A5038745146- Influenza Virus Research Studies
- Paraquat toxicity studies and treatments
- Viral Infections and Vectors
- Respiratory viral infections research
- Mosquito-borne diseases and control
- Heme Oxygenase-1 and Carbon Monoxide
- Colorectal Cancer Surgical Treatments
- Animal Disease Management and Epidemiology
- Colorectal Cancer Screening and Detection
- Viral gastroenteritis research and epidemiology
- COVID-19 epidemiological studies
- Colorectal and Anal Carcinomas
- Poisoning and overdose treatments
- Gastric Cancer Management and Outcomes
- COVID-19 and Mental Health
- Climate Change and Health Impacts
- Genetic factors in colorectal cancer
- Hepatitis B Virus Studies
- Cancer-related molecular mechanisms research
- Microbial Community Ecology and Physiology
- Thermal Regulation in Medicine
- Viral Infections and Immunology Research
- Genomics and Phylogenetic Studies
- Misinformation and Its Impacts
- Gout, Hyperuricemia, Uric Acid
China Medical University
2015-2024
Guangzhou Center for Disease Control and Prevention
2009-2021
Guangzhou Chest Hospital
2020-2021
Central South University
2007-2020
Second Xiangya Hospital of Central South University
2007-2020
Guangzhou Medical University
2020
First Institute of Oceanography
2016
Qingdao National Laboratory for Marine Science and Technology
2016
Centers for Disease Control and Prevention
2009-2014
Chinese Academy of Sciences
2007-2013
Abstract Background Scrub typhus is becoming the most common vector born disease in Guangzhou, southern China. In this study, we aimed to examine effect of weather patterns on incidence subtropical city Guangzhou for period 2006–2012, and assist public health prevention control measures. Methods reported cases during 2006–2012 were obtained from National Notifiable Disease Report System (NNDRS). Simultaneous meteorological data including temperature, relative humidity, atmospheric pressure,...
Up-to-date information on the patterns of acute poisoning is crucial for proper management events. The objectives this study were to analyse characteristics patients suffering from admitted emergency department (ED) in a tertiary medical centre Northeast China and compare these with those previous comparable study.Retrospective descriptive study.Data collected hospital system Shengjing Hospital, China, January 2012 December 2016.All cases aged ≥11 years old diagnosis poisoning.In total, 5009...
Background Numerous urban villages (UVs) and frequent infectious disease outbreaks are major environmental public health concerns in highly urbanized regions, especially developing countries. However, the spatial quantitative associations between UVs infections remain little understood on a fine scale. Methodology principal findings In this study, relationships reported dengue fever (DF) epidemics during 2012–2017, gross domestic product (GDP), traffic system (road density, bus and/or subway...
The present study aims to investigate the impacts and mechanisms of silymarin on paraquat (PQ)-induced lung injury in vivo vitro. In experiments, a total 32 male Sprague-Dawley (SD) rats were randomly divided into four groups. killed day 3. Histopathological changes tissue examined using HE Masson's trichrome staining. Biomarkers neutrophil activation, pulmonary oedema, fibrosis, permeability oxidative stress detected. Several proinflammatory mediators antioxidant related proteins measured....
An orange-pigmented, Gram-negative, nonmotile, strictly aerobic and oxidase- catalase-positive bacterium (SM-A87(T)) was isolated from the deep-sea sediment of southern Okinawa Trough area. The main fatty acids were i15 : 0, i17 0 3OH, 1 G, omega 9c, 15 3OH summed feature 3 (comprising i-15 2OH and/or 16 7c). MK-6 predominant respiratory quinone. DNA G+C content 35.8 mol%. Flexirubin-type pigments absent. Phylogenetic analyses based on 16S rRNA gene sequences revealed that strain SM-A87(T)...
