- Nanoplatforms for cancer theranostics
- Electrospun Nanofibers in Biomedical Applications
- Viral gastroenteritis research and epidemiology
- Alzheimer's disease research and treatments
- Mesoporous Materials and Catalysis
- Hematopoietic Stem Cell Transplantation
- Immunotherapy and Immune Responses
- Animal Virus Infections Studies
- Advanced Nanomaterials in Catalysis
- Catalytic Processes in Materials Science
- Endometrial and Cervical Cancer Treatments
- Cancer, Hypoxia, and Metabolism
- Graphene and Nanomaterials Applications
- Tissue Engineering and Regenerative Medicine
- Trace Elements in Health
- Traditional Chinese Medicine Analysis
- Cancer, Lipids, and Metabolism
- Acute Ischemic Stroke Management
- Gold and Silver Nanoparticles Synthesis and Applications
- Cerebrovascular and Carotid Artery Diseases
- Immune Cell Function and Interaction
- Cancer Immunotherapy and Biomarkers
- RNA Interference and Gene Delivery
- Advanced MIMO Systems Optimization
- Cooperative Communication and Network Coding
Jilin University
2015-2025
First Hospital of Jilin University
2018-2025
Wenzhou University
2023-2025
WinnMed
2024-2025
China Agricultural University
2025
Shanghai Tenth People's Hospital
2024
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2021-2024
Tongji University
2024
State Key Laboratory on Integrated Optoelectronics
2023-2024
Second Hospital of Tianjin Medical University
2024
Abstract Although colloidal perovskite nanocrystal (PNC) solution has exhibited near‐unity photoluminescence quantum yield (PLQY), the luminance would be severely quenched when PNC is assembled into thin films due to agglomeration and fusion of NCs caused by exfoliation surface ligands non‐radiative Förster resonance energy transfer (FRET) from small large particle sizes, which seriously affected performances light‐emitting diodes (LEDs). Here, we used Guanidine thiocyanate (GASCN) Sodium...
Abstract The earthworm is particularly fascinating to biologists because of its strong regenerative capacity. However, many aspects regeneration in nature remain elusive. Here we report chromosome-level genome, large-scale transcriptome and single-cell RNA-sequencing data during ( Eisenia andrei ) regeneration. We observe expansion LINE2 transposable elements gene families functionally related (for example, EGFR , epidermal growth factor receptor) for genes exhibiting differential expression...
Pure anatase TiO2 and N-doped nanoparticles were prepared by a solvothermal method. X-ray photoelectron spectroscopy showed that the surface of doped material was dominated interstitial N, while substitutional N coexisted in bulk. Both materials superior cycle stability. In addition, exhibited much better rate capability than pure TiO2. A discharge capacity 45 mAh g–1 obtained at 15 C rate, which 80% higher The electrochemical kinetic properties studied galvanostatic intermittent titration...
Alzheimer's disease (AD) is the most common type of presenile and senile dementia. The human β-amyloid precursor cleavage enzyme (BACE-1) a key responsible for amyloid plaque production, which implicates progress symptoms AD. Here we assessed anti-BACE-1 behavioral activities curcuminoids from rhizomes Curcuma longa (Zingiberaceae), diarylalkyls curcumin (CCN), demethoxycurcumin (DMCCN), bisdemethoxycurcumin (BDMCCN) against AD Drosophila melanogaster models.Neuro-protective ability was...
The purpose of this study was to evaluate both in vitro and vivo anticancer activities against colorectal cancer (CRC) electrospun polylactide (PLA) nanofibers loaded with 5-fluorouracil (5-Flu) oxaliplatin. For evaluation, human CRC HCT8 cells were directly exposed the drug-loaded fiber mats, followed MTT flow cytometry (FCM) assay. mats locally implanted into mouse CT26 tumor-bearing mice, histological analysis detection survival rate. results showed that similar combination free 5-Flu...
Human studies report conflicting results on the predictive power of serum lipids progression chronic kidney disease (CKD). We aimed to systematically identify that predict end-stage disease.From Chronic Renal Insufficiency Cohort, 79 patients with CKD stage 2 3 who progressed ESKD over 6 years follow up were selected and frequency-matched by age, sex, race, diabetes 121 non-progressors less than 25% decline in estimated glomerular filtration rate (eGFR) during up. The randomly divided into...
To investigate the top late-onset Alzheimer disease (LOAD) risk loci detected or confirmed by International Genomics of Alzheimer's Project for association with brain gene expression levels to identify variants that influence (AD) through regulation.Expression from cerebellum (CER) and temporal cortex (TCX) were obtained using Illumina whole-genome cDNA-mediated annealing, selection, extension, ligation assay (WG-DASL) ∼400 autopsied patients (∼200 AD ∼200 non-AD pathologies). We tested 12...
Abstract Metal nanoclusters (NCs) are well‐recognized novel nano‐agents that hold great promise for applications in nanomedicine because of their ultrafine size, low toxicity, and high renal clearance. As foreign substances, however, an in‐depth understanding the bioresponses to metal NCs is necessary but still far from being realized. Herein, this review deployed summarize biofates at various biological levels, emphasizing multiscale molecular, cellular, organismal levels. In parts‐to‐whole...
Electrospun nanofibers co-loaded with cisplatin and curcumin effectively reduce the risk of local cervical cancer recurrence after surgery.
ABSTRACT Background The safety and immunogenicity of heterologous prime-boost COVID-19 vaccine regimens with one shot a recombinant adenovirus type-5-vectored Convidecia has not been reported. Methods We conducted randomized, controlled, observer-blinded trial immunization CoronaVac in healthy adults 18-59 years age. Eligible participants who were primed or two doses randomly assigned at 1:1 ratio to receive booster dose CoronaVac. Participants masked the received but three-dose two-dose...