A5006850835- Ear Surgery and Otitis Media
- Vestibular and auditory disorders
- Ear and Head Tumors
- Cardiac Arrest and Resuscitation
- Travel-related health issues
- Neuroscience of respiration and sleep
- Language, Metaphor, and Cognition
- Cardiovascular and Diving-Related Complications
- Speech and Audio Processing
- Spaceflight effects on biology
- High Altitude and Hypoxia
- Obstructive Sleep Apnea Research
- Voice and Speech Disorders
- Ichthyology and Marine Biology
- Language, Discourse, Communication Strategies
- Trauma and Emergency Care Studies
- Marine animal studies overview
- Respiratory Support and Mechanisms
- Botulinum Toxin and Related Neurological Disorders
- HIV Research and Treatment
- Hearing Loss and Rehabilitation
- Disaster Response and Management
- Neurobiology of Language and Bilingualism
- Digital Communication and Language
- Speech and dialogue systems
University of Cologne
1992-2025
University Hospital Cologne
2016-2024
University School
2024
Indiana University School of Medicine
2024
Indiana University
2024
Universitätsklinik für Hals-, Nasen- und Ohrenheilkunde
2023
Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde
2016-2022
Centrum für Integrierte Onkologie
2018-2019
Universitäts-HNO-Klinik Heidelberg
2018
Bielefeld University
2014
The common single-nucleotide polymorphism (SNP) brain-derived neurotrophic factor (BDNF) valine-to-methionine substitution at codon 66 (Val66Met) has been associated with differences in memory functions and cortical plasticity following brain stimulation. Other studies could not confirm these results, though, potential interactions of BDNF carrier status other learning-relevant SNPs are largely unknown. present study aimed to evaluate the effects Val66Met genotype on paired associative...
Zusammenfassung Ziel dieser Untersuchung war es, die Repräsentation von Frauen in der deutschsprachigen wissenschaftlichen Publikationslandschaft HNO-Heilkunde zu untersuchen. Die Autor*innenschaft wurde anhand Artikeln überprüft, zwischen 2013 und 2023 den 2 größten HNO-Fachzeitschriften (Laryngo-Rhino-Otologie, HNO) veröffentlicht wurden, um Häufigkeit prozentualen Anteil des Geschlechts bei Erst- Letztautor*innenschaft ermitteln. Insgesamt wurden 2631 Artikel untersucht. Bei 699 (26,6%)...
We measured the free amino acids in plasma of 58 patients with HIV infection and six persons risk group. The HIV+ had significantly increased concentrations arginine, phenylalanine, glutamate comparison both age- sex-matched controls members Glutamate only an advanced stage disease (WR 5 6 Walter Reed staging classification), whereas arginine phenylalanine independently stage. There was no correlation between acid number T4 T8 lymphocytes, sedimentation rate, existence or absence Kaposi's...
Infections of central venous lines are still a problem in daily medicine. Despite adequate antibiotic therapy, removal an infected catheter often becomes necessary. A simple procedure has been developed by which special hydrophilic (Secalon-Hydrocath) can be loaded with iodine. Iodine is complexed the polyvinylpyrrolidone surface coating Hydrocath and released during contact aqueous medium. The amount iodine depends on incubation time Lugol's solution. Antimicrobial activity catheters was...
Frey's syndrome is characterised as sweating, redness and warmth of the parotideal area often treated with botulinum toxin A. The objective this retrospective study was to prove whether dosage time-to-treatment intervals change after repeated injections.The charts patients, who were for during last 16 years, assessed. Three brands A available therapy. Minor test used confirm sweating before each treatment determine dosage. Constant amount injected per cm2 affected area. Patients consulted...
Hypobaric hypoxia (HH) during airline travel induces several (patho-) physiological reactions in the human body. Whereas severe is investigated thoroughly, very little known about effects of moderate or short-term hypoxia, e.g. flights. The aim present study was to analyse changes serum protein expression and activation signalling cascades volunteers staying for 30 min a simulated altitude equivalent travel. After approval local ethics committee, 10 participants were exposed (simulation 2400...
