A5102995889- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Total Knee Arthroplasty Outcomes
- Dysphagia Assessment and Management
- Osteoarthritis Treatment and Mechanisms
- Bone fractures and treatments
- Hip and Femur Fractures
- Neurological Disease Mechanisms and Treatments
- Inflammatory mediators and NSAID effects
- Voice and Speech Disorders
- Orthopedic Surgery and Rehabilitation
- Elbow and Forearm Trauma Treatment
- Liver Disease Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Anesthesia and Pain Management
- Natural product bioactivities and synthesis
- Acute Ischemic Stroke Management
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Economic and Environmental Valuation
- Shoulder Injury and Treatment
- Cervical and Thoracic Myelopathy
- Biotin and Related Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Fluoride Effects and Removal
First Affiliated Hospital of Fujian Medical University
2025
Fujian Medical University
2025
Wenzhou Medical University
2024
Wenzhou Central Hospital
2024
Hangzhou Hospital of Traditional Chinese Medicine
2014-2023
Nanjing University of Chinese Medicine
2019-2023
Longyan University
2019-2022
Nanjing University
2019-2021
First Hospital of Shijiazhuang
2021
Southern Medical University
2020
Importance: Acute ischemic stroke patients due to intracranial internal carotid artery (ICA) occlusion often have poor functional outcomes despite endovascular treatment (EVT). Objective: To investigate the efficacy and safety of intravenous methylprednisolone as adjunct EVT for with ICA occlusion. Design, Setting, Participants: This was a post-hoc analysis MARVEL randomized, double blind, placebo-controlled clinical trial conducted from February 2022 June 2023 at 82 centers across China....
As a degenerative joint disease, osteoarthritis (OA) constitutes major cause of disability that seriously affects the quality life large population people worldwide. However, effective treatment can successfully reverse OA progression is lacking until now. The present study aimed to determine whether two small non-coding RNAs miR-29a and miR-140, which are significantly downregulated in OA, be applied together as potential therapeutic targets for treatment. MiRNA synergy score was used...
The screw and cement technique is a convenient method used to rebuild medial tibial plateau defects in primary total knee arthroplasty (TKA). objective of this study was perform finite element assessment determine the effect different numbers screws on stability TKA whether differences exist between two insertion angles.Six models with filled one model only were generated. Contact stresses surface cancellous bone areas calculated.Compared cement-only technique, stress border decreased by 10%...
Purpose: Infected nonunion after open reduction internal fixation (ORIF) is a serious complication. The aim of this study was to evaluate the usefulness serum D-dimer for preoperative diagnosis infected nonunion. Patients and methods: undergoing debridement external (n=32) replacement due aseptic failure (n=34) were enrolled compared in retrospective study. optimum cutoff value identification determined by calculating Youden J statistic. sensitivity, specificity, positive predictive (PPV),...
MiR-20a has been reported as a key regulator to pro-inflammatory factor release in fibroblast-like synoviocytes (FLS), which caused rheumatoid arthritis (RA). However, the molecular mechanism of miR-20a RA remains be further elucidated. This study aimed investigate roles pathology. (n = 24) and osteoarthritis (OA, n 20) normal healthy tissues 16) were collected from operation. TargetScan dual-luciferase reporter performed predict confirm potential binding sites on ADAM metallopeptidase...
Osteoarthritis (OA) has a high incidence rate in the elderly population and is cause of chronic degenerative joint disease. Current therapeutic approaches to OA are effective but come with some side effects. Therefore, it urgent find new safe treatments. This study aimed clarify function taraxasterol (TAX) isolated from Taraxacum officinale papain-induced rat model. We observed that TAX alleviated typical OA-caused phenomena joint. The expression serum inflammatory mediators such as TNF-α,...
Authors of this study aimed to investigate the efficacy and safety endovascular treatment (EVT) versus standard medical (SMT) alone in patients with acute basilar artery occlusion (BAO) moderate deficit (National Institutes Health Stroke Scale [NIHSS] score 10-19).
The aim of this study was to detect the severity ulnar variance (UV) compared with contralateral hand on postoperative wrist function in patients distal radius fracture. 116 cases unilateral fracture were retrospectively analyzed and divided into high or low UV groups (Dividing value = 2.5 mm). following parameters used evaluate effect: palmar tilt, radial inclination, VAS score, DASH score function. existed widely, accounting for 93.1% (108 cases). correlated grip strength, (P < 0.05)....
<h3>Introduction</h3> Chronic exposure to combined fluoride and arsenic continue be a major public health problem worldwide. Although there have been reports in the literature about toxicity of individually, is very little known effects these two elements. In this study, based on population <i>in vivo</i>, aim explore bone fluorine provides scientific basis for mechanism, prevention control endemic fluorine-arsenic poisoning toxicity. <h3>Methods</h3> The population-based study group was...
Purpose To investigate willingness to pay for cataract surgery, and its associations, in Northwestern China.Methods Four hundred thirty-eight persons aged 50 years above, diagnosed with indicated identified an outreach screening program were included. Subjects offered a willingness-to-pay interview the maximal amount that subjects would be willing surgery. Age, gender, literacy, education level, occupation, annual household income recorded.Results Among 328 (74.9%) who completed interview,...
To study the complications and efficacy of self-made, antibiotic-loaded cement articulating spacers in treatment infected hip replacement.Between January 2006 July 2016, 265 patients (266 hips) received a spacer as part two-stage protocol. Among those patients, there were 143 males(144 122 females(122 hips). The with vancomycin two Steinman pins made by self-made mold system. Meanwhile, another antibiotic was added to according drug sensitivity test. Record if prosthesis removed, related...
To investigate the clinical change of post-stroke dysphagia after intervention Liyan Tongqiao （relieving sore-throat and dredging orifices）acupuncture using cranial diffusion tensor imaging (DTI).A total 60 patients with were enrolled randomly divided into acupuncture group neurology treatment group, 30 in each group. The given routine swallowing rehabilitation training, those received at Sishencong (EX-HN1), Baihui (GV20), bilateral Tai-yang (EX-HN5), Fengchi (GB20) tongue triple...