- Central Venous Catheters and Hemodialysis
- Bacterial biofilms and quorum sensing
- Antimicrobial Resistance in Staphylococcus
- Surgical Sutures and Adhesives
- Orthopedic Infections and Treatments
- Antimicrobial agents and applications
- Electrospun Nanofibers in Biomedical Applications
- Infective Endocarditis Diagnosis and Management
- Bacterial Identification and Susceptibility Testing
- Cerebrospinal fluid and hydrocephalus
- Antibiotics Pharmacokinetics and Efficacy
- Mosquito-borne diseases and control
- Polymer Surface Interaction Studies
- Nosocomial Infections in ICU
- Dental Implant Techniques and Outcomes
- Antibiotic Resistance in Bacteria
- Laser Applications in Dentistry and Medicine
- Viral gastroenteritis research and epidemiology
- Head and Neck Surgical Oncology
- Legionella and Acanthamoeba research
- Dental materials and restorations
- Vascular Procedures and Complications
- Viral Infections and Vectors
- Infection Control in Healthcare
- Infectious Aortic and Vascular Conditions
Zaans Medisch Centrum
2019
University Medical Center of the Johannes Gutenberg University Mainz
2001-2018
Johannes Gutenberg University Mainz
2001-2018
Institute of Medical Microbiology and Hygiene
1989-2018
University of Cologne
1988-2017
Heidelberg University
1998-2000
University of Münster
2000
Abstract In view of the increasing interest in possible role played by hospital and municipal wastewater systems selection antibiotic-resistant bacteria, biofilms were investigated using enterococci, staphylococci, Enterobacteriaceae, heterotrophic bacteria as indicator organisms. addition to wastewater, also drinking water from river bank filtrate estimate occurrence resistant their resistance genes, thus indicating transfer surface distribution network. Vancomycin-resistant enterococci...
The aim of the in vitro study was to examine bactericidal effect an Er:YAG laser on common dental implant surfaces.Seventy-two titanium platelets with 3 different surfaces--sandblasted and acid-etched (SA), plasma-sprayed (TPS), hydroxyapatite-coated (HA)--were incubated a suspension Streptococcus sanguinis (ATCC 10556). Irradiation at pulse energies 60 120 mJ frequency 10 pps performed computer-controlled XY translation stage. After treatment specimens were sonicated bacterial growth...
Infection continues to be one of the major complications cerebrospinal fluid (CSF) shunting procedures, and is caused mainly by skin-derived bacteria. Production an extracellular biofilm plays important role in pathogenesis shunt-associated infections protecting bacteria from immune mechanisms antibiotics. So far, removal original shunt implantation a new device has been only successful treatment for most patients. As alternative strategy prevent CSF infections, rifampin-impregnated silicone...
Abstract: Titanium platelets with a sand‐blasted and acid‐etched surface were coated bovine serum albumin incubated suspension of Porphyromonas gingivalis (ATCC 33277). Four groups total 48 specimens formed. Laser irradiation the ( n =12) was performed on computer‐controlled XY translation stage at pulse energy 60 mJ frequency 10 pps. Twelve treated an air powder system. After respective treatment, human gingival fibroblasts specimens. The proliferation rate determined by means fluorescence...
Central venous catheter infection presents an important problem in modern medicine, leading sometimes to a life-threatening situation for the patient as well contributing prolonged hospital stay and increase costs. We have evaluated vitro biocompatibility antimicrobial activity of silver-coated polyurethane designed use colonization-resistant, antiinfective catheter. Due comparatively low silver release, performed cell toxicity blood compatibility tests acute done with mice. The was tested...
Real-time quantification of Pseudomonas aeruginosa was performed in various wastewater systems including clinical, municipal wastewaters and inflow from a treatment plant. The highest concentrations P. aeruginosa-specific targets were detected clinical wastewaters. Limitations the detection system resulting inhibition or cross-reaction identified. Ciprofloxacin-resistant strains isolated after specific enrichment In some cases they also cultivated effluent plant, its downstream river water....
Abstract Background and Objectives To investigate the bactericidal effect of an 809 nm semiconductor laser alone, in combination with NaOCl/H 2 O irrigation root canals vitro. Study Design/Materials Methods A total 72 human single‐rooted teeth extracted for periodontal reasons were included. The crowns removed, roots shortened to a length 12 mm, enlarged up apical size #50 file. specimens autoclaved incubated suspension Streptococcus sanguinis (ATCC 10556). Laser irradiation was performed on...
A series of polyetherurethane films grafted by means gamma radiation with hydrophilic or reactive monomers (2-hydroxyethyl methacrylate, 2,3-epoxypropyl 2,3-dihydroxypropyl and acrylamide) partially chemically modified were subjected to various physico-chemical investigation methods involving water sorption, contact angle, protein adsorption measurements. From angle data the interfacial free energy sw between was calculated. It found that uptake increases grafting yield or, in case...
The increased incidence of nosocomial Legionnaires' disease in two hospitals prompted investigation possible environmental sources. In the search for an effective DNA-typing technique use hospital epidemiology, performance and convenience three methods-SfiI macrorestriction analysis (MRA), amplified fragment length polymorphism (AFLP), arbitrarily primed PCR (AP-PCR)-were compared. Twenty-nine outbreak-associated eight nonassociated strains Legionella pneumophila with 13 MRA types subtypes...
Infections of central venous lines are still a problem in daily medicine. Despite adequate antibiotic therapy, removal an infected catheter often becomes necessary. A simple procedure has been developed by which special hydrophilic (Secalon-Hydrocath) can be loaded with iodine. Iodine is complexed the polyvinylpyrrolidone surface coating Hydrocath and released during contact aqueous medium. The amount iodine depends on incubation time Lugol's solution. Antimicrobial activity catheters was...