The aim was to investigate the prevalence of middle ear barotrauma (MEB) and establish risk factors MEB after repeated saltwater dives.In this prospective observational cohort study 28 divers were examined over 6 consecutive days diving in Red Sea, Egypt. Participants underwent an otoscopic examination before first dive, between each dive last dive. In addition, they performed Valsalva maneuver (VM) questioned about dive-related complaints. Otoscopic findings classified according TEED...
The digitization of aircraft cockpits places high demands on the colour vision pilots. present study investigates changes upon acute exposure to hypobaric hypoxia. digital Waggoner Computerized Color Vision Test and D-15 were performed by 54 healthy volunteers in a decompression chamber. Respective altitude levels sea level, 10,000 or 15,000 ft for periods 15 60 min, respectively. As min significant decrease perception was found between subjects at as compared control group well ft. No...
AbstractElevated plasma levels of glutamate (GLU) have been reported to occur in patients with malignancies and other immunodeficiency syndromes (IDS). To evaluate, whether GLU is useful as prognostic indicator, the concentrations were determined colorectal carcinoma (CRC), breast cancer (BRC), HIV-infection (HIV). The results correlated disease-stages, compared data obtained from benign diseases same organ, well sex-matched healthy volunteers. (volunteers: 27.4+17.6 μmol/1) elevated all BRC...
ORIGINAL RESEARCH article Front. Aging Neurosci., 05 November 2010Sec. Neurocognitive and Behavior Volume 2 - 2010 | https://doi.org/10.3389/fnagi.2010.00146
We investigated in a prospective, observational trial the feasibility of using Eustachian tube function test (ETFT) to measure effect repetitive pressure exposure during open seawater dives on function.The study included 28 adult divers six consecutive days diving Red Sea. Participants underwent otoscopy and ETFT before first dive, between each dive after last dive. regular tympanometry (R-tymp), Valsalva (V-tymp) swallowing (S-tymp). The R-tymp was obtained as 'baseline' peak pressure....
Introduction: The Eustachian tube plays a crucial role in pressure equalization between the middle ear and ambient for fast large differences. In patients with chronic dysfunction, balloon dilatation is increasingly used as surgical therapy. Subjectively, many report an improvement of symptoms postoperatively. Hence, there need to objectively measure this effect. Methods: objectivity was evaluated using precise method measuring function. hypo/hyperbaric chamber, 23 ears 13 were exposed...
Treatment with botulinum toxin A (BoNT) is the therapy of choice for many patients facial synkinesis. Repeated injections relieve hypertonicity and hyperkinesis reinnervated mimic muscles. Aim study was to prove if injection regime dosage BoNT change during long-time therapy.Retrospective analysis patients´ data, who were treated synkinesis from 1998 2018.Tertiary referral nerve centre.Injection pattern based on clinical symptoms, observations specialist previous treatment pattern....
Measurement of the Eustachian tube (ET) function is a challenge. The demand for precise and meaningful diagnostic tool increases-especially because more operative therapies are being offered without objective evidence. measurement ET by continuous impedance recording in pressure chamber an established method, although reliability measurements still unclear.Twenty-five participants (50 ears) were exposed to phases compression decompression hypo- hyperbaric chamber. reflecting parameters-ET...
The human body reacts to hypobaric hypoxia, e.g., during a stay at high altitude, with several mechanisms of adaption. Even short-time exposition hypoxia leads complex adaptions. Proteomics facilitates the possibility detect changes in metabolism due proteins. present study aims identify time-dependent protein expression for 30 and 60 min simulated altitude 15,000 ft. N = 80 male subjects were randomized assigned into four different groups: 40 ground control (GC30) (GC60) ft (HH30) (HH60)....