A5047589937- Nanoplatforms for cancer theranostics
- Photodynamic Therapy Research Studies
- Tissue Engineering and Regenerative Medicine
- Cancer-related Molecular Pathways
- Advanced biosensing and bioanalysis techniques
- Photochromic and Fluorescence Chemistry
- Electrospun Nanofibers in Biomedical Applications
- Cancer Research and Treatments
- Analytical Chemistry and Sensors
- Cardiac Valve Diseases and Treatments
- Microfluidic and Capillary Electrophoresis Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- 2D Materials and Applications
- Retinoids in leukemia and cellular processes
- Advanced Memory and Neural Computing
- Neural Networks and Reservoir Computing
- 3D Printing in Biomedical Research
- RNA Interference and Gene Delivery
Wuhan National Laboratory for Optoelectronics
2022-2024
Huazhong University of Science and Technology
2022-2024
Certain anaerobic microbes with the capability to colonize tumor microenvironment tend express heterologous gene in a sustainable manner, which will inevitably compromise therapeutic efficacy and induce off-tumor toxicity vivo. To improve precision controllability of bacteria-based therapeutics, Escherichia coli Nissle 1917 (EcN), engineered sense blue light release encoded flagellin B (flaB), is conjugated lanthanide upconversion nanoparticles (UCNPs) for near-infrared (NIR)...
Abstract A recently developed synthetic retinoid abrogates proliferation and induces apoptosis of drug‐resistant malignant‐cancer‐stem‐cell‐like cells. However, the underlying mechanisms how cancer‐stem‐cell‐like cell tumor‐repopulating (TRC) are elusive. Here, it is shown that although conventional anticancer drugs cisplatin, all‐trans retinoic acid, tazarotene all inhibit cytoskeletal tension decondense chromatin prior to inducing TRC apoptosis, half‐maximal inhibitory concentration...
Discs and numerous other consumer products have been developed for point of care testing (POCT) to replace traditional large expensive biochemical devices in certain scenarios. Herein, we propose a drip-dry strategy (2D strategy) assisted Blu-ray disc (BD) biosensor, termed BDB, rapid portable POCT within 30 min with the cost single test < $1. The platform utilizes covered area formed by deposition substance be measured on activated BD surface after evaporation water realizes quantitative...
Systemically administered drugs can often lead to off-target delivery, inducing compromised therapy efficacy and significant toxic side effects. We hypothesize that increasing drug targeting improving spatiotemporally drug-controlled release enhance the anti-tumor effects reduce of chemotherapy drugs. To achieve this goal, 9-aminocamptothecin (ACPT), a drug, is conjugated with lanthanide-doped upconversion nanoparticles (UCNPs) via photolabile linker camouflaged melittin-functionalized 4T1...
Abstract Nonlinear optical phenomena (NLOPs) in two-dimensional (2D) materials can be envisioned for neuromorphic functions at the device and related system level. But it has been attended rarely that transition among multi-energy states as one origin of NLOPs directly used functions, which is assisted to understand nature device-level nonlinear performance. Here we introduced a pump-probe-control technology reveal multi-energy-state multilayer molybdenum disulfide, enhancing signals by...