A5101405348- Sarcoma Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Bone Tumor Diagnosis and Treatments
- Spinal Fractures and Fixation Techniques
- Advanced Malware Detection Techniques
- Pelvic and Acetabular Injuries
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Security and Verification in Computing
- Cancer Immunotherapy and Biomarkers
- Cancer Cells and Metastasis
- Neonatal Health and Biochemistry
- Clinical Nutrition and Gastroenterology
- Physiological and biochemical adaptations
- Musculoskeletal synovial abnormalities and treatments
- Cancer Research and Treatments
- Surgical site infection prevention
- COVID-19 and healthcare impacts
- Bone health and treatments
- Thyroid Disorders and Treatments
- Traditional Chinese Medicine Analysis
- RNA Research and Splicing
- Reconstructive Surgery and Microvascular Techniques
- Plant nutrient uptake and metabolism
Tianjin Medical University Cancer Institute and Hospital
2023-2025
Chengdu Third People's Hospital
2023-2024
Shanghai Ocean University
2024
Southwest Jiaotong University
2024
First Affiliated Hospital of Zhengzhou University
2013-2023
National Yang Ming Chiao Tung University
2023
Taipei Veterans General Hospital
2023
Johnson University
2023
Rutgers, The State University of New Jersey
2023
Liaoning University
2023
Abstract Background Triple‐negative breast cancer (TNBC) is a highly heterogeneous and clinically aggressive disease. Accumulating evidence indicates that tertiary lymphoid structures (TLSs) tumor budding (TB) are significantly correlated with the outcomes of patients who have TNBC, but no integrated TLS‐TB profile has been established to predict their survival. The objective this study was investigate relationship between TLS/TB ratio clinical TNBC using artificial intelligence (AI)‐based...
Acinic cell carcinoma (AciCC) of the breast is an exceptionally rare subtype invasive carcinoma, often exhibiting a triple-negative phenotype and relatively indolent behavior. Since first case reported by Roncaroli colleagues in 1996, no more than 60 additional cases have been described English medical journals, usually as reports or small series. In this study, we presented in-depth analysis 14 AciCC breast, including 4 pure AciCCs 10 mixed with other histologic types. We clinicopathologic...
Microwave ablation has been used to treat bone tumors in extremities for more than 30 years. With improved recognition, updated microwave equipment, and expanded clinical application, recently widely tumors. To standardize the application of treatment limbs, research results experience involving use limbs have summarized, a guideline designed. This is aimed at providing reliable basis indications, preoperative evaluation decision‐making, perioperative treatment, complications, other issues...
Background Breast abscess is developed on the basis of acute mastitis, which will cause damage to physical and mental health lactating women an important factor affecting rate breastfeeding. This study examined risk factors for mastitis develop into breast abscess, analyzed distribution pathogenic bacteria, bacterial resistance, treatment outcome. Methods The medical records 316 cases 219 were retrospectively collected. We compared differences drug resistance. Univariate analysis binary...
Recently exposed vulnerabilities reveal that branch predictors shared by different processes leave the attackers with opportunities for malicious training and perception. Instead of flush-based or physical isolation hardware resources, we want to achieve content in these tables some lightweight processing using randomization as follows. (1) Content encoding. We propose use hardware-based thread-private random numbers encode contents predictor tables. It achieves a similar effect logical but...
Objective To explore the clinical efficacy and complications of treating sternal tumors by resection titanium mesh thoracic reconstruction. Methods This retrospective analysis eight patients with treated in D epartment O rthopedic S urgery at F irst A ffiliated H ospital Z hengzhou U niversity from J anuary 2008 to une 2012 included five men three women aged 37–66 years (mean, 50.4 years). The histological diagnoses were chondrosarcoma (two cases), osteosarcoma (one), malignant fibrous...
Lethal hemorrhage could endanger lives. Although many hemostatic agents are commercially available with good clinical effect, it is necessary to develop novel materials high efficacy, biological safety, low cost, easily preparation and excellent biodegradability biocompatibility. Here, biodegradable uniform microspheres regular spherical architecture porous microstructure were prepared by thermosensitive carboxymethyl chitin (CMCH) substitution degree deacetylation through...
