A5042719775- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Cervical and Thoracic Myelopathy
- Pelvic and Acetabular Injuries
- Medical Imaging and Analysis
- Hip and Femur Fractures
- Scoliosis diagnosis and treatment
- Management of metastatic bone disease
- Spinal Dysraphism and Malformations
- Orthopedic Surgery and Rehabilitation
- Bone health and osteoporosis research
- Neurosurgical Procedures and Complications
- Peripheral Nerve Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Head and Neck Surgical Oncology
- Cerebrospinal fluid and hydrocephalus
- Meningioma and schwannoma management
- Autophagy in Disease and Therapy
- Musculoskeletal pain and rehabilitation
- Shoulder Injury and Treatment
- Bone and Joint Diseases
- Ophthalmology and Visual Impairment Studies
- Spinal Cord Injury Research
- Histone Deacetylase Inhibitors Research
- Nasolacrimal Duct Obstruction Treatments
Southern Medical University
2015-2024
Nanfang Hospital
2015-2024
Wuhan University
2024
Guangdong Academy of Medical Sciences
2023
Guangdong Provincial People's Hospital
2023
Chinese PLA General Hospital
2023
Yuncheng University
2022
First Affiliated Hospital of Soochow University
2019-2020
Soochow University
2019-2020
National Natural Science Foundation of China
2015-2019
The ketone metabolite β-hydroxybutyrate (βOHB), is reported to be neuroprotective after spinal cord injury (SCI) in rats, but the underlying mechanism remains unknown. present study aims investigate effects of βOHB on suppression oxidative stress and inhibition class I histone deacetylases (HDACs) vivo vitro models. Rats were fed with ketogenic diet (KD) or standard (SD) for 3 weeks. A C5 hemi-contusion was applied these animals 14th day experiment, samples harvested 1st, 3rd 7th days SCI,...
Objective . To investigate the change of spinopelvic sagittal balance and clinical outcomes after posterior lumbar interbody fusion (PLIF) in patients with degenerative spondylolisthesis (DS), especially relationship between parameters persistent low back pain (PLBP). Methods 107 who were diagnosed DS underwent PLIF our department enrolled retrospectively present study. Sagittal including lordosis (LL), segmental (SL), height disc (HOD), sacral slope (SS), pelvic incidence (PI), tilt (PT)...
Protecting white matter is one of the key treatment strategies for spinal cord injury (SCI), including alleviation myelin loss and promotion remyelination. Rapamycin has been shown neuroprotective effects against SCI cardiotoxic while enhancing autophagy. However, specific neuroprotection rapamycin after cervical not reported. Therefore, we aim to evaluate role in hemi-contusion mice. Forty-six 8-week-old mice were randomly assigned into group ( n = 16), vehicle sham 10). All groups received...
A biomechanical human cadaveric study.The aim of this study was to measure L2-L3 facet joint contact forces in a flexibility test using thin film electroresistive sensors, and orientation on computed tomographic (CT) scan images, examine the effects lumbar forces.Biomechanically, bilateral joints play critical role maintaining stability spine. The effect remains unknown.Eight spine specimens (L2-L3) were tested by applying pure moment ±7.5 Nm three directions loading (flexion-extension,...
Occipitalization of atlas (OA) is a congenital disease with the possibility anomalous bony anatomies and C2 pedicle screw insertion technically challenging. However, there are no existing literatures clarified dimensions angulations pedicles, lamina lateral masses for in patients OA. Therefore, aim this study was to assess morphometric features placement OA guide use surgical screws. Measurements on computer tomography (CT) images including angle, length thickness, mass thickness axis...
Treatment of carpal tunnel syndrome (CTS) remains a challenge for hand surgeons. Carpal release (CTR) using nasal instruments has the advantages both endoscopy and open surgery. In this study we aimed to explore effectiveness CTR in Chinese patients. We present case series 49 cases idiopathic CTS treated with mini-incision technique instruments. The average recovery days before return normal work complications were recorded. mean grip strength, pinch sensation evaluated. Subjective results...
A computed tomography-based morphometric measurement of the pediatric craniovertebral junction for clival screw placement.To identify differences clivus at different ages and establish guidelines fixation.Anterior fixation junction, a viable alternative to posterior occipital-cervical fixation, requires placement. The morphology may be associated with greater difficulty in adequate purchase because spheno-occipital synchondrosis (clival fissure).Morphometric analysis was conducted on...
Abstract Clival screw and plate fixation technique is an alternative or supplement to the occipitocervical instrumentation. However, no report has clarified applied anatomy of clivus in patients with atlas assimilation (C1A), especially for clival fixation. Therefore, we measured parameters lengths, widths, putative clival-cervical angel foramen magnum diameters on CT images a cohort 81 C1A without C1A. The showed rectangular shape 96.3% (78/81) normal-like triangle 3.7% (3/81) patients....
Study Design. Retrospective study. Objective. To evaluate the feasibility of C2 pedicle screw fixation with “in-out-in” technique in patients basilar invagination (BI). Summary Background Data. The is a which enters vertebrae through parapedicle. has been used upper cervical spine fixation. However, anatomic parameters associated application this BI are unclear. Materials and Methods. We measured width (PW), distance between vertebral artery (VA) transverse foramen (VATF), safe zone, limit...
Study Design. A retrospective analysis of collected data. Objective. Our study aims to present the morphology cranial-cervical spinal canal in basilar invagination (BI) patients. Summary Background Data. BI is characterized by protrusion odontoid process into foramen magnum (C0), leading compression cervicomedullary junction. However, no has ever clarified anatomical diameters patients with BI. Methods. The retrospectively examined computed tomography (CT)-based characteristics a cohort 84...
Study Design. Retrospective analysis of collected data and operative experiment on human cadavers. Objective. To describe a novel technique the anterior atlantooccipital (AC) transarticular screw fixation, to analyze pertinent anatomy with cadaveric radiographic assessment feasibility, safety, general applicability this technique. Summary Background Data. In some situations, posterior AC fixation techniques may not be possible, or require supplemental which include congenital hypoplasia,...
The vertebral endplate (VEP) was damaged after spinal instability induced by cervical muscle section (CMS). Whether CMS induces bone formation and mechanical loading change in the vertebra is still obscure. This study aimed to explore damage CMS. Forty-eight rats were randomly divided into group sham group. C6/7 segments harvested at 4, 8, 12 weeks surgery. microarchitectures of C6 and lesions intervertebral disc height measured micro-computed tomography. Micro-finite element analysis used...