Background To evaluate the risk of recurrence and efficiency vaccination, we followed-up antibody responses in patients with 2009 pandemic H1N1 influenza persons who received vaccine Guangzhou China. Methods We collected serum samples from 129 86 vaccinated at day 0, 15, 30, 180 after disease onset or respectively. Antibody titers these were determined by haemagglutination inhibition (HI) assay using a local isolated virus strain A/Guangdong Liwan/SWL1538/2009(H1N1). Results HI positive rate...
We investigated the association between serum levels of glycated albumin (GA), hemoglobin (HbA1c ), and GA:HbA1c ratio presence diabetic nephropathy (DN) in patients with type 2 diabetes mellitus (T2DM).Two hundred six consecutive T2DM were enrolled from endocrinology ward at Shengjing Hospital China Medical University classified into groups: DN group (n = 71) non-diabetic (non-DN) 135).The showed significantly higher GA values compared non-DN group. After univariate logistic regression, GA,...
Influenza seriously affects the health of children, yet little evidence is available on association between meteorological factors and occurrence influenza among children in subtropical regions. The current study aimed to explore effects Guangzhou, a city China.The distributed lag nonlinear model (DLNM) was used assess China. Daily number cases aged 0-17 years from 2013 2017 were obtained National Information System for Disease Control Prevention.Mean temperature, relative humidity,...
Introduction: HPV vaccines were administered in mainland China from July 2017 at a gradual rate. We aimed to assess the vaccination rate and influencing factors among college students China.Methods: From October December 2018, we conducted face-to-face questionnaires including 5 sections 22 questions collect demographic information, infection transmission knowledge, vaccine knowledge attitudes Guangzhou, China. status cervical screening behaviors self-reported. Knowledge differences between...
Hand-foot-and-mouth disease (HFMD) is becoming one of the extremely common airborne and contact transmission diseases in Guangzhou, southern China, leading public health authorities to be concerned about its increased incidence. In this study, it was used an ecological study plus negative binomial regression identify epidemic status HFMD relationship with meteorological variables. During 2008-2012, a total 173,524 confirmed cases were reported, 12 death, yielding fatality rate 0.69 per...
Progressive pulmonary fibrosis is the most characteristic feature of subacute PQ poisoning. Epithelial-to-mesenchymal transition (EMT) reported to be involved in after exposure. Recent evidence suggested Notch signaling required for EMT. In this study, we investigated whether Notch1 and TGF-β1/Smad3 was EMT caused by PQ. It demonstrated that A549 cells underwent treated with at dose 300 μmol/L 6 days, charactered increasing expression mesenchymal marker α-SMA decreasing epithelial...
In the clinical setting, given potential adverse effects of thiazolidinediones and biguanides, we often have difficulty in treatment that no other insulin sensitizers are available for use type 2 diabetic mellitus (T2DM) patients. Tianmai Xiaoke Pian (TMXKP) is a traditional Chinese medicine tablet, which comprised chromium picolinate, Tianhuafen, Maidong, Wuweizi. To understand its mechanism action on resistance, TMXKP (50 mg/kg orally) was tested T2DM rats (induced by high-fat diet...
Phosphocreatine (PCr) is a natural compound, which can donate high-energy phosphate group to ADP synthesize ATP, even in the absence of oxygen and glucose. At present, it widely used cardiac renal ischemia-reperfusion (IR) disease. In this study, examine protective efficacy PCr against cerebral IR, disodium creatine was injected intravenously into rats before focal IR. Intracranial pressure (ICP), neurological score, infarction volume, apoptotic neurons were observed. Expression caspase-3...
Abstract To identify risk factors and develop a simple model to predict early prognosis of acute paraquat (PQ) poisoning patients, we performed retrospective cohort study PQ patients (n = 1199). Patients 913) with from 2011 2018 were randomly divided into training 609) test 304) samples. Another two independent cohorts used as validation samples for different time 207) site 79). Risk identified using logistic Markov Chain Monte Carlo (MCMC) simulation further evaluated latent class analysis....