A5100418044- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Cardiac Structural Anomalies and Repair
- Aortic aneurysm repair treatments
- Congenital Heart Disease Studies
- Cardiomyopathy and Myosin Studies
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Atrial Fibrillation Management and Outcomes
- Tissue Engineering and Regenerative Medicine
- Infective Endocarditis Diagnosis and Management
- Electrospun Nanofibers in Biomedical Applications
- Coronary Artery Anomalies
- Dialysis and Renal Disease Management
- Glioma Diagnosis and Treatment
- MicroRNA in disease regulation
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiac Arrhythmias and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer-related molecular mechanisms research
- Cardiovascular Function and Risk Factors
- Renal Diseases and Glomerulopathies
- Heart Failure Treatment and Management
- RNA Interference and Gene Delivery
- Viral Infections and Immunology Research
Zhongshan Hospital
2016-2025
Fudan University
2016-2025
The First Affiliated Hospital, Sun Yat-sen University
2016-2025
Sun Yat-sen University
2016-2025
Army Medical University
2021-2025
Southwest Hospital
2021-2025
Chinese PLA General Hospital
2009-2025
Qingdao University
2025
Qingdao Municipal Hospital
2025
Chi Mei Medical Center
2008-2024
Inorganic functionalization of metal-organic frameworks (MOFs), such as incorporation multiple inorganic building blocks with distinct metals into one structure and further modulation the metal charges, endows porous materials significant properties toward their applications in catalysis. In this work, by an exploration role 4-pyrazolecarboxylic acid (H2PyC) formation trinuclear copper pyrazolate a metalloligand situ, four new MOFs components order were constructed through one-pot synthesis....
Purpose The purpose of this paper is to examine the antecedents of, and relationships between, entrepreneurial opportunity recognition, individual‐level innovation performance. Design/methodology/approach Questionnaire data were collected from 268 senior R&D project team members (response rate 64.58 percent) along with 83 managers who evaluated their employees' innovative behaviors in one science park Taiwan. Findings results show that an individual's self‐efficacy, prior knowledge,...
The increasing prevalence of dyslipidemia has become a worldwide public health problem, and the varies widely according to socioeconomic, cultural ethnic characteristics. Chongqing experienced rapid economic development is now center Southwestern China. There are scant data on serum lipid profile residents in Chongqing, largest municipality directly under Central Government We conducted cross-sectional study representative sample 5375 aged ≥18 years, estimated its associated risk factors....
Purpose The purpose of this study was to examine the antecedent, perception external environment, and its relationship organizational learning, as well explore relationships between learning innovation performance at two levels, including individual organizational‐level performance. Design/methodology/approach Questionnaire data were collected from 268 senior R&D project team members who reported their about environment along with 83 managers evaluated employees' innovative behaviors....
Abstract Background Osteonecrosis of the femoral head (ONFH) is a common disabling disease with considerable social and economic impacts. Although extensive studies related to ONFH have been conducted in recent years, specific bibliometric analysis on this topic has not yet performed. Our study attempted summarize comprehensive knowledge map, development landscape, future directions research approach. Methods All publications concerning published from 2001 2020 were identified Web Science...
Background: Ultrasound-triggered sonodynamic therapy (SDT), as a non-invasive approach, has attracted considerable attention in wide variety of malignant tumors and other diseases. Over the past 2 decades, number scientific publications on SDT increased rapidly. However, there is still lack one comprehensive report that summarizes global research trends knowledge landscapes field detail. Thus, we performed bibliometric analysis from 2000 to 2021 track current hotspots highlight future...
Asymmetric hydrogenation of sterically hindered substrates still constitutes a long-standing challenge in the area asymmetric catalysis. Herein, an efficient palladium acetate (an inexpensive Pd salt with low toxicity) catalyzed N-tosylimines is realized high catalytic activities (S/C up to 5000) and excellent enantioselectivities (ee 99.9%). Quantum chemical calculations suggest that uniformly are observed due structurally different S- R-reaction pathways.
