A5058856546- Hepatitis B Virus Studies
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Nuclear physics research studies
- Nuclear Physics and Applications
- Traditional Chinese Medicine Studies
- Neurological Disease Mechanisms and Treatments
- Drug-Induced Hepatotoxicity and Protection
- Acute Ischemic Stroke Management
- Traditional Chinese Medicine Analysis
- Pediatric Hepatobiliary Diseases and Treatments
- Tryptophan and brain disorders
- Gallbladder and Bile Duct Disorders
- Folate and B Vitamins Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Air Quality and Health Impacts
- Pharmacological Effects of Natural Compounds
- Stress Responses and Cortisol
- Diabetes Treatment and Management
- Paraquat toxicity studies and treatments
- Iron Metabolism and Disorders
- Pregnancy and preeclampsia studies
- Gut microbiota and health
- Ginger and Zingiberaceae research
- Occupational and environmental lung diseases
China Institute of Atomic Energy
2001-2025
Binzhou University
2014-2024
Binzhou Medical University
2014-2024
State Key Laboratory of Digital Medical Engineering
2021-2024
Southeast University
2021-2024
First Affiliated Hospital of Zhengzhou University
2015-2024
North China University of Science and Technology
2024
Chengdu University of Traditional Chinese Medicine
2010-2023
Southwest Medical University
2023
Shanghai Jiao Tong University
2023
Growing evidence suggests that there are similar pathological mechanisms and closely related pathogenic risk factors for inflammatory bowel disease (IBD) Parkinson's (PD). However, the epidemiological features of these two diseases different. This review systematically evaluated relationship between risk. We searched PubMed, Embase, Cochrane databases to retrieve observational studies IBD PD published from inception October 2019. Nine studies, involving 12,177,520 patients, were included in...
To investigate the efficacy and tolerability of albiglutide, a weekly glucagon-like peptide-1 receptor agonist, when added to metformin glimepiride in triple therapy regimen people with type 2 diabetes mellitus.This was 156-week, randomized, double-blind, parallel-group, multicentre study. In present paper we describe primary results, namely those at 52 weeks. Adult participants (n = 685) were randomly assigned albiglutide (30 mg/week), pioglitazone mg/day) or placebo. If needed, blinded...
The present study investigates whether paraquat (PQ) regulates polarization of alveolar macrophages through glycolysis and promotes the occurrence acute lung injury in rats. In vivo, PQ intraperitoneal injection was used to construct a model vitro, measured effect different concentrations on viability macrophages, explored metabolism at time points after intervention. Compared with normal control (NC) group, pathological damage rats increased gradually poisoning, reaching significant degree...
The transfer reactions of ${}^{11}\mathrm{B}{(d,p)}^{12}\mathrm{B}$ and ${}^{12}\mathrm{C}{(d,p)}^{13}\mathrm{C},$ at incident energy $11.8 \mathrm{MeV},$ have been used to extract asymptotic normalization coefficients root-mean-square radii for the last neutron in ${}^{12}\mathrm{B}$ ${}^{13}\mathrm{C}.$ It is found experimentally that second ${(J}^{\ensuremath{\pi}}{=2}^{\ensuremath{-}})$ third ${(J}^{\ensuremath{\pi}}{=1}^{\ensuremath{-}})$ excited states first...
Quercetin exerts anti-inflammatory, anti-oxidant and other protective effects. Previous studies have shown that senescent cells, such as fibroblasts type II airway epithelial are strongly implicated in the development of pulmonary fibrosis pathology. However, role macrophages during silicosis remains unclear. We investigated effects quercetin on macrophage senescence fibrosis, explored underlying mechanisms. Mice were randomized to six model groups. Vitro was also established by culturing...
Numerous studies have revealed that oxidative stress is closely associated with the occurrence and development of depression. Xiaoyao Pills (XYW) are included in Chinese Pharmacopoeia frequently used for treating anxiety depression by smoothing liver, strengthening spleen, nourishing blood. However, antidepressant effects XYW not yet been thoroughly investigated. The objective our study was to investigate antidepressant-like underlying molecular mechanism olfactory bulbectomized (OB) rat...
Liver injury is one of the common complications paraquat (PQ) poisoning, but whether degree liver related to patient prognosis still controversial. This study aimed investigate was a risk factor for death in PQ-poisoned patients.
To assess the occurrence of white coat adherence in families with children who have type 1 diabetes.Blood glucose data were downloaded from meters 72 children, aged 2-11 years, diabetes at four consecutive clinic visits. Generalized estimating equations used to analyze patterns blood monitoring (BGM) during 28 days before each visit.More frequent BGM was associated better glycemic control. Evidence a effect, frequency increasing visit, found only among low A1C levels.Highly motivated...
An animal model for HBV that more closely approximates the disease in humans is needed. The tree shrew (Tupaia belangeri) related to primates and susceptible HBV. We previously established neonatal shrews can be persistently infected with vivo, here present a six year follow-up histopathological study of these animals.Group A consists persistent infection, group B three suspected while C four free infection. Serum liver tissues samples were collected periodically from all animals. antigen...
AIM:To investigate the short-term and long-term efficacy of entecavir versus lamivudine in patients with spontaneous reactivation hepatitis B presenting as acute-on-chronic liver failure (ACLF). METHODS:This was a single center, prospective cohort study.Eligible, consecutive hospitalized received either 0.5 mg/d or 100 mg/d.All were given standard comprehensive internal medicine.The primary endpoint survival rate at day 60, secondary endpoints reduction virus (HBV) DNA alanine amino- BRIEF...
Purpose: This study aims to ascertain the relative outcomes in patients with hilar cholangiocarcinoma (HCCA) undergoing either unilateral or bilateral self-expanded metallic stent (SEMS) insertion. Materials and Methods: In this retrospective single-center study, 93 HCCA were treated through percutaneous insertion of SEMS during January 2012 December 2018. We compared technical success, clinical long-term treatment method. Results: Overall, 51 42 insertion, respectively, success rates 92.2%...
Objective: The traditional Chinese medicine (TCM) formulation Xiaoyao San (XYS) has a good clinical effect in treating ischemic stroke (IS). We explored the mechanism and material basis of XYS IS treatment. Methods: Network pharmacology was used to construct network components targets. R software analyze biological process pathway analysis targets In vitro, model apoptosis PC12 cells induced by oxygen-glucose deprivation/reperfusion (OGD/R) established evaluate neuroprotective its influence...
Pregnancy is a condition exhibiting increased susceptibility to oxidative stress, and Fe plays central role in generating harmful oxygen species. The objective of the present study investigate changes haematological status, stress erythrocyte membrane fluidity anaemic pregnant women after supplementation with without combined vitamins. was 2 months double-blind, randomised trial. Pregnant ( n 164) were allocated four groups: group C placebo control group; I supplemented daily 60 mg (ferrous...
Abstract Background Hepatitis B virus (HBV) infection continues to be an escalating global health problem. Feasible and effective animal models for HBV are the prerequisite developing novel therapies this disease. The tree shrew ( Tupaia ) is a small species evolutionary closely related humans, thus permissive certain human viral pathogens. Whether shrews could chronically infected with in vivo has been controversial decades. Most published research reported on adult shrews, only numbers of...