Xiao Yan

ORCID: 0000-0002-8407-8360
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About
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Research Areas
  • Advancements in Battery Materials
  • Advanced Battery Materials and Technologies
  • Advanced Battery Technologies Research
  • Supercapacitor Materials and Fabrication
  • Extraction and Separation Processes
  • Advanced battery technologies research
  • Gas Sensing Nanomaterials and Sensors
  • Laser-Matter Interactions and Applications
  • Advanced Fiber Laser Technologies
  • Analytical Chemistry and Sensors
  • Cold Atom Physics and Bose-Einstein Condensates
  • Tuberculosis Research and Epidemiology
  • Mycobacterium research and diagnosis
  • Quantum optics and atomic interactions
  • Electrocatalysts for Energy Conversion
  • Analytical Methods in Pharmaceuticals
  • Advanced Chemical Sensor Technologies
  • Metallurgical Processes and Thermodynamics
  • Recycling and Waste Management Techniques
  • MXene and MAX Phase Materials
  • Monoclonal and Polyclonal Antibodies Research
  • Galectins and Cancer Biology
  • Quantum Dots Synthesis And Properties
  • Advanced Biosensing Techniques and Applications
  • Advanced biosensing and bioanalysis techniques

Gannan Medical University
2025

First Affiliated Hospital of Gannan Medical University
2024-2025

Jiangsu Normal University
2017-2024

First Affiliated Hospital of Zhengzhou University
2008-2024

Beijing Institute of Technology
2024

The Seventh Affiliated Hospital of Sun Yat-sen University
2024

Sun Yat-sen University
2024

Grinm Advanced Materials (China)
2024

General Research Institute for Nonferrous Metals (China)
2024

Shenzhen Institute of Information Technology
2023

Pyrometallurgy technique is usually applied as a pretreatment to enhance the leaching efficiencies in hydrometallurgy process for recovering valuable metals from spent lithium-ion batteries. However, traditional pyrometallurgy processes are energy and time consuming. Here, we report carbothermal shock (CTS) method reducing LiNi0.3 Co0.2 Mn0.5 O2 (NCM325) cathode materials with uniform temperature distribution, high heating cooling rates, temperatures, ultrafast reaction times. Li can be...

10.1002/anie.202300074 article EN Angewandte Chemie International Edition 2023-02-14

To improve signal stability and quantitation, an optically stable, novel class of fluorophore for hybridization analysis human metaphase chromosomes is demonstrated. Detection sites in situ was based on fluorescence from streptavidin‐linked inorganic crystals cadmium selenide [(CdSe)ZnS]. Fluorescence nanocrystal fluorophores significantly brighter more photostable than organic Texas Red fluorescein. Thus, semiconductor offer a stable quantitative mode (FISH) research clinical applications.

10.1093/nar/gnh024 article EN Nucleic Acids Research 2004-02-13

Nanocarrier-based antibody targeting is a promising modality in therapeutic and diagnostic oncology. Single-walled carbon nanotubes (SWNTs) exhibit two unique optical properties that can be exploited for these applications, strong Raman signal cancer cell detection near-infrared (NIR) absorbance selective photothermal ablation of tumors. In the present study, we constructed HER2 IgY-SWNT complex demonstrated its dual functionality both destruction cells an vitro model consisting...

10.1186/1471-2407-9-351 article EN cc-by BMC Cancer 2009-10-02

The rapid growth of the nanotechnology industry and wide application various nanomaterials have raised concerns over their impact on environment human health. Yet little is known about mechanism cellular uptake cytotoxicity nanoparticles. An array has recently been introduced into cancer research promising for remarkable improvements in diagnosis treatment disease. Among them, quantum dots (QDs) distinguish themselves offering many intrinsic photophysical properties that are desirable...

10.1186/1477-3155-8-13 article EN cc-by Journal of Nanobiotechnology 2010-06-15

Li1.18Co0.15Ni0.15Mn0.52O2 cathode material was prepared by the sol–gel method. The coated with ionic conductor Li3VO4via direct reaction NH4VO3 at 350 °C. Li3VO4 had a higher ordered hexagonal layered structure, and less Li+/Ni2+ cation mixing. surface of composed polycrystals, which were impregnated into bulk active material. coating protected from contact CO2 in air, thus inhibiting formation an Li2CO3 layer. Electrochemical studies showed that improved activation Mn4+ ions, resulting...

10.1039/c4ta00189c article EN Journal of Materials Chemistry A 2014-01-01

Sepsis is an excessive inflammatory condition with a high mortality rate and limited prediction therapeutic options. In this study, for the first time, to our knowledge, we found that downregulation and/or blockade of T cell Ig mucin domain protein 3 (Tim-3), negative immune regulator, correlated severity sepsis, suggesting Tim-3 plays important roles in maintaining homeostasis sepsis both humans mouse model. Blockade led increased macrophage activation, which contributed systemic response...

10.4049/jimmunol.1202661 article EN The Journal of Immunology 2013-01-31

Efficient catalysts are needed to accelerate the conversion and suppress shuttling of polysulfides (LiPSs) promote further development lithium–sulfur (Li–S) batteries. Intermetallic niobium boride (NbB2) has indefinite potential due superior catalytic activity. Nonetheless, lack a rational understanding catalysis creates challenge for design catalysts. Herein, NbB2/reduced graphene oxide-modified PP separator (NbB2/rGO/PP) is rationally designed. Essential, an in-depth insight into mechanism...

