A5017574831- Medical Research and Treatments
- Cancer Research and Treatments
- Protein Interaction Studies and Fluorescence Analysis
- Pharmacological Effects of Natural Compounds
- Cancer Mechanisms and Therapy
- Catalytic Processes in Materials Science
- S100 Proteins and Annexins
- Neurological Disease Mechanisms and Treatments
- Microbial Metabolism and Applications
- Cytokine Signaling Pathways and Interactions
- Aluminum Alloy Microstructure Properties
- Catalysis and Hydrodesulfurization Studies
- Cancer-related molecular mechanisms research
- interferon and immune responses
- Healthcare and Venom Research
- RNA modifications and cancer
- Photonic and Optical Devices
- Lanthanide and Transition Metal Complexes
- Hydrogen Storage and Materials
- Drug Transport and Resistance Mechanisms
- Magnesium Alloys: Properties and Applications
- Catalysis and Oxidation Reactions
- Medicinal Plants and Bioactive Compounds
- Advancements in Battery Materials
- Solidification and crystal growth phenomena
Xiamen University
2016-2025
Environment and Plant Protection Research Institute
2024-2025
Shandong University of Technology
2025
Hainan Medical University
2025
Shandong First Medical University
2024
State Key Laboratory of Information Engineering in Surveying Mapping and Remote Sensing
2024
Union Hospital
2024
Huazhong University of Science and Technology
2024
Chengdu University
2021-2023
Children’s Hospital of Fudan University Xiamen Branch
2022
Phlorizin (PHL) is a natural compound with strong antioxidant properties mainly found in apples. In this paper, the interaction mechanism of PHL pepsin and trypsin was comparatively evaluated by computer simulation, fluorescence spectra, circular dichroism (CD), fourier transform infrared (FT-IR) spectra at molecular level. Fluorescence showed that quenches pepsin/trypsin static quenching. Thermodynamic parameters indicated binds to through hydrogen bonds van der Waals forces, electrostatic...
9-Hydroxyphenanthrene (9-OHPhe), the representative hydroxyl metabolite of phenanthrene, has generated increasing concern as it is potentially hazardous to organisms. Herein, multispectroscopic and molecular docking techniques were applied investigate interaction human serum albumin (HSA) with 9-hydroxyphenanthrene (9-OHPhe) under simulated physiological conditions. Steady-state fluorescence time-resolved spectral analysis showed that 9-OHPhe quenched HSA through a mixed static dynamic...
Silicosis is an interstitial lung disease (ILD) caused by prolonged inhalation of silica particles. Acute injury (ALI) a critical clinical syndrome involving bilateral infiltration and acute hypoxic respiratory failure. However, there currently no effective treatment for these two diseases. Previous research has established that cyclic adenosine monophosphate (cAMP) pivotal in the pathogenesis silicosis injury. Phosphodiesterase 4 (PDE4) hydrolase enzyme cAMP, BI 1015550, as inhibitor PDE4B,...
Areca nut (AN) was classified as a carcinogen by the International Agency for Research on Cancer (IARC) of WHO in 2003. AN has same carcinogenic components cigarettes, such benzo[a]pyrene (B[a]P) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), but its effects interactions with genetic factors related to lung cancer have rarely been investigated. METHODS: Here, propensity score-matched case‒control study conducted Hainan, which included 445 patients cancer-free controls. Then,...
To achieve higher energy density, LiCoO2 (LCO) is being developed for high-voltage operation at raised charge cutoff voltages up to 4.6 V vs Li/Li+, which however beyond the electrochemical stability window of carbonate-based electrolytes. In this work, a novel electrolyte additive 2,4,6-tris(4-fluorophenyl)boroxin (TFPB) proposed enhancing interfacial LCO. Thanks TFPB additive, LCO cathode exhibits substantially improved capacity retention 84.6% after 200 cycles 1C high V, surpassing 63.2%...
Ni-rich LiNixCoyMnzO2 (NCM, xNi ≥ 0.9) layered materials are appealing cathode candidates for future-generation higher-energy-density lithium-ion batteries (LIBs). However, structural and interfacial instability of cathodes needs to be addressed prior the large-scale deployment in electric vehicles. Herein, a diboron electrolyte additive 5,5,5′,5′-tetramethyl-2,2′-bi-1,3,2-dioxaborinane (TBDB) is proposed constructing stable LiNi0.9Co0.05Mn0.05O2 (NCM90)/electrolyte interface, thus improving...
Oncology nurses are at high risk of developing compassion fatigue (CF) because the persistent exposure to patients' suffering and death. Empathy is a prerequisite cognitive reaction for CF. Nurses with greater empathy levels more prone develop an emotional connection patients. However, it this kind close bonds that led experience deep sense grief. Cumulative grief may eventually into This study examined grief, CF, evaluated correlation among empathy, verified role as mediator relationship...
Gene expression profiling of tissue cells with spatial context is in high demand to reveal cell types, locations, and intercellular or molecular interactions for physiological pathological studies. With rapid advances barcoding chemistry sequencing chemistry, spatially resolved transcriptome (SRT) techniques have emerged quantify gene samples by correlating transcripts their locations using diverse strategies. These provide both physical structure characteristics are poised revolutionize...
Interaction of inorganic mercury(<sc>ii</sc>) with catalase was investigated using spectroscopic methods. Moreover, molecular docking used to distinguish the interactions between different species and catalase.
Combining multi-spectroscopy, docking with MD simulations, the interactions of 1-hydroxypyrene BSA and adverse effects on were investigated.
Background: Guizhou province is located in southwest China with abundant genetic, linguistic and cultural diversity. The Bouyei one of the 18 officially recognised minority groups Guizhou, accounting for about 97% total population China. However, genetic history forensic characterisation people largely unknown due to a lack data.Aim: We aim investigate polymorphisms population, as well relationships between other East Asian populations.Subjects methods: genotyped 19 X-STRs 188 males 165...
We present a simple colorimetric assay for EV71 virus detection based on the aggregation of 4-mercaptobenzoic acid (4-MBA) and melamine (MA) modified silver nanoparticles (4-MBA-MA-AgNPs) in presence Mn2+. The EV71-Ab1 was incubated 96-well plate EV71-Ab2 labeled surface three-dimensional nanoflower-like MnO2-PEG (3D-MnO2-PEG). After layer-by-layer immunoreactions, corresponding 3D-MnO2-PEG-Ab2 were captured plate. With addition Vitamin C (Vc), Mn2+ released from 3D-MnO2-PEG then...