
- Extracellular vesicles in disease
- S100 Proteins and Annexins
- Ubiquitin and proteasome pathways
- Cancer, Lipids, and Metabolism
- Gynecological conditions and treatments
- Epigenetics and DNA Methylation
- Heat shock proteins research
- Birth, Development, and Health
Wenzhou Hospital of Traditional Chinese Medicine
2025
Wenzhou Medical University
2016-2025
Shanghai Electric (China)
2023-2024
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2016-2023
Nanchang University
2019-2023
First Affiliated Hospital of Nanchang University
2019-2023
Zhejiang University
2021
Jiangsu Cancer Hospital
2020
Chelsea and Westminster Hospital
2020
Imperial College London
2020
This study aimed to investigate the effects of quercetin on efficacy various chemotherapeutic drugs in cervical cancer cells.All drug experiments were performed HeLa and SiHa cells. The cell viability was detected by Cell Counting Kit-8 assay, proliferation estimated bromodeoxyuridine assay. CompuSyn software utilized calculate combination index (CI) evaluate synergistic or antagonistic effect with cisplatin, paclitaxel, 5-fluorouracil doxorubicin viability. migration invasion abilities...
Abstract Developing radiosensitizers based on the characteristics of tumor microenvironment can improve effectiveness and overcome bottleneck cervical cancer radiotherapy. Herein, an in situ synthesis strategy is demonstrated by using a highly bioactive zeolitic imidazolate framework to cap Mn 3 O 4 folic acid as targeting molecules (FA‐Mn @ZIF‐8) achieve enhanced radiosensitization against cancer. As expected, ZIF‐8 surface responds more effectively X‐rays. Meanwhile, facilitating presence...
Abstract Background Intestinal and perianal fistulas fissures are associated with significant morbidity decreased quality of life in patients Crohn’s disease (CD). We evaluated rates fistula fissure improvements upadacitinib (UPA), an oral selective Janus kinase inhibitor, CD who had or at baseline phase 3 induction maintenance trials. Methods In the U-EXCEL (NCT03345849) U-EXCEED (NCT03345836) trials, moderate-to-severe were randomized to UPA 45 mg once daily (QD) placebo (PBO) for 12...
Abstract Cervical cancer (CC) is a common gynecological malignancy. Despite the current screening methods have been proved effectively and significantly decreased CC morbidity mortality, deficiencies still exist. Single-cell RNA sequencing (scRNA-seq) approach can identify complex rare cell populations at single-cell resolution. By scRNA-seq, heterogeneity of tumor microenvironment across cervical carcinogenesis has mapped described. Whether these alterations could be detected applied to...
AIMTo investigate protective effects and molecular mechanisms of green tea polyphenols (GTP) on nonalcoholic fatty liver disease (NAFLD) in Zucker (ZF) rats. METHODSMale ZF rats were fed a high-fat diet (HFD) for 2 wk then treated with GTP (200 mg/kg) or saline (5 mL/kg) 8 wk, lean rat as their control.At the end experiment, serum tissue collected measurement metabolic parameters, alanine aminotransferase (ALT) aspartate
Objective: The purpose of this study was to explore whether human papillomavirus (HPV) DNA is present in surgical smoke generated by loop electrosurgical excision procedures (LEEPs). Furthermore, we investigated the impact HPV on surgeons. Methods: A total 134 outpatients with persistent infections treated LEEP for cervical intraepithelial neoplasia between 2015 and 2016, along corresponding operators, were included. flow fluorescence situ hybridization technique used detect exfoliated cells...
Understanding the role of N6-adenosine methylation (m6A) in tumor microenvironment (TME) is important since it can contribute to development. However, research investigating association between m6A and TME cervical cancer still its early stages. The aim this study was discover possible relationship RNA regulators, TME, PD-L1 expression levels, immune infiltration cancer. We gathered RNA-seq transcriptome data clinical information from patients using Cancer Genome Atlas (TCGA) Genotype-Tissue...