A5049496356- RNA Interference and Gene Delivery
- Material Dynamics and Properties
- Advanced biosensing and bioanalysis techniques
- Field-Flow Fractionation Techniques
- Pickering emulsions and particle stabilization
- DNA and Nucleic Acid Chemistry
- Lipid Membrane Structure and Behavior
- nanoparticles nucleation surface interactions
- Electrostatics and Colloid Interactions
- Environmental Chemistry and Analysis
- Surface Modification and Superhydrophobicity
- Spectroscopy and Quantum Chemical Studies
- Hydrogels: synthesis, properties, applications
- Advanced Polymer Synthesis and Characterization
- Supramolecular Self-Assembly in Materials
- Gold and Silver Nanoparticles Synthesis and Applications
- Proteins in Food Systems
- Surfactants and Colloidal Systems
Sapienza University of Rome
2020-2022
Politecnico di Milano
2016-2019
Mylan (South Africa)
2017-2019
Tecnologia Energia Ambiente Materiali (Italy)
2019
MSSCORPS (Taiwan)
2017
Curculio Institute
2017
By experimenting on model colloids where depletion forces can be carefully tuned and quantified, we show that attractive interactions consistently "promote" particle settling, so much the sedimentation velocity of a moderately concentrated dispersion even exceed its single-particle value. At larger volume fraction ϕ, however, hydrodynamic hindrance eventually takes over. Hence, v(ϕ) actually displays nonmonotonic trend may threaten stability settling front to thermal perturbations. Finally,...
Equilibrium gels formed by the reversible association of limited-valence colloids display a remarkable spatially uniform dynamics.
Overcoming the systemic administration of chemotherapy to reduce drug toxicity and application personalised medicine are two major challenges in treatment cancer. To this aim, efforts focused on finding novel nanomaterials for targeted drugs bioactive molecules tumor sites. DNA-based hydrogels promising candidates these applications. However, while such materials fairly known from a structural physical standpoint, their effects cell cultures far less investigated. Here, we studied biological...
We experimentally investigate the equilibrium gel formation in a binary mixture of DNA nanostars. The binding rules, encoded sequence nanostar ends, are such that each component is able to form only intra-species bonds. Reducing excluded volume by properly designing nanostars, we show two interpenetrating unconnected gels sample on cooling, forms at temperature controlled selected sequence. dynamic light scattering correlation functions non-common three-step relaxation process due splitting...
We propose a new method to produce fluorinated nanoparticles (NPs) based on ab initio reversible addition-fragmentation chain transfer (RAFT) emulsion polymerization without the use of toxic surfactants. NP size, surface charge, and chemistry can be controlled via adoption different macromolecular agents produced RAFT amphiphilic monomers. Thanks this versatility, interparticle interactions easily tuned by changing solvent composition temperature. In addition, refractive index density...
Due to its exquisite sensitivity interfacial properties, thermophoresis, i.e., particle motion driven by thermal gradients, can provide novel, exclusive, and often surprising information on the structural properties of colloidal or macromolecular fluids particle/solvent interactions at nanoscale. Here, using an all-optical excitation technique, lensing, we show that thermophoresis be profitably exploited investigate self-association amphiphilic block copolymer, poloxamer P407, which takes...
We have investigated the stationary sedimentation profiles of colloidal gels obtained by an arrested phase-separation process driven depletion forces, which been compressed either natural gravity or a centrifugal acceleration ranging between 6g and 2300g. Our measurements show that gel rheological properties display drastic change when particle volume fraction exceeds value [Formula: see text], barely depends on strength interparticle attractive forces consolidate network. In particular,...
Intracluster bonds in hyperbranched DNA polymers prevent percolation transition.