A5078133001- Blood groups and transfusion
- Renal Transplantation Outcomes and Treatments
- Erythrocyte Function and Pathophysiology
- Transplantation: Methods and Outcomes
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cytomegalovirus and herpesvirus research
- Blood transfusion and management
- Parvovirus B19 Infection Studies
- Hemoglobinopathies and Related Disorders
- Blood donation and transfusion practices
- Organ Donation and Transplantation
- Ovarian cancer diagnosis and treatment
- Organ Transplantation Techniques and Outcomes
- Clinical Laboratory Practices and Quality Control
- Hepatitis B Virus Studies
- Complement system in diseases
- Polyomavirus and related diseases
- Viral Infections and Vectors
- Pelvic and Acetabular Injuries
- Lymphoma Diagnosis and Treatment
- T-cell and B-cell Immunology
- Artificial Intelligence in Healthcare and Education
- Immune Cell Function and Interaction
- SARS-CoV-2 and COVID-19 Research
- Herpesvirus Infections and Treatments
Pusan National University
2013-2024
Pusan National University Hospital
2015-2024
Pusan National University Yangsan Hospital
2018-2019
Busan Medical Center
2019
Yang Hospital
2014
Keimyung University
2004
Konkuk University
2004
Kyung-Hwa Shin, M.D., In-Suk Kim, Hyun Ji Lee, Hyung-Hoi Chulhun L. Chang, Young Mi Hong, Ki Tae Yoon, and Mong Cho, M.D.. Ann Lab Med 2017;37:204-12. https://doi.org/10.3343/alm.2017.37.3.204
Tumor markers are useful for detection and preoperative evaluation of ovarian tumors. We evaluated the clinical usefulness cancer antigen (CA) 125, human epididymis 4 (HE4), CA72-4 levels Risk Ovarian Malignancy Algorithm (ROMA) values differential diagnosis malignant borderline tumors among suspected tumors, effects endometriosis on these tumor markers.In a total 266 patients (213, 14, 39 with benign, respectively), CA125, HE4, were measured, ROMA calculated. Medians each marker compared...
We aimed to assess the temporal trends of incident syphilis and its associated risk factors among men with HIV (Human Immunodeficiency Virus) in Korea during COVID-19 pandemic. conducted a retrospective cohort study attending an clinic between 2005 2022. Of 767 HIV, 499 were included contributed 3220 person-years (PY) observation period. Eighty-two patients diagnosed syphilis, overall incidence 2.55/100 PY (95% confidence interval [CI] 20.56–31.53). The per 100 gradually decreased from 2.43...
Despite the advantages of extracorporeal membrane oxygenation (ECMO), secondary catheter infection remains a major concern during ECMO support. In this study, to clarify mechanism catheter-related infection, we evaluated impact on biofilm formation surfaces catheters, and investigated clinical factors associated with formation. Catheters used for were prospectively collected aseptically from femoral vein, internal jugular artery 81 patients acute cardiorespiratory failure between January...
Abstract Objectives Few studies have reported on delta checks for tumour markers, even though these markers are often evaluated serially. Therefore, this study aimed to establish a practical check limit in different clinical settings five markers: alpha-fetoprotein, cancer antigen 19-9, 125, carcinoembryonic antigen, and prostate-specific antigen. Methods Pairs of patients’ results (current previous) between 2020 2021 were retrospectively collected from three university hospitals. The data...
This study compared the estimated costs and times required for ABO/Rh(D) typing unexpected antibody screening using an automated system manual methods.The total cost included direct labor costs. Labor were calculated on basis of average operator salaries unit values (minutes), which was hands-on time to test one sample. To estimate values, workflows recorded video, each process analyzed separately.The method 5.65 8.1 min during regular unsocial working hours, respectively. The value less...
Many mathematical models have been developed to describe the lateral dynamics of a moving web, including Shelton's model. Experimental results in this study showed that existing model does not fully characteristic for some typical operating conditions. An experimental was derived by means system identification using well-known least-square method improve prediction capability dynamics. A commercial guidance usually has proportional and integral control structure. Sometimes it may eliminate...
Abstract Objectives Misidentification errors in tumor marker tests can lead to serious diagnostic and treatment errors. This study aims develop a method for detecting these using machine learning (ML)-based delta check approach, overcoming limitations of conventional methods. Methods We analyzed five test results: alpha-fetoprotein (AFP), cancer antigen 19-9 (CA19-9), 125 (CA125), carcinoembryonic (CEA), prostate-specific (PSA). A total 246,261 records were used the analysis. Of these,...
