A5115589201- Acute Ischemic Stroke Management
- Insect-Plant Interactions and Control
- RNA modifications and cancer
- Cerebrovascular and Carotid Artery Diseases
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Plant Parasitism and Resistance
- Coronary Artery Anomalies
- Bladder and Urothelial Cancer Treatments
- Advancements in Battery Materials
- Kawasaki Disease and Coronary Complications
- Stroke Rehabilitation and Recovery
- Cancer Immunotherapy and Biomarkers
- Cardiac, Anesthesia and Surgical Outcomes
- Venous Thromboembolism Diagnosis and Management
- Hernia repair and management
- Insect symbiosis and bacterial influences
- Circular RNAs in diseases
- Advanced Nanomaterials in Catalysis
- Epigenetics and DNA Methylation
- Advanced Battery Materials and Technologies
- Nematode management and characterization studies
- Esophageal and GI Pathology
- FOXO transcription factor regulation
- Liver Disease Diagnosis and Treatment
Hunan Agricultural University
2025
Third Hospital of Hebei Medical University
2024-2025
Hebei Medical University
2019-2025
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2025
Hainan University
2025
Henan Normal University
2022-2025
Army Medical University
2023-2025
Qingdao University of Science and Technology
2025
Wuhan University of Technology
2025
Xinqiao Hospital
2023-2025
Abstract Existing surgical tissue adhesives on the market cannot meet desired demand for clinical operations due to their limited adhesivity or undesired cytotoxicity. A new bioadhesive is derived from skin secretion of Andrias davidianus (SSAD). This bioinspired SSAD has significantly stronger adhesion than fibrin glue and improved elasticity biocompatibility when compared cyanoacrylate both ex vivo in vivo. Additionally, SSAD‐based adhesive decreases wound healing time promotes...
A Mott–Schottky electrocatalyst composed of amorphous Co–B nanochain embedded in CoO x nanosheets was developed for highly efficient conversion NO 3 − -to-NH .
The poor compatibility of carbonate-based electrolytes with lithium metal anodes results in unstable solid electrolyte interphase, leading to dendrite formation, low Coulombic efficiency, and short cycle life. To address this issue, we propose a novel fluorinated that leverages bis(fluorosulfonyl)imide (LiFSI), along solvents. An extremely concentration nitrate exerts substantial impact on the Li ion solvation structure, inducing an anions-rich inorganic-rich interphase layer mainly composed...
Importance Persisting or new thrombi in the distal arteries and microcirculation have been reported to limit benefits of successful endovascular thrombectomy for patients with acute ischemic stroke. It remains uncertain whether intra-arterial thrombolysis by urokinase following near-complete complete reperfusion improves outcomes among stroke due large vessel occlusion. Objective To assess efficacy adverse events after Design, Setting, Participants This investigator-initiated, randomized,...
Plant basic leucine zipper (bZIP) transcription factors are one of the largest and most diverse gene families play key roles in regulating stress processes. Brachypodium distachyon is emerging as a widely recognized model plant for temperate grass family herbaceous energy crops, however there no comprehensive analysis bZIPs B. distachyon, especially those involved tolerances.In this study, 96 bZIP genes (BdbZIPs) were identified distributing unevenly on each chromosome them scattered low CpG...
Summary Aphids secrete diverse repertoires of salivary effectors into host plant cells to promote infestation by modulating defence. The greenbug Schizaphis graminum is an important cereal aphid worldwide. However, the secreted S. are still uncharacterized. Here, 76 proteins were identified from watery saliva using transcriptome and proteome analyses. Among them, a putative effector Sg2204 was significantly up‐regulated during feeding stages, transient overexpression in Nicotiana benthamiana...
Metastasis is a crucial aspect of disease progression leading to death in patients with prostate cancer (PCa). However, its mechanism remains unclear. We aimed explore the lymph node metastasis (LNM) by analyzing heterogeneity tumor microenvironment (TME) PCa using scRNA-seq. A total 32,766 cells were obtained from four tissue samples for scRNA-seq, annotated, and grouped. InferCNV, GSVA, DEG functional enrichment analysis, trajectory intercellular network evaluation, transcription factor...
Aphid salivary proteins are critical in modulating plant defence responses. Grain aphid Sitobion miscanthi is an important wheat pest worldwide. However, the molecular basis for regulation of resistance to cereal aphids remains largely unknown. Here, we show that SmCSP4, a chemosensory protein from S. saliva, secreted into plants during feeding. Delivery SmCSP4 leaves activates salicylic acid (SA)-mediated responses and subsequently reduces performance by deterring feeding behaviour. In...