Ammonium is one of the prevalent nitrogen sources for growth and development higher plants. acquisition from soil facilitated by ammonium transporters (AMTs), which are plasma membrane proteins that exclusively transport ammonium/ammonia. However, functional characteristics molecular mechanisms AMTs in apple remain unclear. In this work, 15 putative AMT genes were identified classified into four clusters (AMT1–AMT4) apple. According to expression analysis, these had varying expressions...
The purpose of this study is to establish the prognosis osteosarcoma patients based on characteristics immune-related gene pairs. We used lasso Cox regression model construct and verify signature consisting 14 This can accurately predict overall survival an independent prognostic factor for patients. For we constructed a signature-based nomogram. results nomogram show that our bring clinical net benefits. then assessed abundance infiltrating immune cells in each sample, combine set...
Light beams carrying orbital-angular-momentum (OAM) play an important role in optical manipulation and communication owing to their unbounded state space. However, it is still challenging efficiently discriminate OAM modes with large topological charges thus only a small part of the states have been usually used. Here we demonstrate that neural networks can be trained sort unknown superpositions. Using intensity images generalized simulations experiments as input data, illustrate our network...
We aimed to provide a new typing method for osteosarcoma (OS) based on single-cell RNA sequencing (scRNA-seq) and bulk RNA-seq data from the perspective of lipid metabolism examine its potential mechanisms in onset progression OS.Scores six metabolic pathways were calculated by single-sample gene set enrichment analysis (ssGSEA) scRNA-seq dataset three microarray expression profiles. Subsequently, cluster was conducted using unsupervised consistency clustering. Furthermore, clustering...
Metastatic papillary thyroid carcinoma in the lymph nodes with no primary tumor gland is rarely reported and easily missed. We report case of a 27-year-old female who presented tiny nodule her left gland, which was detected during routine ultrasonographic examination. She did not present fever, weight loss, or night sweats, palpable mass found physical The preoperative blood routine, function, thyroglobulin test results were normal. Needle aspiration cytology recommended. However, patient...
WWOX (WW domain-containing oxidoreductase) is known to be an important tumor suppressor in cancer. In this study, we used samples from 201 osteosarcoma patients investigate the effects of on angiogenesis and invasion. levels were negatively correlated with RUNX2 VEGF levels, but not OPN levels. Among clinicopathological characteristics examined, was associated only response neoadjuvant chemotherapy, its expression tissues a predictor disease-free survival. promoted apoptosis inhibited...
Abstract Acute myeloid leukemia (AML) is a cancer of hematopoietic stem cells with rapid progression. The progression AML can be regulated by estrogenic signals. Our present data showed that an industrial endocrine‐disrupting chemical, bisphenol A (BPA), promote the proliferation and decrease their sensitivity to daunorubicin cytarabine treatment. Among tested cytokines, BPA treatment expression interleukin‐4 (IL‐4) while increasing IL‐6. Overexpression IL‐4 or neutralization antibody IL‐6...
Osteosarcoma (OS) is the most prevalent human bone malignancy, and presents a global annual morbidity of approximately five cases per million. Notably, precise efficient targeted therapy has become promising strategy for treatment OS; however, there still an urgent need identification suitable therapeutic targets. Metastasis-associated in colon cancer 1 (MACC1) was first identified tumors by differential display RT-PCR, shown to be involved regulation tumor growth metastasis through...
Abstract Indirubin is widely used as the active component of “Dangui Luhui Wan” in ancient China. However, its effects against osteosarcoma (OS), most common primary malignancy, are still unknown. In our present study, we investigated Indirubin‐3′‐monoxime (I3M), a derivative indirubin with better water solubility, OS cells. We found I3M inhibited cell proliferation dose‐dependent manner. Flow cytometry assays showed that could not only induce apoptosis time‐ and manner but also regulate...