A5009547090- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gallbladder and Bile Duct Disorders
- Medical Imaging and Pathology Studies
- Adrenal and Paraganglionic Tumors
- Atomic and Subatomic Physics Research
- Liver Disease and Transplantation
- Medical Imaging Techniques and Applications
- Hormonal Regulation and Hypertension
- Organ Transplantation Techniques and Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Advanced Radiotherapy Techniques
- Pleural and Pulmonary Diseases
- Tracheal and airway disorders
- Advanced Neuroimaging Techniques and Applications
- Gastric Cancer Management and Outcomes
- Lung Cancer Treatments and Mutations
- Functional Brain Connectivity Studies
- Biliary and Gastrointestinal Fistulas
- Liver Disease Diagnosis and Treatment
- Esophageal and GI Pathology
- Pediatric Hepatobiliary Diseases and Treatments
- Abdominal vascular conditions and treatments
- Cytokine Signaling Pathways and Interactions
Xuzhou Central Hospital
2015-2025
First Affiliated Hospital Zhejiang University
2024
Zhejiang Chinese Medical University
1999-2024
Huangshi Central Hospital
2019-2023
Hubei Polytechnic University
2019-2023
University of Glasgow
2023
Air Force Medical University
2020-2023
East China Normal University
2023
Hefei University of Technology
2021-2022
Xuzhou Medical College
2014-2022
The purpose of this study is to explore the expression miRNA-590-5p, an exosome gastric cancer (GC), and evaluate suitability miR-590-5p, with its own clinical characteristics. Serum samples from 168 patients 50 matched controls were collected exosomal RNAs extracted. After that, miR-590-5p analyzed by quantitative polymerase chain reaction (qRT-PCR), which more related pathological parameters patient monitoring data. MGC-803 HGC-27 cells treated mimics, then changes cell fluidity...
// Fanfan Zhu 1, * , Chunyan Dai Yufei Fu Jacky F.C. Loo 2 Dajin Xia 3 Sizhi P. Gao 4 Zhongjun Ma 5 Zhe Chen 1 Zhejiang Key Laboratory of Gastro-Intestinal Pathophysiology, Hospital Traditional Chinese Medicine, Medical University, Hangzhou, PR China Biochemistry Program, School Life Sciences, The University Hong Kong, Kong Public Health, Zijingang Campus, HOPP, Memorial Sloan Kettering Cancer Center, New York, NY, USA Institute Marine Biology and Natural Products, Ocean College, These...
Drug resistance is a major challenge for chemotherapy in treating human gastric cancer (GC), as the underlying molecular mechanism of chemoresistance GC remains unknown. Caveolin-1 (Cav-1) scaffold protein plasma membrane caveolae that acts tumor modulator by interacting with several cell signals. In this research, we showed survival rate cells to cisplatin (CDDP) increased presence Cav-1. Moreover, Cav-1 overexpression inhibited cisplatin-induced apoptosis and improved cells. knock-down...
Abstract Background To assess relative safety and diagnostic performance of low- standard-dose computed tomography (CT)-guided biopsy for pulmonary nodules (PNs). Materials methods This was a single-center prospective randomized controlled trial (RCT). From June 2020 to December 2020, consecutive patients with PNs were randomly assigned into or groups. The primary outcome diagnosis accuracy. secondary outcomes included technical success, yield, operation time, radiation dose, biopsy-related...
Abstract Background Inflammation has been implicated in the pathology of schizophrenia and may cause neuronal cell death dendrite loss. Neuroimaging studies have highlighted longitudinal brain structural changes patients with schizophrenia, yet it is unclear whether this related to inflammation. We aim address question, by relating transcriptional profile inflammation markers early stage schizophrenia. Methods Thirty-eight first-episode 51 healthy controls were included. High-resolution...
While there have been prior reports on pulmonary nodule (PN) localization through computed tomography (CT)-guided soft hook-wire (SHW) placement, remains a dearth of studies specifically focused the CT-guided SHW multiple PNs. This study was thus designed to evaluate efficacy and safety this strategy in patients with In total, 43 consecutive PNs underwent followed by video-assisted thoracoscopic surgery (VATS) resent these our hospital between January 2022 December 2022. A control group...