10.1021/acsnano.3c12076 article EN ACS Nano 2024-02-28

Abstract Aberrant promoter hypermethylation of tumor suppressor genes is proposed to be a common feature primary cancer cells. We recently developed pharmacological unmasking microarray approach screen unknown gene candidates epigenetically silenced in human cancers. In this study, we applied method identify such head and neck squamous cell carcinoma (HNSCC). identified 12 novel methylated HNSCC lines, including PGP9.5, cyclin A1, G0S2, bone-morphogenetic protein 2A, MT1G, neuromedin U,...

10.1158/0008-5472.can-04-0993 article EN Cancer Research 2004-09-01

Pure anatase TiO2 and N-doped nanoparticles were prepared by a solvothermal method. X-ray photoelectron spectroscopy showed that the surface of doped material was dominated interstitial N, while substitutional N coexisted in bulk. Both materials superior cycle stability. In addition, exhibited much better rate capability than pure TiO2. A discharge capacity 45 mAh g–1 obtained at 15 C rate, which 80% higher The electrochemical kinetic properties studied galvanostatic intermittent titration...

10.1021/am5002053 article EN ACS Applied Materials & Interfaces 2014-03-05

T cell Ig mucin-3 (Tim-3), an immune checkpoint inhibitor, shows therapeutic potential. However, the molecular mechanism by which Tim-3 regulates responses remains to be determined. In particular, very little is known about how works in innate cells. Here, we demonstrated that involved development of tumor-promoting M2 macrophages colon cancer. Manipulation pathway significantly affected polarization status intestinal and progression The signaling was explored using microarray,...

10.1080/2162402x.2016.1211219 article EN OncoImmunology 2016-08-03

A TiO<sub>2</sub>–bronze/N-doped graphene nanocomposite was prepared by a facile method. The material exhibits outstanding rate capacity. high reversible capacity of 101.6 mA h g<sup>−1</sup>is obtained at the 100C rate, indicating its great potential for use in power lithium ion batteries.

10.1039/c4ta06361a article EN Journal of Materials Chemistry A 2015-01-01

A facile synthesis method for reduced graphene oxide wrapped mesoporous TiO<sub>2</sub> mircospheres, which show excellent electrochemical performance, at 60 C rate, and a high discharge capacity of 83.6 mA h g<sup>−1</sup>.

10.1039/c3nr06393c article EN Nanoscale 2014-01-01

The substituted-N plays a key role in improving the conductivity and structural stability of TiO<sub>2</sub>-B. Thereout, rate capability cycling TiO<sub>2</sub>-B nanowires are significantly improved.

10.1039/c5nr02457a article EN Nanoscale 2015-01-01

Abstract: As a potent therapeutic agent, small interfering RNA (siRNA) has been exploited to silence critical genes involved in tumor initiation and progression. However, development of desirable delivery system is required overcome the unfavorable properties siRNA such as its high degradability, molecular size, negative charge help increase accumulation tissues promote efficient cellular uptake endosomal/lysosomal escape nucleic acids. In this study, we developed new activatable...

10.2147/ijn.s129574 article EN cc-by-nc International Journal of Nanomedicine 2017-03-01

The limitation of a high-voltage lithium (Li) metal battery lies in the absence robust electrolyte that can endure oxidation loss at cathode and suppress dendrite growth Li anode.

10.1039/c8ta09380f article EN Journal of Materials Chemistry A 2018-11-28

The molecular mechanism of lactoferrin-induced cell growth inhibition is incompletely understood. Studying head and neck cancer cells treated with human lactoferrin, we observed arrest in three four lines tested. This was caused by cycle at the G0-G1 checkpoint. Lactoferrin-induced associated a large increase p27 protein, accompanied decreased phosphorylation retinoblastoma suppression cyclin E. Decreased levels phosphorylated Akt were also lactoferrin-sensitive after treatment. These...

10.1158/1078-0432.ccr-04-0988 article EN Clinical Cancer Research 2004-12-15

ZnO/α-Fe2O3 composites built from plenty of ZnO nanoparticles decorated on the surfaces uniform round-edged α-Fe2O3 hexahedrons were successfully prepared via a facile solvothermal method. Various techniques employed to obtain crystalline and morphological characterization as-prepared samples. In addition, comparative sensing performance investigation between two kinds materials clearly demonstrated that properties substantially enhanced compared with those single component, which manifest...

10.1021/acsami.5b01071 article EN ACS Applied Materials & Interfaces 2015-04-13

We report a novel composite of fluorine-doped carbon-decorated LiMn0.75Fe0.25PO4 (LMFP) nanoplates synthesized via facile method by using hybrid sucrose and polyvinylidene fluoride as carbon fluorine sources. In the composite, thin LMFP expose large amounts (010) crystal face which shortens Li+ ion diffusion distance. Also, coating layer can provide sufficient pathway for rapid electron transport, partially formed metal fluorides in interface between surface will help reduce charge transfer...

10.1021/acssuschemeng.6b03163 article EN ACS Sustainable Chemistry & Engineering 2017-04-20
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