A5101490607- Paraquat toxicity studies and treatments
- Esophageal Cancer Research and Treatment
- Sarcoma Diagnosis and Treatment
- Anesthesia and Pain Management
- MRI in cancer diagnosis
- Fungal Biology and Applications
- Cardiac Imaging and Diagnostics
- Medicinal plant effects and applications
- Bone Tumor Diagnosis and Treatments
- Obsessive-Compulsive Spectrum Disorders
- Pancreatitis Pathology and Treatment
- Heme Oxygenase-1 and Carbon Monoxide
- Esophageal and GI Pathology
- Poisoning and overdose treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Drug-Induced Hepatotoxicity and Protection
- Gastric Cancer Management and Outcomes
- Functional Brain Connectivity Studies
- Pelvic and Acetabular Injuries
- Anesthesia and Sedative Agents
- Plant responses to water stress
- Pain Mechanisms and Treatments
- Neonatal Health and Biochemistry
- Liver Disease Diagnosis and Treatment
- Advanced MRI Techniques and Applications
North China University of Technology
2024-2025
First Affiliated Hospital of Zhengzhou University
2013-2024
Peking University
2023-2024
Peking University Third Hospital
2023-2024
Second Affiliated Hospital of Jilin University
2024
Qilu University of Technology
2024
Shandong Academy of Sciences
2024
Second Affiliated Hospital of Nanchang University
2022
Zhengzhou University
2022
Nanchang University
2022
The present study investigates whether paraquat (PQ) regulates polarization of alveolar macrophages through glycolysis and promotes the occurrence acute lung injury in rats. In vivo, PQ intraperitoneal injection was used to construct a model vitro, measured effect different concentrations on viability macrophages, explored metabolism at time points after intervention. Compared with normal control (NC) group, pathological damage rats increased gradually poisoning, reaching significant degree...
China, like many other countries around the world, faces a rapidly aging population. “Aging in place” is most popular choice for older people with more than 90% of urban living same residential areas they did middle age. Nighttime outdoor activity (NOA) among elderly and has positive impact on both their physical mental health. However, conditions nighttime places old gated communities often do not meet needs elderly, there are problems such as low lighting poor accessibility. This study...
Abstract Severe acute pancreatitis (SAP) is often associated with pulmonary inflammation leading to lung injury. Daphnetin, a natural coumarin derivative, has been reported exert anti-inflammatory effects. Here, we explored the effect and possible mechanism of daphnetin in mouse model SAP-associated injury induced by an intraperitoneal injection l -arginine. The severity pancreatic determined histology its score. Immunostaining inflammatory apoptotic cells was used demonstrate tissue...
Obsessive-compulsive disorder (OCD) is a chronic mental illness characterized by abnormal functional connectivity among distributed brain regions. Previous studies have primarily focused on undirected and rarely reported from network perspective.
Liver injury is one of the common complications paraquat (PQ) poisoning, but whether degree liver related to patient prognosis still controversial. This study aimed investigate was a risk factor for death in PQ-poisoned patients.
Epidemiological and clinical age differences in obsessive-compulsive disorder (OCD) have been reported symptoms morphometry changes; however, amplitude of low-frequency fluctuation the relationship between ALFF imaging has not thoroughly studied OCD. Age may be an important feature associated with distinct subtypes To examine effect on OCD, current study enrolled 92 OCD patients (32 pediatrics 60 adults) matched HCs (33 84 adults), undergoing resting-state functional magnetic resonance...
Abstract Objective Investigating the utility of serum exosomal markers CA125, HE4, and C5a, both individually in combination, for distinguishing between benign malignant ovarian tumors. Methods In this study, we selected a total 234 patients diagnosed with tumors, including 34 10 borderline 190 This study conducted comparisons levels C5a among distinct groups, as well making CA125 HE4. Furthermore, diagnostic performance was assessed through Receiver Operating Characteristic (ROC) curve...