Background Central nervous system tumor (CNST) is one of the most complicated and lethal forms human tumors with very limited treatment options. In recent years, growing evidence indicates that oncolytic virotherapy (OVT) has emerged as a promising therapeutic strategy for CNSTs. And considerable amount literature on OVT-CNSTs been published. However, there are still no studies summarizing global research trends hotspots this field through bibliometric approach. To fulfill knowledge gap,...
The microRNA (mir)-374a has been implicated in several types of human cancer; however, its role diabetic nephropathy (DN) remains unclear. Monocyte chemoattractant protein (MCP)-1 is a chemokine that recruits macrophages to inflammatory sites and important for the development progression DN. However, relationship between miR-374a MCP-1 DN unknown. We addressed this present study by examining expression these factors kidney tissue samples from patients through loss- gain-of-function...
Abstract Introduction Gastric cancer is one of the common malignant tumors with a high incidence and mortality in China. Prognostic biomarkers potential predictors treatment efficacy gastric urgently need to be identified. Integrin‐β (ITGB) superfamily integrins involved cell adhesion, tissue repair, immune response, tumor metastasis. Methods We analyzed ITGB1 expression our hospital samples cohort. And public data The Cancer Genome Atlas stomach adenocarcinoma (TCGA‐STAD), Asian Research...
DLD is a key gene involved in "cuproptosis," but its roles tumor progression and immunity remain unclear. Exploring the potential mechanisms biological of may provide new insights for therapeutic strategies tumors. In present study, we analyzed role variety tumors by using several bioinformatic tools. The results showed that compared with normal tissues, tissues representing multiple cancers significant differential expression DLD. High was associated good prognosis BRCA, KICH, LUAD....
This study investigated the prevalence and determinants of hyperuricemia in Chinese type 2 diabetes mellitus (T2DM) patients with central obesity. A multicentric hospital-based cross-sectional was carried out Guangdong Province between August 2011 March 2012. At each hospital, T2DM obesity who were aged over 20 years, whose serum uric acid levels measured, had lived for >=1 year, recruited. Hyperuricemia defined as >420 μmol/L men >360 women. Binary logistic regression used to assess...
Background: Developmental dysplasia of the hip (DDH) is a common musculoskeletal disorder in newborns and also one most causes arthritis women. Many topics concerning DDH still remain controversial, global research trend this field has not been well-studied yet. The aim present study was to illustrate overall knowledge structure, development trends, hotspots DDH. Methods: publications related from 1998 2020 were identified Web Science Core Collection (WOSCC). Three bibliometric tools used...
Tumor recurrence and pseudoprogression (PsP) have similar imaging manifestations in conventional magnetic resonance (MRI), although the subsequent treatments are completely different. This study aimed to evaluate value of perfusion-weighted (PWI) differentiating PsP from glioma recurrence.A comprehensive literature search was performed clinical studies focused on recurrent using PWI, including dynamic susceptibility contrast MRI (DSC-MRI), enhanced (DCE-MRI), arterial spin labeling (ASL)....
Alzheimer's disease (AD)-like cognitive impairment, a kind of Neuro-COVID syndrome, is reported complication SARS-CoV-2 infection. However, the specific mechanisms remain largely unknown. Here, we integrated single-nucleus RNA-sequencing data to explore potential shared genes and pathways that may lead dysfunction in AD COVID-19. We also constructed ingenuity AD-high-risk scores based on from transcriptomic, proteomic, Genome-Wide Association Studies (GWAS) identify disease-associated cell...
BACKGROUND Serum retinol-binding protein (RBP) is the primary transport of circulating vitamin A. RBP has a crucial role in maintaining nutrient metabolism and physiologic homeostasis. Several studies have indicated that serum participates progression diabetes diabetes-related complications. However, impact on lower limb atherosclerosis not been determined individuals with type 2 mellitus (T2DM). AIM To determine association between T2DM. METHODS This retrospective study enrolled 4428...