- Atmospheric chemistry and aerosols
- Plant responses to elevated CO2
- Atmospheric and Environmental Gas Dynamics
- Air Quality and Health Impacts
- Air Quality Monitoring and Forecasting
- RNA Research and Splicing
- Atmospheric Ozone and Climate
- Atmospheric aerosols and clouds
- Plant Water Relations and Carbon Dynamics
- RNA modifications and cancer
- Odor and Emission Control Technologies
- RNA and protein synthesis mechanisms
- Cancer-related gene regulation
- Lichen and fungal ecology
- Indoor Air Quality and Microbial Exposure
- Advanced Chemical Sensor Technologies
- Plant and animal studies
- Nuclear Structure and Function
- Biocrusts and Microbial Ecology
- Aquatic Ecosystems and Phytoplankton Dynamics
- X-ray Spectroscopy and Fluorescence Analysis
- Vehicle emissions and performance
- Epigenetics and DNA Methylation
- Geography and Environmental Studies
- Marine and environmental studies
Max Planck Institute for Chemistry
2014-2024
Martin Luther University Halle-Wittenberg
2004-2022
University of Applied Sciences Mainz
2020
Forschungszentrum Jülich
2011-2016
Max Planck Institute for Biogeochemistry
2003-2014
Max Planck Society
1999-2011
Agroscope
2010-2011
Federal Office for Agriculture
2010
University Hospital in Halle
2000
Justus-Liebig-Universität Gießen
1997-2000
Abstract. The Model of Emissions Gases and Aerosols from Nature (MEGANv2.1) together with the Modern-Era Retrospective Analysis for Research Applications (MERRA) meteorological fields were used to create a global emission data set biogenic volatile organic compounds (BVOC) available on monthly basis time period 1980–2010. This set, developed under Monitoring Atmospheric Composition Climate project (MACC), is called MEGAN–MACC. model estimated mean annual total BVOC 760 Tg (C) yr−1 consisting...
Chemical crosslinking in combination with mass spectrometry has matured into an alternative approach to derive low-resolution structural information of proteins and protein complexes. Yet, one the major drawbacks this strategy remains lack software that is able handle large MS datasets are created after chemical enzymatic digestion reaction mixtures. Here, we describe a software, termed StavroX, which been specifically designed for analyzing highly complex datasets. The StavroX was evaluated...
Cleavage and polyadenylation specificity factor (CPSF) is the central component of 3′ processing machinery for polyadenylated mRNAs in metazoans: CPSF recognizes signal AAUAAA, providing sequence both pre-mRNA cleavage polyadenylation, catalyzes cleavage. Here we show that seven polypeptides have been proposed to constitute CPSF, only four (CPSF160, CPSF30, hFip1, WDR33) are necessary sufficient reconstitute a subcomplex active AAUAAA-dependent whereas CPSF100, CPSF73, symplekin dispensable....
The spatial and temporal variability of the global fluxes carbonyl sulfide (COS) is discussed together with possible implications for total column atmospheric COS loading. input into atmosphere calculated as sum all known direct sources plus conversion carbon disulfide (CS 2 ) dimethyl (DMS) to by oxidation processes. Recent models are used predict COS, CS , DMS release from oceans uptake soils, plants, oceans. This forward approach constructing integrated has a large associated range...
Oculopharyngeal muscular dystrophy (OPMD) is an adult-onset disease characterized by progressive eyelid drooping, swallowing difficulties and proximal limb weakness. The autosomal dominant form of the caused short (GCG)8–13 expansions in PABP2 gene. This gene encodes poly(A) binding protein 2 (PABP2), abundant nuclear that binds with high affinity to nascent tails, stimulating their extension controlling length. In this work we report detected filamentous inclusions, which are pathological...
Abstract. The capacity for volatile isoprenoid production under standardized environmental conditions at a certain time (ES, the emission factor) is key characteristic in constructing inventories. However, there large variation published ES estimates any given species partly driven by dynamic modifications due to acclimation and stress responses. Here we review additional sources of that are measurement analytical techniques calculation averaging procedures, demonstrate estimations...
Abstract. We estimated the isoprene and monoterpene source strengths of a pristine tropical forest north Manaus in central Amazon Basin using three different micrometeorological flux measurement approaches. During early dry season campaign Cooperative LBA Airborne Regional Experiment (LBA-CLAIRE-2001), tower-based surface layer gradient (SLG) technique was applied simultaneously with relaxed eddy accumulation (REA) system. measurements vertical profiles within above convective boundary (CBL)...
A substantial amount of carbon is emitted by terrestrial vegetation as biogenic volatile organic compounds (VOC), which contributes to the oxidative capacity atmosphere, particle production and cycle. With regard budget biosphere, a release these regarded loss photosynthetically fixed carbon. The significance this for regional global cycles controversial. We estimate VOC in relation CO 2 taken up, based on our own enclosure micrometeorological flux measurements emissions exchange within...