The goal of this study is to determine the feasibility, diagnostic accuracy, and risk factor complications computed tomography (CT)-guided percutaneous cutting needle biopsy (PCNB) for small lung nodules.From January 2014 May 2015, 141 patients with nodule were performed CT-guided PCNB procedure. Data on technical success, complication collected analyzed.Technical success nodules was 100%. A total punctured. mean time procedure 15.7 ± 4.3 minutes. results included malignancy (n = 79),...
To determine the clinical efficacy of preoperative coil localization-guided video-assisted thoracoscopic surgery (VATS) for lung nodules.Between November 2015 and July 2017, 56 patients with nodules underwent VATS procedure. The implantation was performed under guidance computed tomography (CT). end tail remained above visceral pleura. target were removed by wedge resection. Data on technical success localization resection, procedure-related complications, pathological results collected...
Lung cancer is the leading cause of cancer-related death worldwide. Epithelial-mesenchymal transition (EMT) promotes lung progression and metastasis, especially in adenocarcinoma. Sex determining region Y-box protein 5 (SOX5) known to stimulate various cancers. Here, we used immunohistochemical analysis reveal that SOX5 levels were increased 90 adenocarcinoma patients. The high expression non-tumor counterparts correlated with patients' poor prognosis. Inhibiting attenuated metastasis cells,...
Video-assisted thoracoscopic surgery (VATS) has been widely used for diagnostic wedge resection of lung nodules. When VATS is performed multiple nodules, preoperative localization each target nodule required. In this study, we evaluated the clinical effectiveness computed tomography (CT)-guided simultaneous coil in one-stage nodules.Between November 2015 to March 2018, 19 patients with nodules underwent CT-guided and at our center. Data on technical success resection, complications,...
Abstract Introduction The differentiation of benign and malignant sub‐centimetre (≤10 mm) lung nodules (SCLNs) is challenging. Computed tomography (CT)‐guided biopsy has been widely used for the diagnosis or masses. However, studies regarding CT‐guided biopsies SCLNs are still lacking. Objectives To evaluate feasibility diagnostic accuracy SCLNs. Methods From December 2011 to October 2017, 102 patients with underwent biopsies. Data on technical success, performance procedure‐related...
Abstract Background Preoperative computed tomography (CT)-guided localization has been shown to significantly improve lung nodule video-assisted thoracoscopic surgery (VATS)-based wedge resection technical success rates. However, at present, there was insufficient research regarding the optimal approaches of these nodules prior resection. We aimed compare relative clinical efficacy preoperative CT-guided methylene blue and coil-based localization. Methods In total, 91 patients with were...
Abstract Multimodal neuroimaging features provide opportunities for accurate classification and personalized treatment options in the psychiatric domain. This study aimed to investigate whether brain predict responses overall of schizophrenia at end first or a single hospitalization. Structural functional magnetic resonance imaging (MRI) data from two independent samples ( N = 85 63, separately) patients baseline were included. After treatment, classified as responders non‐responders....
Purpose: This study aims to ascertain the relative outcomes in patients with hilar cholangiocarcinoma (HCCA) undergoing either unilateral or bilateral self-expanded metallic stent (SEMS) insertion. Materials and Methods: In this retrospective single-center study, 93 HCCA were treated through percutaneous insertion of SEMS during January 2012 December 2018. We compared technical success, clinical long-term treatment method. Results: Overall, 51 42 insertion, respectively, success rates 92.2%...
Angiogenesis is the main cause of lung adenocarcinoma (LAC) poor prognosis. This study aimed to investigate effect sex-determining region Y-box protein 5 (SOX5) expression on angiogenesis LAC and explore its possible mechanism.The was tested by tube formation assays using human umbilical vein endothelial cells cocultured with A549 cells. Lentivirus shRNA SOX5 lentivirus overexpression system were used establish cell lines, which expressed different levels. downstream signaling targets...