A5043089416- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Medical Imaging and Analysis
- Cervical and Thoracic Myelopathy
- Infectious Diseases and Tuberculosis
- Orthopedic Infections and Treatments
- Orthopaedic implants and arthroplasty
- Musculoskeletal pain and rehabilitation
- Anesthesia and Pain Management
- Scoliosis diagnosis and treatment
- Bone Tissue Engineering Materials
- Osteoarthritis Treatment and Mechanisms
- Diagnosis and treatment of tuberculosis
- Management of metastatic bone disease
- Pelvic and Acetabular Injuries
- Titanium Alloys Microstructure and Properties
- Spinal Hematomas and Complications
- Gold and Silver Nanoparticles Synthesis and Applications
- Nerve Injury and Rehabilitation
- Hematological disorders and diagnostics
- Tissue Engineering and Regenerative Medicine
- Advanced Drug Delivery Systems
- Cancer, Hypoxia, and Metabolism
- Shoulder and Clavicle Injuries
- 3D Printing in Biomedical Research
Nanfang Hospital
2007-2024
Southern Medical University
2008-2024
421 Hospital of PLA
2010
Abstract This study investigates therapeutic efficacy of photothermal therapy (PTT) in an orthotropic xenograft model bone metastasis breast cancer. The near-infrared (NIR) irradiation on Multi-Walled Carbon Nanotubes (MWNTs) resulted a rapid heat generation which increased with the MWNTs concentration up to 100 μg/ml. alone exhibited no toxicity, but inclusion dramatically decreased cell viability when combined laser irradiation. Thermographic observation revealed that treatment 10 μg...
To improve osseointegration caused by the stress-shielding effect and inert nature of titanium-based alloys, in this work, we successfully constructed a strontium calcium phosphate (Sr-CaP) coating on three-dimensional (3D)-printed Ti6Al4V scaffolds to address issue. The energy-dispersive X-ray spectroscopy (EDS) diffraction (XRD) results indicated that coatings with without Sr doping mainly consisted CaHPO4. bonding strength met required ISO 13 779-4-2018 standard (≥15 MPa). vitro suggested...
A clinical follow-up study was performed to evaluate lumbar disc nucleus replacement clinically and functionally. The objective assess the efficacy of prosthetic (PDN) for treatment herniation. PDN designed treat patients suffering from herniation and/or degeneration. Clinical trials were first conducted in 1996, results showed that device effective most who implanted. These studies had been carried out with implanted a pair devices. main complication migration. Therefore, based on single...
The screw and cement technique is a convenient method used to rebuild medial tibial plateau defects in primary total knee arthroplasty (TKA). objective of this study was perform finite element assessment determine the effect different numbers screws on stability TKA whether differences exist between two insertion angles.Six models with filled one model only were generated. Contact stresses surface cancellous bone areas calculated.Compared cement-only technique, stress border decreased by 10%...
Objective Surgical site infection (SSI) after spinal surgery is still a persistent worldwide health concern as it worrying and devastating complication. The number of samples in previous studies limited the role conservative antibiotic therapy has not been established. This study aims to evaluate clinical efficacy feasibility empirical treatment for suspected early‐onset deep SSI. Methods We conducted retrospective identify all cases with SSI lumbar instrumented between January 2009 December...
Objective: To assess long‐term clinical results of prosthetic disc nucleus (PDN) replacement for the treatment lumbar herniation. Methods: Seventy‐two patients with herniation were implanted a single PDN device from March 2002 to December 2003. Fifty‐eight (80.6%) attended clinical, functional, and radiographic follow‐up examinations more than 48 months. Independent analysis was performed by careful review interviews, operative reports, preoperative postoperative radiographs, computed...
Zinc and its alloys are considered to be next-generation materials for fabricating absorbable biomedical devices. However, cytotoxicity has been reported associated with rapid degradation. To address these issues, a composite coating (PLA/Li-OCP) consisting of CaHPO4 conversion (Ca-P) polylactic acid (PLA) decorated Li-octacalcium phosphate particles was constructed on pure zinc. The immersion tests showed that the presence Ca-P PLA/Li-OCP zinc could reduce pH value. Compared coating,...
The aim of this study was to evaluate the effect lumbar sacralization on level vertebral slip and disc degeneration in patients with L4 spondylolysis.
Objective This study aimed to investigate the strength of a novel micro‐dynamic pedicle screw by comparing it traditional screw. Methods Forty‐five lumbar vertebrae received on one side and other as follows (traditional group vs group): 15 underwent instant pull‐out testing; 5000‐cyclic fatigue loading 10,000‐cyclic testing micro‐computed tomography (micro‐CT) scanning. The peek force normalized after testing, were recorded estimate resistance two types screws. Bone mineral density was...
OBJECTIVE To investigate the long-term efficacy of anterior approach surgery on cervical spondylotic myelopathy and factors affecting prognosis. METHODS The data in 116 patients suffered from spondylosis January 1992 to December 2000 were reviewed, including 80 male cases 36 female cases, whose age ranged 76 years (mean, 51 years). preoperative course disease was 2 months 20 19 months). There 65 (56.0%) with single segments involved, 44 (37.9%) two segments, 7 (6.0%) three segments....
Anterior transdiscal axial screw (ATAS) fixation is an alternative or supplement to the plate and constructs for upper cervical spine injury. However, no existing literatures clarified anatomic feasibility of this technique subaxial spine. Therefore, objective study was evaluate anatomical establish guidelines use ATAS Fifty normal spines had radiographs determine proposed trajectory (the length insertion angle) interbody graft-related parameters disc height depth, distance between anterior...