A5100748945- Anesthesia and Neurotoxicity Research
- Intensive Care Unit Cognitive Disorders
- Neonatal and fetal brain pathology
- Anesthesia and Sedative Agents
- Cardiac Ischemia and Reperfusion
- Traditional Chinese Medicine Analysis
- Neurological Disease Mechanisms and Treatments
- Neuroscience and Neuropharmacology Research
- Lipid metabolism and disorders
- S100 Proteins and Annexins
- Liver Disease Diagnosis and Treatment
- Cancer, Stress, Anesthesia, and Immune Response
- Healthcare and Venom Research
- Endometrial and Cervical Cancer Treatments
- Prenatal Screening and Diagnostics
- Chronic Kidney Disease and Diabetes
- Pneumonia and Respiratory Infections
- Bone health and osteoporosis research
- Thyroid Disorders and Treatments
- Boron Compounds in Chemistry
- Berberine and alkaloids research
- Silymarin and Mushroom Poisoning
- Pain Mechanisms and Treatments
- Tea Polyphenols and Effects
- Circular RNAs in diseases
Tang Du Hospital
2024-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2003-2025
Guang’anmen Hospital
2021-2025
Nanjing Medical University
2008-2024
Air Force Medical University
2020-2024
Affiliated Hospital of Southwest Medical University
2018-2024
Wuhan Union Hospital
2024
Central Hospital of Zibo
2024
Guangxi Medical University
2023
Creative Commons
2023
Abstract Background and Aim Remimazolam tosilate (RT) is a new short‐acting GABA(A) receptor agonist, having potential to be an effective option for procedural sedation. Here, we aimed compare the efficacy safety of RT with propofol in patients undergoing upper gastrointestinal endoscopy. Methods This positive‐controlled, non‐inferiority, phase III trial recruited at 17 centers, between September 2017 November 2017. A total 384 scheduled undergo endoscopy were randomly assigned receive or...
Prolonged exposure to volatile anesthetics, such as isoflurane and sevoflurane, causes neurodegeneration in the developing animal brains. Recent studies showed that dexmedetomidine, a selective α2-adrenergic agonist, reduced isoflurane-induced cognitive impairment neuroapoptosis. However, mechanisms for effect are not completely clear. Thus, we investigated whether or sevoflurane at an equivalent dose anesthesia during brain development different degrees of neuroapoptosis this is by...
Background Delayed neurocognitive recovery after surgery is associated with poor outcome. Most surgeries require general anesthesia, of which sevoflurane and propofol are the most commonly used inhalational intravenous anesthetics. The authors tested primary hypothesis that patients laparoscopic abdominal under propofol-based anesthesia have a lower incidence delayed than sevoflurane-based anesthesia. A second there were blood biomarkers for predicting to occur. Methods randomized,...
The notion that diabetic nephropathy is the leading cause of renal fibrosis prompted us to investigate effects blood glucose fluctuation (BGF) under high condition on kidney in mice. and BGF animal models were established this study. Immunohistochemistry, Western blot, RT-PCR analysis applied detect expression type I collagen, matrix metalloproteinase-1 (MMP1), metalloproteinase inhibitor 1 (TIMP1), transforming growth factor beta (TGF- β 1), phosphorylated-ERK, p38, smad2/3, Akt. treatment...
Scope Sleep deprivation (SD) negatively affects all aspects of health, with one serious consequence being impaired cognition. Farnesol (FOL) is a sesquiterpene synthesized by plants and mammals that has antioxidant, anti‐inflammatory, neuroprotective properties. This study investigates the mechanism underlying effect FOL on SD‐induced cognitive impairment. Methods results Administration dramatically ameliorates chronic sleep (CSD)‐induced In addition, notably attenuates oxidative stress...
Background Atherosclerosis is a widely studied pathophysiological foundation of cardiovascular diseases. Inflammation and dyslipidemia are risk factors that promote the formation atherosclerotic plaques. The gut microbiota their metabolites considered independent for atherosclerosis. Polydatin combined with hawthorn flavonoids, as extracts Polygonum cuspidatum Sieb. et Zucc . Crataegus pinnatifida Bunge , have shown excellent protective effects. However, underlying mechanism requires further...
Objectives: To explore the effect of lavender essential oil olfactory stimulation as a non-pharmacological pain management strategy in preterm infants during radial artery blood collection. Methods: The 96 from neonatal intensive care unit (NICU) tertiary hospital China were randomly divided into two groups: control group (n = 47) and intervention 49). In group, conventional skin contact soothing measures given before collection, while was implemented addition to measures, i.e., cotton swab...
This edited volume endeavours to apply the robust theoretical framework dialogical self theory (DST) in different educational contexts. The 13 contributors either integrated DST their research p...
In Brief BACKGROUND: Isoflurane, a commonly used inhaled anesthetic, induces apoptosis in rat pheochromocytoma neurosecretory cells (PC12) concentration- and time-dependent manner via an as yet unknown mechanism. We hypothesize that isoflurane by causing abnormal calcium release from the endoplasmic reticulum (ER) activation of inositol 1,4,5-trisphosphate (IP3) receptors. A presenilin-1 (PS1) mutation associated with familial Alzheimer’s disease was shown to increase activity IP3 receptors,...