A5105978555- Vestibular and auditory disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Sinusitis and nasal conditions
- Ear Surgery and Otitis Media
- Asthma and respiratory diseases
- Nasal Surgery and Airway Studies
- Allergic Rhinitis and Sensitization
- Ophthalmology and Eye Disorders
- Hearing Loss and Rehabilitation
- Neuroscience of respiration and sleep
- Cerebral Venous Sinus Thrombosis
- Neonatal and fetal brain pathology
- Otitis Media and Relapsing Polychondritis
- Respiratory and Cough-Related Research
- Glaucoma and retinal disorders
- Biochemical Analysis and Sensing Techniques
- Neonatal Health and Biochemistry
- Head and Neck Surgical Oncology
- Viral-associated cancers and disorders
- Lymphoma Diagnosis and Treatment
- Noise Effects and Management
- Olfactory and Sensory Function Studies
- Laser Applications in Dentistry and Medicine
- Ocular Surface and Contact Lens
- Sarcoidosis and Beryllium Toxicity Research
Başkent University
2012-2024
Lokman Hekim Üniversitesi
2023-2024
Başkent University Hospital
2016-2023
Turkish Thoracic Society
2013-2016
Ankara University
2009
To investigate the association between nasal polyposis (NP) and single nucleotide polymorphisms of proinflammatory cytokines IL (interleukin) 1alpha (the IL1A gene), IL-1beta IL1B tumor necrosis factor alpha TNFA gene).Prospective case-control trial.Tertiary referral center.Eighty-two patients with NP 106 healthy volunteers without sinonasal disease.Genotypes (4845G, 4845T), (-511C, -511T) (-238G, -238A -308G, -308A) were identified by restriction fragment length polymorphism analyses after...
The identities and frequencies of MYO15A mutations associated with hearing loss in different populations remained largely unknown. We screened the gene for 104 unrelated multiplex consanguineous Turkish families autosomal recessive nonsyndromic sensorineural using autozygosity mapping. screening 10 mapped to DFNB3 locus revealed five previously unreported mutations: p.Y289X (1 family), p.V1400M p.S1481P p.R1937TfsX10 (3 families), p.S3335AfsX121 (2 families). Recurrent were conserved...
Background Although patients with nasal polyposis frequently exhibit concomitant allergy, there is limited information about the impact of allergy on severity polyposis. The goal this study was to evaluate role in Methods Polyp sizes, computed tomography (CT) scores, skin-prick test results, blood total eosinophil count, serum levels immunoglobulin E, symptom and recurrences were analyzed 83 results compared between allergic nonallergic Results No association found presence per testing polyp...
Ankylosing spondylitis (AS) is a rheumatic disease characterized by chronic inflammation. The aim of this study was to evaluate the functions cochlea and vestibular system in patients with AS. group consisted 32 AS 30 healthy volunteers as control group. Otorhinolaryngologic examinations were performed all together pure-tone audiometry, speech tests, impedancemetry, transient evoked otoacoustic emission (TEOAE) electronystagmography (ENG). A significant difference found between 2 groups...
Using Affymetrix 10K arrays, we searched for regions of homozygosity in 51 Turkish families including at least three members with either congenital or prelingual autosomal recessive non‐syndromic sensorineural hearing loss (ARNSSNHL), and identified four whose deafness mapped to the DFNB6 locus on 3p21 containing TMIE gene. Mutation analysis revealed p.R84W mutation all families. Screening this 254 ARNSSNHL, without GJB2 mutations, additional affected A novel was found a non‐complementary...
Background Expression of matrix metalloproteinase (MMP)-9 increases in nasal polyp tissues. However, the impact MMP-9 genotypes on development polyposis (NP) is unknown. The aim this study was to examine a potential association promoter gene polymorphism with NP. Methods A prospective and case–control performed 93 patients NP 115 controls without sinonasal disease. Genotypes (–1562C>T) were identified by restriction fragment length analyses after polymerase chain reaction. Results...
A disintegrin and metalloproteinase (ADAM)-33 is a member of matrix metalloproteinases. This protein takes role in angiogenesis airway remodeling asthma. Because histopathological findings asthma nasal polyposis (NP) are similar, the aim this study was to evaluate ADAM-33 expression NP.Immunohistochemical staining specimens 47 patients with NP 8 concha bullosa performed detect ADAM-33. Paraffin blocks were used identify polyclonal antibodies. Immunostaining epithelial cells, stroma,...
The aim of this study was to evaluate the effect combined hearing and tinnitus masking devices that are appropriately programmed for acoustic stimulations using wide-band noise over specific frequency range tinnitus.A total 21 patients were randomly divided into 2 groups. Group I (12 patients) managed with betahistine dihydrochloride (2HCl) fitted either a aid or sound generator, group II (9 treated 2HCl 3 months. Audiological tests, pitch matching determine tinnitus, an assessment severity,...
The pure-tone audiometry results following glycerol administration indicated a positive effect on cochlear endolymphatic hydrops. Glycerol cervical vestibular-evoked myogenic potential (cVEMP) tests are useful means of diagnosing saccular There was no correlation between cVEMP and audiological results.To document the changes in hearing outcomes cVEMPs patients with Ménière's disease (MD) 10 healthy volunteers before after oral glycerol.Twenty-nine study group subjects were chosen complaints...
Background: The concept of occupational self-esteem is the value judgment developed towards chosen profession, while job satisfaction includes positive emotional attitudes job. Professional and levels audiologists are a matter curiosity. Purpose: To determine effect workplace types in Turkey on their professional levels. Study sample: study included 307 working various workplace. Participation was voluntary. Data Collection: A Personal Information Form, Arıcak’s Occupational Self-Esteem...
Schwannomas are uncommon benign tumors of the external auditory canal. The clinical features, differential diagnosis, and surgical treatment these lesions discussed. A 51-year-old patient presented with a mass obliterating meatus. Excisional biopsy was performed. Diagnosis reported to be schwannoma by histopathologic examination. Schwannoma, rarely seen in canal, can managed precise excision tumor via transmeatal approach.
The aim of this study was to assess the demographic findings and surgical results patients who underwent submandibular gland excision at a tertiary care center.The clinical characteristics histopathological 45 had undergone between 1997 2014 were evaluated in detail.Twenty-eight (62.2%) 17 (37.8%) presented with complaint painful mass painless mass, respectively. Histopathologic investigation specimens revealed sialolithiasis 14 (31.1%), chronic sialadenitis 16 (35.6%), benign tumor 12...
The goal of this study was to determine whether there an association between perinatal risk factors prematurity and vestibular evoked myogenic potentials (VEMPs). A prospective case-control trial designed. Fifty preterm newborns (100 ears) with a gestational age <37 weeks were included. control group consisted 20 healthy term infants (40 ears). VEMP recordings performed, mean latencies p13 calculated in all subjects. Multivariable logistic regression used investigate the influence...
Many physiological changes occur during pregnancy. The aim of the study was to reveal whether there is a change in middle ear resonance frequency A prospective case-control designed at tertiary referral center. included 46 pregnant women third trimester (27-40 weeks) and 43 nonpregnant voluntary women. All subjects underwent pure-tone audiometry multifrequency tympanometry. Pure-tone hearing levels frequencies 250 8000 Hz values were compared between Impact age, side tested ear, weight...