Wenbin Wu

ORCID: 0000-0002-8183-1687
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About
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Research Areas
  • Congenital Diaphragmatic Hernia Studies
  • Tracheal and airway disorders
  • Lung Cancer Diagnosis and Treatment
  • Esophageal and GI Pathology
  • Esophageal Cancer Research and Treatment
  • Pleural and Pulmonary Diseases
  • Energy Efficient Wireless Sensor Networks
  • Lymphatic Disorders and Treatments
  • Lung Cancer Research Studies
  • Cancer Diagnosis and Treatment
  • Mobile Ad Hoc Networks
  • Medical Imaging and Pathology Studies
  • Lung Cancer Treatments and Mutations
  • Myasthenia Gravis and Thymoma
  • Network Traffic and Congestion Control
  • Security in Wireless Sensor Networks
  • Metastasis and carcinoma case studies
  • Oral and Maxillofacial Pathology
  • Trauma Management and Diagnosis
  • RNA Interference and Gene Delivery
  • Brain Metastases and Treatment
  • Genetic Mapping and Diversity in Plants and Animals
  • Cardiac, Anesthesia and Surgical Outcomes
  • Advanced Radiotherapy Techniques
  • Complex Network Analysis Techniques

Xuzhou Central Hospital
2014-2023

Southeast University
2002-2022

Xuzhou Medical College
2020-2022

Rice Research Institute
2022

Zhejiang University
2014-2020

Weatherford College
2018-2020

Alibaba Group (China)
2020

Wenzhou Medical University
2019

Ruian People's Hospital
2019

Yidu Central Hospital of Weifang
2017

For the treatment of unresectable liver cancer or for prevention post-surgery tumor recurrence, local chemotherapy is probably a good choice. A pilot study was carried out to examine efficacy doxorubicin-loaded polylactide electrospun nanofibers (Dox fibers) as system against secondary hepatic carcinoma (SHCC). Two orthotopic SHCC models were prepared by injecting murine mammary EMT6 cells into left lobe and portal vein Balb/c mice, resulting in nodular diffuse (NSHCC DSHCC), respectively....

10.1039/c2tb00121g article EN Journal of Materials Chemistry B 2012-11-01

A functionalized six-membered cyclic carbonate monomer containing a protected thiol group, 2-(2,4-dinitrophenylthio)ethyl-5-methyl-2-oxo-1,3-dioxane-5-carboxylate (MTC), was prepared. Ring-opening polymerization (ROP) of MTC and L-lactide (LA) initiated by monohydroxyl poly(ethylene glycol) (mPEG) successfully performed with controlled polymer molecular weight distribution. The structures the obtained copolymers were confirmed NMR FTIR. After deprotection under mild conditions, amphiphilic...

10.1039/c2py20240a article EN Polymer Chemistry 2012-01-01

To determine the clinical efficacy of preoperative coil localization-guided video-assisted thoracoscopic surgery (VATS) for lung nodules.Between November 2015 and July 2017, 56 patients with nodules underwent VATS procedure. The implantation was performed under guidance computed tomography (CT). end tail remained above visceral pleura. target were removed by wedge resection. Data on technical success localization resection, procedure-related complications, pathological results collected...

10.1089/lap.2017.0484 article EN Journal of Laparoendoscopic & Advanced Surgical Techniques 2017-11-14

Local tumor recurrence after cervical cancer surgery remains a clinical problem. Vaginal delivery of thermosensitive hydrogel may be suited to reduce relapse rate with more efficacy and safety. A pilot study was carried out evaluate the carboplatin-loaded poloxamer prevent local surgery. In vivo vaginal retention evaluation 27% in mice proven suitable drug formulation due its low gelation temperature. mimic orthotopic cervical/vaginal model established by injecting murine cell line U14 into...

10.1080/10717544.2016.1205158 article EN Drug Delivery 2016-06-24

The efficacy and specificity of treatment are the major challenges for cancer gene therapy. Oncolytic virotherapy is an attractive drug delivery platform Previous studies have determined that apoptin a p53-independent, Bcl-2-insensitive apoptotic protein has ability to induce apoptosis specifically in tumor cells. In this study, we show administration dual cancer-specific oncolytic adenovirus construct, Ad-hTERT-E1a-apoptin [in which early region 1a (E1a) driven by promoter human telomerase...

10.3892/ijmm.2012.1077 article EN International Journal of Molecular Medicine 2012-07-25

Inferring fine-grained link metrics by using aggregated path measurements, known as network tomography, is an effective and efficient way to facilitate various operations, such monitoring, load balancing, failure diagnosis. Given the topology a set of interesting links, we study problem calculating these links end-to-end cycle-free measurements among selected monitors, i.e., preferential tomography. Since assigning nodes monitors usually requires non-negligible operational cost, focus on...