Abstract Lithium metal batteries (LMBs) are considered as one type of the most promising next‐generation energy storage devices with high‐energy‐density, and stabilizing lithium anodes (LMAs) to overcome LMBs’ safety concerns performance degradation has attracted extensive attention. Introducing advanced polymer materials into critical components LMBs proven be an effective approach for LMAs toward practical application LMBs. In addressing lack a timely review on emerging progress in LMAs,...
Abstract The pulse widths of fast radio bursts are always broadened due to the scattering plasma medium through which electromagnetic wave passes. recorded width will be further affected by telescopes since sampling time and bandwidth cannot infinitely small. In this study, we focus on at least 3287 detected from FRB 20121102A as 2023 October. Various effects such broadening, redshift-induced instrumental broadening examined. At a redshift 0.193, is factor approximately 0.16 cosmological...
Covalent attachment of polymers to cells and tissues could be used solve a variety problems associated with cellular therapies. Insulin-dependent diabetes mellitus is disease resulting from the autoimmune destruction beta islets Langerhans in pancreas. Transplantation into diabetic patients an attractive form treatment, provided that protected host's immune system prevent graft rejection, smaller numbers transplanted volumes sufficient reverse diabetes. Therefore, need exists develop islet...
Background/Aims: The aim of this study is to investigate the clinicopathological and prognostic values miR-149 expression its roles in colorectal cancer (CRC) progression. Methods: qRT-PCR was performed detect CRC cell lines or tissues. Also, clinical significance investigated. further explored whether inhibits migration invasion cells by targeting mammalian Forkhead Box M1 (FOXM1). Results: significantly downregulated tissues, low observed be correlated with lymph node distant metastasis...
Background/Aims: Previously, we have shown that microRNA (miR)-149 suppresses the migration and invasion of colorectal cancer (CRC) cells by targeting forkhead box transcription factor (FOXM1). However, roles miR-149 in chemoresistance CRC to 5-Fluorouracil (5-FU) is unclear. The aim this study investigate whether targets FOXM1 regulate 5-FU resistance CRC. Methods: qRT-PCR assay was performed detect expression 5-FU-resistant (HCT-8/5-FU LoVo/5-FU) their parental (HCT-8 LoVo). Also, effects...
// Tao Xie 1, * , Jian Geng Ye Wang 1 Liya 2 Mengxi Huang Jing Chen Kai Zhang Lijun Xue Xiaobei Liu Mao Yanan Qian Tingting Dai Lili Ren Hongju Yu Rui Longbang Cheng Xiaoyuan Chu Department of Medical Oncology, Jinling Hospital, Nanjing Clinical School Southern University, 210002, China Medicine, These authors have contributed equally to this work Correspondence to: Chu, email: chuxiaoyuan000@163.com Chen, chencheng1289@126.com Keywords: colorectal cancer, FOXM1, 5-FU, chemoresistance...
Aphid salivary effectors play important roles in modulating plant defense responses. The grain aphid Sitobion miscanthi is one of the most economically cereal aphids worldwide. However, little information available on identification and functional analysis S. miscanthi. In this study, a candidate effector Sm9723 was identified, which specifically expressed glands highly induced during feeding phase. Transient overexpression Nicotiana benthamiana suppressed BAX INF1-induced cell death....
Nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic without specific FDA-approved drugs. Recent advances suggest that chromatin remodeling and epigenetic alteration contribute to development of NAFLD. The functions corresponding molecular modulator in NAFLD, however, are still elusive. KDM1A, commonly known as LSD1 (lysine-specific histone demethylase 1), has been reported increase glucose uptake hepatocellular carcinoma. In addition, a recent study suggests inhibition...
Due to the low toxicity, biocompatibility and eco-friendliness, microorganisms have received a lot of attention for gold nanoparticles (AuNPs) synthesis. This work isolated fungal strain capable efficiently generating AuNPs from aerobic granular sludge, named XY3. Comparison 18S rDNA sequence results showed that fungus XY3 belongs Candida rugopelliculosa. were synthesized by initiating an Au3+-induced stress response prompted reduction Au3+ Au0 It is worth noting addition nutritional...
Two-dimensional (2D) Janus semiconductor materials have shown significant potential in the fields of electronics and optoelectronics. The problem interface contact with electrodes is still faced preparation 2D devices based on them. In this work, we study interfacial properties M2OS (M = Ga, In) material graphene by using ab initio density functional calculations. results show that an n-type quasi-Ohmic (Ohmic contact) formed regardless whether electrode O or S surface Ga2OS (In2OS)....