A5100660592- Advanced Sensor and Energy Harvesting Materials
- Fluid Dynamics and Turbulent Flows
- Nanoplatforms for cancer theranostics
- Fluid Dynamics and Vibration Analysis
- Conducting polymers and applications
- Tactile and Sensory Interactions
- Wind and Air Flow Studies
- Trace Elements in Health
- Nanofabrication and Lithography Techniques
- Prion Diseases and Protein Misfolding
- Heat Transfer Mechanisms
- Nanoparticle-Based Drug Delivery
- Cancer, Stress, Anesthesia, and Immune Response
- Nonlinear Dynamics and Pattern Formation
- ZnO doping and properties
- Pharmaceutical Economics and Policy
- Photodynamic Therapy Research Studies
- Sirtuins and Resveratrol in Medicine
- Computational Fluid Dynamics and Aerodynamics
- Anodic Oxide Films and Nanostructures
- Alzheimer's disease research and treatments
- Muscle activation and electromyography studies
- Adipose Tissue and Metabolism
- Immune cells in cancer
- Electoral Systems and Political Participation
Kunming University
2024-2025
Shandong First Medical University
2025
Beijing Institute of Nanoenergy and Nanosystems
2022-2024
Chinese Academy of Sciences
2007-2024
Guangxi University
2021-2024
National University of Singapore
2024
Huazhong University of Science and Technology
2020-2023
Soochow University
2019-2023
Hunan University
2022-2023
Hunan University of Finance and Economics
2023
Abstract Despite the promise of sonodynamic processes in cancer therapy, existing sonosensitizers often fail to regulate generation reactive oxygen species (ROS) against tumors, potentially leading off‐target toxicity normal tissues. We report a transformable core‐shell nanosonosensitizer (TiO 2 @CaP) that reinvigorates ROS and dissolves its CaP shell release Ca 2+ an acidic tumor microenvironment (TME) under ultrasound activation. Thus, TiO @CaP acts as smart specifically induces...
Virtual reality is a brand-new technology that can be applied extensively. To realize virtual reality, certain types of human-computer interaction equipment are necessary. Existing technologies often rely on cameras, data gloves, game pads, and other equipment. These either bulky, inconvenient to carry use, or expensive popularize. Therefore, the development convenient low-cost high-precision device contribute positively technology. In this study, gesture recognition wristband full keyboard...
The protein deacetylase, sirtuin 1 (SIRT1), involved in regulating hepatic insulin sensitivity, shows circadian oscillation and regulates the clock. Recent studies show that misalignment leads to resistance (IR); however, underlying mechanisms are largely unknown. Here, we CLOCK brain muscle ARNT-like (BMAL1), two core transcription factors, correlated with sensitivity. Knockdown of or BMAL1 induces IR, whereas their ectopic expression attenuates IR. Moreover, change sensitivity is impaired...
The Yangtze River Economic Belt is the most important manufacturing economic belt in China. level of green innovation efficiency directly affects overall competitiveness China’s industry. With panel data from 11 provinces and cities along China for period 2008 to 2017, this paper applies slacks-based measure (SBM)-data envelopment analysis (DEA) model Tobit conduct an empirical study effects government research development subsidies environmental regulations on industry Belt. results show...
Hydrogel-based epidermal electrodes attract widespread attention in health monitoring and human-machine interfaces for their good biocompatibility, skin-matched Young's modulus, stable situ electrophysiological recording performance. However, it is difficult to make the exact conformal attachment between skin because of hair, wrinkles, as well complex, curved contours skin. This also results signal distortion large noise. Here, a body temperature enhanced skin-adhesive electrode proposed...
Certain anaerobic microbes with the capability to colonize tumor microenvironment tend express heterologous gene in a sustainable manner, which will inevitably compromise therapeutic efficacy and induce off-tumor toxicity vivo. To improve precision controllability of bacteria-based therapeutics, Escherichia coli Nissle 1917 (EcN), engineered sense blue light release encoded flagellin B (flaB), is conjugated lanthanide upconversion nanoparticles (UCNPs) for near-infrared (NIR)...