10.1109/tnet.2016.2581176 article EN IEEE/ACM Transactions on Networking 2016-06-30

Objective Mature hair follicles represent an important stage of follicle development, which determines the stability structure and its ability to enter cycle. Here, we used weighted gene co-expression network analysis (WGCNA) identify hub genes mature skin in Inner Mongolian cashmere goats. Methods We transcriptome sequencing data for goats from fetal days 45–135 days, divided co expressed into different modules by WGCNA. Characteristic values were screen out that highly follicles. Module...

10.1371/journal.pone.0243507 article EN cc-by PLoS ONE 2020-12-22

Background: Esophageal cancer is recognized as one of the most refractory pernicious diseases. In addition, it an aggressive malignancy with a propensity for local progression and distant dissemination. Because poor long-term prognosis patients esophageal cancer, increasing attention has focused on integration targeted agents into current therapeutics. Nevertheless, there have been few studies reported concerning therapeutic efficacy paclitaxel-conjugated polymeric micelles in human vivo....

10.2147/ijn.s32620 article EN cc-by-nc International Journal of Nanomedicine 2012-07-01

Hepatocellular carcinoma shows low response to most conventional chemotherapies; additionally, extrahepatic metastasis from hepatoma is considered refractory systemic chemotherapy. Target therapy a promising strategy for advanced hepatoma; however, targeted accumulation and controlled release of therapeutic agents into the metastatic site still great challenge. Folic acid (FA) paclitaxel (PTX) containing composite micelles (FA-M[PTX]) were prepared by coassembling FA polymer conjugate PTX...

10.2147/ijn.s57744 article EN cc-by-nc International Journal of Nanomedicine 2014-04-01

Inferring per-link metrics through aggregated path measurements, known as network tomography, is an effective way to facilitate various operations, such monitoring, load balancing, and fault diagnosis. We study the problem of identifying additive link a set interesting links from end-to-end cycle-free measurements among selected monitors, i.e., preferential tomography. Since assigning node monitor usually requires non-negligible operational cost, we focus on minimum number monitors (i.e.,...

10.1109/tnet.2015.2411691 article EN IEEE/ACM Transactions on Networking 2015-04-03

Competency in video-assisted thoracoscopic surgery (VATS) lobectomy is estimated to be reached after 50 cases. Preoperative identification of individualized pulmonary vascular drainage essential for the safe and fluent performance single-direction uniportal VATS (UVATS) anatomic lobectomy. Digital anatomy models established by three-dimensional computed tomography bronchography angiography (3D-CTBA) therefore utilized accumulate variations right upper lobe (RUL) veins, as considered most...

10.21037/atm.2019.09.135 article EN Annals of Translational Medicine 2019-10-01

The purpose of this study was to explore the mechanism miR-375/XPR1 axis in esophageal squamous cell carcinoma (ESCC) and provide a new idea for targeted therapy ESCC.Differentially expressed genes GEO TCGA databases were analyzed by bioinformatics. expression levels miR-375 XPR1 mRNA detected qRT-PCR. Protein western blot. Bioinformatics analysis dual luciferase assay conducted confirm target relationship between XPR1. viability, proliferation, migration invasion cells each treatment group...

10.2174/1566523220666201229155833 article EN Current Gene Therapy 2020-12-29

Recent wireless sensor networks (WSNs) are becoming increasingly complex with the growing network scale and dynamic nature of communications. Many measurement diagnostic approaches depend on per-packet routing paths for accurate fine-grained analysis behaviors. In this paper, we propose iPath, a novel path inference approach to reconstructing in large-scale networks. The basic idea iPath is exploit high similarity iteratively infer long from short ones. starts an initial known set performs...

10.1109/tnet.2014.2371459 article EN IEEE/ACM Transactions on Networking 2014-12-06

A new dedicated resource allocation method for D2D communications in cellular systems employing fractional frequency reuse (FFR) is proposed this paper. This consists of three steps. For the first step, permitted set each link determined. second a assignment algorithm which takes both interference and load into considerations. third slot scheduling relies on maximum weight independent graph theory. Simulation results show efficiency method.

10.1109/wcsp.2014.6992029 article EN 2014-10-01

Timely treatment of premenstrual syndrome (PMS) is not always available for rural women, because the local medical resources are insufficient. The efficacy remote intervention by smartphone on PMS has been confirmed. A retrospective analysis was performed patients between January 2014 and December 2015. After a propensity score matched analysis, 60 were enrolled evenly divided into group outpatient group. Multidisciplinary therapy including cognitive-behavioral (CBT), oral medication,...

10.1097/md.0000000000011629 article EN cc-by-nc Medicine 2018-07-01

Objective The present study aimed to elucidate the underlying pathogenesis of Kawasaki disease (KD) and identify potential biomarkers for KD. Methods Gene expression profiles GSE68004 dataset were downloaded from Expression Omnibus database. pathways functional annotations differentially expressed genes (DEGs) in KD examined by Ontology Kyoto Encyclopedia Genes Genomes pathway enrichment analyses using Database Annotation, Visualization Integrated Discovery (DAVID) tool. Protein–protein...

10.1177/0300060519862057 article EN cc-by-nc Journal of International Medical Research 2019-08-07
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