Abstract. The rate of constitutive isoprenoid emissions from plants is driven by plant emission capacity under specified environmental conditions (ES, the factor) and responsiveness to instantaneous variations in environment. In models emission, ES has been often considered as intrinsic species-specific constant invariable time space. Here we analyze values field focusing on abiotic stresses, past developmental processes. reviewed studies highlight strong stress-driven, adaptive (previous...
Poly(A) tails of mRNAs are synthesized in the cell nucleus with a defined length, approximately 250 nucleotides mammalian cells. The same type length control is seen an vitro polyadenylation system reconstituted from three proteins: poly(A) polymerase, cleavage and specificity factor (CPSF), nuclear poly(A)-binding protein (PABPN1). CPSF, binding signal AAUAAA, PABPN1, growing tail, cooperatively stimulate polymerase such that complete tail one processive event, which terminates at...
Abstract. In models of plant volatile isoprenoid emissions, the instantaneous compound emission rate typically scales with plant's potential under specified environmental conditions, also called as factor, ES. most widely employed models, algorithms developed by Guenther and colleagues (1991, 1993), variation steady-state is described product ES light temperature response functions. When these are in atmospheric chemistry modeling community, species-specific values parameter defining curves...
Abstract. Characterization of daytime sources nitrous acid (HONO) is crucial to understand atmospheric oxidation and radical cycling in the planetary boundary layer. HONO numerous other trace constituents were measured on Mediterranean island Cyprus during CYPHEX (CYprus PHotochemical EXperiment) campaign summer 2014. Average volume mixing ratios 35 pptv (±25 pptv) with a ∕ NOx ratio 0.33, which was considerably higher than reported for most rural urban regions. Diel profiles showed peak...
The 3' ends of almost all eukaryotic mRNAs are generated in an essential two-step processing reaction: endonucleolytic cleavage extended precursor followed by the addition a poly(A) tail. By reconstituting reaction from overproduced and purified proteins, we provide minimal list 14 polypeptides that two stimulatory for RNA processing. In depending on polyadenylation signal AAUAAA, reconstituted system cleaves pre-mRNA at single preferred site corresponding to one used vivo. Among factor I...
Soil samples from arable land were investigated for their exchange of carbonyl sulfide (COS) with the atmosphere under controlled conditions using dynamic cuvettes in a climate chamber. The soil type acted as significant sink trace gas COS. Atmospheric COS mixing ratios, temperature, and water content found to be physicochemical parameters controlling uptake. Emission was never observed representative natural environment. compensation point (i.e., an ambient concentration where consumption...
Abstract Whereas for extra‐tropical regions model estimates of the emission volatile organic compounds (VOC) predict strong responses to annual cycles foliar biomass, light intensity and temperature, tropical stand out as a dominant source year round, with only little variability mainly due cycle biomass drought‐deciduous trees. As part Large Scale Biosphere Atmosphere Experiment in Amazônia (LBA‐EUSTACH), remote secondary forest site was visited dry‐to‐wet season transition campaign, trace...
We estimate isoprene emissions over tropical South America during 1997–2001 using column measurements of formaldehyde (HCHO) from the Global Ozone Monitoring Experiment (GOME) satellite instrument, GEOS‐Chem chemistry transport model, and MEGAN (Model Emissions Gases Aerosols Nature) bottom‐up inventory. is qualitatively consistent with in situ ground‐based aircraft concentration profiles HCHO, GOME HCHO data (r = 0.41; bias +35%), but has less skill reproducing wet season observations....
Abstract. Carbonyl sulfide (COS) is an atmospheric trace gas that holds great promise for studies of terrestrial carbon and water exchange. In leaves, COS follows the same pathway as CO2 during photosynthesis. Both gases are taken up in enzyme reactions, making uptake closely coupled at leaf scale. The biological background a hydrolysis reaction catalyzed by carbonic anhydrase. Based on this, we derive test simple kinetic model uptake, relate to fluxes equation was found predict realistic...
Abstract. As a contribution to the Large-Scale Biosphere-Atmosphere Experiment in Amazonia – Cooperative LBA Airborne Regional (LBA-CLAIRE-2001) field campaign heart of Amazon Basin, we analyzed temporal and spatial dynamics urban plume Manaus City during wet-to-dry season transition period July 2001. During flights, performed vertical stacks crosswind transects outflow downwind City, measuring comprehensive set trace constituents including O3, NO, NO2, CO, VOC, CO2, H2O. Aerosol loads were...
Abstract. Soil and biological soil crusts can emit nitrous acid (HONO) nitric oxide (NO). The terrestrial ground surface in arid semiarid regions is anticipated to play an important role the local atmospheric HONO budget, deemed represent one of unaccounted-for sources frequently observed field studies. In this study NO emissions from a representative variety crust samples Mediterranean island Cyprus were investigated under controlled laboratory conditions. A wide range fluxes was observed,...