A5071980276- Cardiac and Coronary Surgery Techniques
- Cardiac Valve Diseases and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Mechanical Circulatory Support Devices
- Transplantation: Methods and Outcomes
- Cardiac Structural Anomalies and Repair
- Cardiac Ischemia and Reperfusion
- Coronary Interventions and Diagnostics
- Nitric Oxide and Endothelin Effects
- Aortic Disease and Treatment Approaches
- Pulmonary Hypertension Research and Treatments
- Cardiac Arrest and Resuscitation
- Infective Endocarditis Diagnosis and Management
- Electrospun Nanofibers in Biomedical Applications
- Pleural and Pulmonary Diseases
- Frailty in Older Adults
- Organ Transplantation Techniques and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac tumors and thrombi
- Blood transfusion and management
- Telomeres, Telomerase, and Senescence
- Tissue Engineering and Regenerative Medicine
- Aortic aneurysm repair treatments
- Renal Transplantation Outcomes and Treatments
- Cardiovascular Function and Risk Factors
Montreal Heart Institute
2016-2025
Université de Montréal
2016-2025
Carrier (United States)
2017-2022
Centre Hospitalier de l’Université de Montréal
2017
St. Charles Medical Center
2016
University of the West Indies
2003
Institute of Medical Biology
2002
Hôpital Lariboisière
1996-2000
Biostatistical Consulting (United States)
2000
Memorial Sloan Kettering Cancer Center
2000
Background: Older adults undergoing aortic valve replacement (AVR) are at risk for malnutrition. The association between preprocedural nutritional status and midterm mortality has yet to be determined. Methods: FRAILTY-AVR (Frailty in Aortic Valve Replacement) prospective multicenter cohort study was conducted 2012 2017 14 centers 3 countries. Patients ≥70 years of age who underwent transcatheter or surgical AVR were eligible. Mini Nutritional Assessment-Short Form assessed by trained...
Inhaled administration of milrinone reduces pulmonary artery pressure. Pulmonary hypertension (PH) and right heart failure are associated with difficult separation from cardiopulmonary bypass (CPB). Therefore, inhaled could facilitate CPB.To determine the impact timing milrinone.A retrospective analysis our experience on high-risk patients receiving was conducted to evaluate postoperative course after drug.Seventy-three received June 2002 February 2005. Mean age 64+/-13 years, a mean...
Off-pump coronary artery bypass surgery (OPCAB) has been revived and gained popularity, although the exact subsets of patients who might benefit most from this technique are unknown. The aim retrospective study was to compare results grafting (CABG) in octogenarians using cardiopulmonary (CPB) or OPCAB techniques.Over a 5-year period (1995-1999), 125 older than 80 years age were operated for isolated myocardial revascularization (63 CPB 62 with OPCAB). There no statistically significant...
Age-associated telomere shortening leads to replicative senescence of human endothelial cells (EC). Risk factors for cardiovascular disease (CVD) accelerate ageing, while there is a concomitant rise in oxidative stress known promote stress-induced (SIS) vitro. Of all risk CVD, smoking most associated with the development inflammation and accelerated atherosclerosis due prooxidant–antioxidant imbalance. We tested hypothesis that SIS predominates EC isolated from chronic smokers premature...
The use of antiplatelet drugs to treat acute myocardial infarction, unstable angina, coronary syndrome and secondary prevention following percutaneous interventions is well accepted. However, it constitutes a serious risk bleeding for patients undergoing artery bypass grafting surgery (CABG). We evaluated the effect aspirin clopidogrel (CPDG), both irreversible platelet aggregation inhibitors, on operative determined optimal timing their discontinuation before surgery.Between July 2001...
The purpose of this study is to report our experience with del Nido cardioplegia (DNC) in the setting minimally invasive aortic valve surgery. Forty-six consecutive patients underwent replacement (AVR) through a "J" ministernotomy: twenty-five received DNC (Group 1) and 21 standard blood (SBC) 2). rate ventricular fibrillation at unclamping was significantly lower group (12% vs 52%, p=0.004), as well postoperative creatinine kinase-MB (CK-MB) values (11.4±5.2 17.7±6.9 µg/L, p=0.004). There...