Thalassemia is highly prevalent in Southeast Asia but rare Korea; however, Asian immigrant population recently rising Korea. We investigated the prevalence of thalassemia Korea context increasing immigration.This prospective, observational, multicenter study was conducted between September 2015 and August 2017. A total 669 subjects <30 years living were grouped into multiethnic (N=314) Korean (N=355) groups. Hb electrophoresis complete blood count (CBC) performed. If low mean corpuscular...
This study aimed to determine practical delta check limits (DCLs) for thyroid function tests (TFTs) detect sample misidentifications across various clinical settings. Between 2020 and 2022, 610,437 paired TFT results were collected from six university hospitals. The absolute DCL (absDCL) was determined using the 95th percentile each setting a random 60 % of total data. These absDCLs then tested within different settings remaining 40 data, alongside mix-up datasets result comparisons....
Abstract Background In clinical laboratories, the precision and sensitivity of autoverification technologies are crucial for ensuring reliable diagnostics. Conventional methods have limited applicability, making error detection challenging reducing laboratory efficiency. This study introduces a machine learning (ML)-based technology to enhance tumor marker test detection. Methods The effectiveness various ML models was evaluated by analyzing large data set 397 751 model training internal...
Frequencies of red blood cell (RBC) group antigens differ by ethnicity. Since the number immigrants is increasing in Korea, RBC should be assessed children/youths with parents different ethnicities to ensure safe transfusions. We investigated frequency antigens, except for ABO and RhD, 382 children youths having Korean non-Korean ethnicities. Subjects were divided into those ethnically (Korean group; N=252) at least one parent ethnicity (non-Korean N=130). The 37 genotyped using ID CORE XT...
In viral meningitis, proinflammatory cytokines were detected at higher levels in the cerebrospinal fluid (CSF) and might play an important role inflammatory process. Our goal was to compare cytokine profiles CSF of children enteroviral meningitis (EVM) with versus without pleocytosis. total, 158 patients enrolled this prospective cohort study classified as EVM (group-A, n = 101), nonenteroviral aseptic (group-B, 27), control (group-C, 30) groups. Of 101 EVM, 71 had pleocytosis (group-A1) 30...
Endothelial cells are vital in the transplant immune system as semiprofessional antigen-presenting cells. Few studies have investigated importance of anti-endothelin subtype A receptor (ETAR) antibodies kidney transplantation. Here, we aimed to analyze association between anti-angiotensin II type I (AT1R) and anti-ETAR presence anti-endothelial risk allograft rejection transplantation.In total, 252 patients who underwent transplantation were enrolled this study. Antibodies for human...
Bortezomib has significant activity in treating multiple myeloma (MM). The risk of herpes zoster (HZ) been reported to increase significantly with bortezomib treatment, but the predisposing factors for HZ are not clear. This study is a retrospective analysis relevant Korean MM patients treated bortezomib.Sixty-six refractory or relapsed who underwent chemotherapy were included study. Prophylactic antiviral drugs used treatment. following parameters reviewed: age, gender, stage and type MM,...
In Korea, there were issues regarding the use of immunoassays for anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies to detect infection. So, we compared antibody results eight kinds commercial using clinical remnant specimens.We several immunoassay kits tested on 40 serum samples from 15 confirmed patients and 86 laboratory. Eight IVD kits-four enzyme-linked immunosorbent assay, two lateral flow rapid immunochromatographic assays, chemiluminescent with one RUO kit...
The novel HLA‐A*30:01:25 allele differs from HLA‐A*30:01:01:01 by a single nucleotide substitution located within exon 2, codon 1.
Hyperbilirubinemia, which is a sign of hemolytic disease the newborn (HDN), can irreversibly damage central nervous system. To determine etiology HDN in affected patients and characterize changing pattern bilirubin using direct antiglobulin testing (DAT). We collected clinical data from newborns who underwent perinatal DAT their mothers, between August 2008 July 2017. Among 303 neonates, 37 (12.2%) showed positive results. The predictive values (PPVs) negative (NPVs) based on results were...
<b><i>Introduction:</i></b> The effects of lymphocyte subtypes, including helper (Th), natural killer (NK), and regulatory (Treg) cells, other T-cell subtypes on treatment outcomes in diffuse large B-cell lymphoma (DLBCL) patients are not clearly established. <b><i>Methods:</i></b> Among 151 consecutive diagnosed with DLBCL, we collected peripheral blood samples at diagnosis from 91 who received least 1 cycle R-CHOP (cyclophosphamide,...
Coding Systematized Nomenclature of Medicine, Clinical Terms (SNOMED CT) with complex and polysemy clinical terms may ask coder to have a high level knowledge domains, but simpler terms, coding require only knowledge. However, there are few studies quantitatively showing the relation between domain ability. So, we tried show relationship those two areas.We extracted diagnosis operation names from electronic medical records university hospital for 500 ophthalmology neurosurgery patients. The...