Circadian misalignment induces insulin resistance in both human and animal models, skeletal muscle is the largest organ response to insulin. However, how circadian clock regulates sensitivity underlying molecular mechanisms are still largely unknown. Here we show locomotor output cycles kaput (CLOCK) brain aryl hydrocarbon receptor nuclear translocator-like protein (BMAL)-1, two core transcription factors, down-regulated insulin-resistant C2C12 myotubes mouse muscle. Furthermore, signaling...
Abstract Artificial intelligence‐enhanced skin‐like sensors based on flexible nanogenerators have been widely used in physiological signal acquisition, artificial organ, sensory simulation, human movement status recognition, and other biomedical related fields due to their excellent biocompatibility, comfortable wearing experience, high sensing accuracy, low power consumption. In this paper, the working principle, evolution process, several established general strategies of are summarized...
Rationale: Immune checkpoint (ICP) blockade therapy combined with chemotherapy is a promising treatment strategy for tumors. Chemotherapeutic agents usually function inside the tumor cells, while ICP inhibitors are efficacious out of cells. It desirable to effectively co-deliver an inhibitor and agent different sites tumor. We have designed effective drug delivery system accomplish both objectives. Methods: Pickering nanoemulsion (PNE) using multi-sensitive nanogels pH-responsive,...
Wearable exoskeletons are developing rapidly due to their superiority in improving human ability and efficiency. The construction of a multifunctional exoskeleton system relies on an efficient continuous energy supply various high-performance sensors. Here, magnetic-driven piezoelectric cantilever generator (MPCG) array is designed for harvesting angle sensing joint motions. Combining theoretical derivation experimental characterization, it found that the nonlinear magnetic force acting...
The fourth-generation semiconductor material, gallium oxide (Ga2O3) has received extensive attention for its wide bandgap, ultra-high breakdown electric field, high temperature resistance, and better radiation resistance. Ga2O3 nanomaterials are primarily synthesized through the thermal treatment of oxyhydroxide (GaOOH), but synthesis methods GaOOH depend on complex reaction process, pressure, precision equipment other conditions, resulting applicability is significantly limited. Herein, a...
Histone methylation is an important epigenetic mechanism that plays essential role in regulating gene expression mammalian cells. To understand its influence on inflammation, of H3K4, H3K9, H3K36, H3K79, and H4K20, the most common histones methylated inflammatory response was analyzed murine RAW264.7 cells bone marrow-derived macrophages (BMDMs) upon lipopolysaccharide (LPS) stimulation. LPS stimulation resulted enhanced at H3K4 H3K9 both BMDMs. further confirm whether LPS-stimulated H3K4me2...
Regenerative braking system is a promising technology for electrical vehicles, in which the excess kinetic energy can be effectively collected and utilized. As new based on contact electrification, triboelectric nanogenerator (TENG) suitable harvesting dissipated systems. Herein, dual mode rotary TENG (DMR‐TENG) reported, installed bicycle disc brake collecting riding mode. First, electric generation mechanism of DMR‐TENG analyzed then characteristics different structural kinematic...
Abstract Coronavirus disease 2019 (COVID‐19) patients may experience persistent impairment of the lungs after recovery and discharge, which can cause a decline in pulmonary function. Therefore, regular function tests are essential for COVID‐19 recovered patients, portable, home‐based test devices great significance during pandemic. Herein, portable self‐powered turbine spirometer (PSTS) is designed respiratory flow measurement assessment with high accuracy, humidity resistance, good...
Peptides and proteins possess an inherent propensity to self-assemble into generic fibrillar nanostructures known as amyloid fibrils, some of which are involved in medical conditions such Alzheimer disease. In certain cases, structures can self-propagate living systems prions transmit characteristic traits the host organism. The mechanisms that allow species but not others function fully understood. Much progress understanding prion phenomenon has been achieved through study yeast this...