Abstract To identify risk factors and develop a simple model to predict early prognosis of acute paraquat (PQ) poisoning patients, we performed retrospective cohort study PQ patients (n = 1199). Patients 913) with from 2011 2018 were randomly divided into training 609) test 304) samples. Another two independent cohorts used as validation samples for different time 207) site 79). Risk identified using logistic Markov Chain Monte Carlo (MCMC) simulation further evaluated latent class analysis....
This study was designed to determine the effects of polysaccharides from Cordyceps sinensis mycelium (CSP) on physical fatigue in mice. The mice were randomly divided into four groups (n = 16 each group), i.e. control group, low-dose CSP treated intermediate-dose group and high-dose group. received (100, 200 400 mg/kg, ig), drinking water ig. After 28 days, a forced swimming test performed some biochemical parameters related examined. present data suggested that could extend exhaustive time...
Abstract Background The present study aims to investigate the role of histogram analysis intravoxel incoherent motion (IVIM) in differential diagnosis benign and malignant breast lesions. Methods magnetic resonance imaging clinical data 55 patients (63 lesions) were retrospectively analyzed. multi-b-valued diffusion-weighted image was processed using MADC software obtain gray-scaled maps apparent diffusion coefficient (ADC)-slow, ADC-fast f. MaZda used extract metrics these maps. Combined...
Macrophage migration inhibitory factor (MIF) is an important pro-inflammatory cytokine implicated in sepsis, rheumatoid arthritis and other diseases. However, the role of MIF acute pancreatitis (AP) remains unclear. This study aims to explore pathogenesis AP using MIF−/− mice (referred as KO) biological effects pharmacological inhibition l-arginine induced AP. was C57BL/6 wild-type WT) KO by administration l-arginine. The severity assessed serum analysis amylase lipase, these cytokines TNF-α...
This study explored the role of metformin (MET) in regulating polarization alveolar macrophages to protect against acute lung injury (ALI) rats caused by paraquat (PQ) poisoning. The vivo studies showed that 35 mg/kg dose MET increased survival rate rats, alleviated pathological damages lungs and their systemic inflammation, promoted reduction pro-inflammatory factors interleukin-6 (IL-6) tumor necrosis factor-α (TNF-α) levels, anti-inflammatory factor IL-10 levels rat serum. At same time,...
Abstract Aim To evaluate individualized treatment strategy (ITS) and long‐term outcomes of endovascular Budd‐Chiari syndrome (BCS) with obstructed inferior vena cava (IVC) based on different degrees hepatic vein (HV) involvement. Methods From January 2006 to June 2017, 456 consecutive patients BCS IVC underwent ITS. All received recanalization. Then, 426 at least one patent HV no additional treatment. Twenty‐fivepatients membranous or segmental occlusion HVs recanalization for the remaining...
To describe our experience of reducing anastomotic leakage, a problem that has not been properly solved.
Objective To evaluate the effectiveness of intramedullary nailing for benign lesions proximal femur. Method A retrospective analysis was carried out on 68 cases in femur at our hospital from April 2002 to 2013 (38 men and 30 women). Mean age surgery 35.5 years (range, 22–56 years). The were divided into two groups: curettage lesion with bone grafting only as group (32 cases) internal fixation after removal (36 cases). For group, scraped out, deactivated washed thoroughly normal saline, then...
A kind of blood-repellent mist spray (MS) was proposed to prevent blood adhesion during surgery and played an important role in antibacterial wound-healing, which could be widely used the surface modification various medical gloves.
Objectives Initial precipitating injury (IPI) such as febrile convulsion and intracranial infection will increase the susceptibility to epilepsy. It is still unknown if functional deficits differ between mesial temporal lobe epilepsy with IPI (mTLE-IPI) without (mTLE-NO). Methods We recruited 25 mTLE-IPI patients, 35 mTLE-NO patients 33 healthy controls (HC). Static regional homogeneity (sReHo) dynamic (dReHo) were then adopted estimate alterations of local neuronal activity. One-way...