A5086362171- Bone health and osteoporosis research
- Orthopaedic implants and arthroplasty
- Spine and Intervertebral Disc Pathology
- Medical Imaging and Analysis
- Elasticity and Material Modeling
- Bone Tissue Engineering Materials
- Bone and Joint Diseases
- Bone fractures and treatments
- Spinal Fractures and Fixation Techniques
- Cellular and Composite Structures
- Muscle activation and electromyography studies
- Cellular Mechanics and Interactions
- Pelvic and Acetabular Injuries
- Black Holes and Theoretical Physics
- Prosthetics and Rehabilitation Robotics
- Automotive and Human Injury Biomechanics
- Additive Manufacturing and 3D Printing Technologies
- Diagnosis and Treatment of Venous Diseases
- Cosmology and Gravitation Theories
- Hip and Femur Fractures
- Dental Implant Techniques and Outcomes
- Diabetic Foot Ulcer Assessment and Management
- Optical measurement and interference techniques
- Osteoarthritis Treatment and Mechanisms
- Traumatic Brain Injury Research
Dalian University of Technology
2016-2024
Xidian University
2023-2024
Shijiazhuang University
2021
Technical University of Malaysia Malacca
2019
Hamburg University of Technology
2013-2018
Universität Hamburg
2013-2018
University of Sheffield
2014-2017
Insigneo
2014-2017
Dalian University
2017
Cardiff University
2010-2011
Bone scaffolds are widely used as one of the main bone substitute materials. However, many scaffold microstructure topologies exist and it is still unclear which topology to use when designing for a specific application. The aim present study was reveal mechanism microstructure-driven performance thus provide guideline on design. Finite element (FE) models five TPMS (Diamond, Gyroid, Schwarz P, Fischer-Koch S F-RD) three traditional (Cube, FD-Cube Octa) were generated. effective compressive...
In vivo micro-computed tomography (µCT) scanning of small rodents is a powerful method for longitudinal monitoring bone adaptation. However, the life-time growth in makes it challenge to quantify local Therefore, aim this study was develop protocol, which can take into account large growth, adaptations over space and time. The entire right tibiae eight 14-week-old C57BL/6J female mice were consecutively scanned four times an µCT scanner using nominal isotropic image voxel size 10.4µm....
The use of Parathyroid Hormone (PTH) as bone anabolic is limited due to cost-benefit assessments. Preclinical studies evaluating the effects PTH on have reported variable and often contradictory results. Here, we applied a new approach using combination in-vivo longitudinal µCT, image processing techniques finite element models monitor early local changes in whole tibia (divided 40 compartments) mechanical properties female C57BL/6J mice treated with 1-34, compared controls. Compared...
Skeletal muscles have a highly organized hierarchical structure, whose main function is to generate forces for movement and stability. To understand the complex heterogeneous behaviors of muscles, computational modeling has advanced as non-invasive approach evaluate relevant mechanical quantities. Aiming improve musculoskeletal predictions, this paper presents framework 3D deformable that includes continuum constitutive representation, parametric determination, model validation, fiber...
Details of the anatomy and behavior structures responsible for human eye movements have been extensively elaborated since first modern biomechanical models were introduced. Based on these findings, a finite element model ocular adduction is developed based connective measured optic nerve (ON) properties, as well active contractility bilaminar extraocular muscles (EOMs), but incorporating novel feature that globe translation not otherwise constrained so realistic kinematics can be simulated....
The aim of this work was to examine the association between polymorphisms in nuclear respiratory factor (NRF2) gene and endurance capacity measured prior after an 18-wk training program young Chinese men. phenotypes were running economy (RE) VO(2max). RE determined by measuring submaximal VO(2) for 5 min at a constant speed 12 km x h (-1) VO(2max) during incremental test volitional exhaustion. Genomic DNA extracted from white cells peripheral blood genotypes examined SNPrs12594956, rs8031031...
Abstract Background Recent advances in diagnostic imaging and associated software have enabled the transformation of anatomical structures into finite element (FE) models facilitating computerized facial modelling. The work presented employs personalized data for use planning predicting outcome maxillofacial surgery. current process relies on either freehand and/or commercial two‐dimensional (2D) three‐dimensional (3D) surgical packages, but validity these packages has been questioned. In...
Micro-Computed Tomography (microCT) images are used to measure morphometric and densitometric properties of bone, develop finite element (FE) models estimate mechanical properties. However, there concerns about the invasiveness microCT imaging due X-rays ionising radiation induced by repeated scans on same animal. Therefore, best compromise between dose image quality should be chosen for each preclinical application. In this study, we investigated effect integration time (time bone is...
ABSTRACT Trabecular bone score (TBS) rests on the textural analysis of dual-energy X-ray absorptiometry (DXA) to reflect decay in trabecular structure characterizing osteoporosis. Yet, its discriminative power fracture studies remains incomprehensible because prior biomechanical tests found no correlation with vertebral strength. To verify this result possibly owing an unrealistic setup and cover a wide range loading scenarios, data from three previous using different experimental settings...
Abstract Branched actin network supports cell migration through extracellular microenvironments. However, it is unknown how intracellular proteins adapt the elastic properties of to highly varying resistance. Here we develop a three-dimensional assembling model simulate realistic self-assembling process by encompassing and their dynamic interactions. Combining this multiscale with finite element method, reveal that can not only sense variation resistance but also self-adapt its remodeling...
Objective: To select the most appropriate internal fixation method based on Pauwels angle, in order to provide a new concept for clinical accurate treatment of femoral neck fractures (FNFs). Methods: FNFs models 30° ; 40° 50° 60° were created respectively. For ≤ , 1, 2 and 3 Cannulated Compression Screws (CCS) Porous Tantalum (PTS) used fix fracture models. 3CCS Medial Buttress Plate (MBP) combined with fracture. Based results finite element (FE) analysis, biomechanical properties each model...
Purpose: In order to clarify the role of optic nerve (ON) as a load on ocular rotation, we developed finite element model (FEM) incremental adduction induced by active contractility extraocular muscles (EOMs), with and without tethering ON. Methods: Three-dimensional (3-D) horizontal rectus EOM geometries were obtained from magnetic resonance imaging five healthy adults, measured constitutive tissue properties used. Active passive strain energies EOMs defined using ABAQUS (Dassault Systemes)...
A bstract In this paper, we consider a coupling mechanism between the kinetic term and gravity, in which function F ( R ) is introduced into of five-dimensional scalar field. Based on scenario, investigate localization fields three specific braneworld models: Minkowski brane, de Sitter Anti-de brane. The brane models considered here are regular with no singularity for curvature. For Minkowshi case, zero mode can always be localized massive modes or quasi-localized dS 4 two forms factor...
A large number of pelvic injuries are seriously unstable, with mortality rates reaching 19%. Approximately 60% related to the posterior ring. However, selection a fixation method for ring injury remains challenging problem orthopedic surgeons. The aim present study is investigate biomechanical performance five different approaches and thus provide guidance on choice treatment approach in clinical setting. finite element (FE) model, including L3-L5 lumbar vertebrae, sacrum, full pelvis, was...